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Issues

Volume 3, Issue 10
1 October 2004
Issue Cover
All Issues
ISSN 1535-7163
EISSN 1538-8514
Issue Sections

ARTICLE

Novel single-stranded oligonucleotides that inhibit signal transducer and activator of transcription 3 induce apoptosis in vitro and in vivo in prostate cancer cell lines
Beverly E. Barton; Thomas F. Murphy; Ping Shu; Hosea F. Huang; Marcus Meyenhofen; Arnold Barton
View articletitled, Novel single-stranded oligonucleotides that inhibit signal transducer and activator of transcription 3 induce apoptosis <em>in vitro</em> and <em>in vivo</em> in prostate cancer cell lines
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Targeting heterogeneous nuclear ribonucleoparticule A1 and A2 proteins by RNA interference promotes cell death in transformed but not in normal mouse cell lines
Caroline Patry; Bruno Lemieux; Raymund J. Wellinger; Benoit Chabot
View articletitled, Targeting heterogeneous nuclear ribonucleoparticule A1 and A2 proteins by RNA interference promotes cell death in transformed but not in normal mouse cell lines
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A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells
Christopher M. Incles; Christoph M. Schultes; Helena Kempski; Heike Koehler; Lloyd R. Kelland; Stephen Neidle
View articletitled, A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells
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Topoisomerase-IIα expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel
Virginie Durbecq; Marianne Paesmans; Fatima Cardoso; Christine Desmedt; Angelo Di Leo; Stephen Chan; Kay Friedrichs; Tamas Pinter; Simon Van Belle; Elizabeth Murray; István Bodrogi; Euan Walpole; Bernard Lesperance; Stefan Korec; John Crown; Peter Simmonds; Thimothy J. Perren; Jean-Yves Leroy; Ghizlane Rouas; Christos Sotiriou; Martine Piccart; Denis Larsimont
View articletitled, Topoisomerase-IIα expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel
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Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O6-alkylguanine-DNA alkyltransferase
Vincent A. Barvaux; Paul Lorigan; Malcolm Ranson; Amanda M. Gillum; R. Stanley McElhinney; T. Brian H. McMurry; Geoffrey P. Margison
View articletitled, Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by <em>O</em><sup>6</sup>-alkylguanine-DNA alkyltransferase
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Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide
Xiuxian Jiang; Baoguang Zhao; Robert Britton; Lynette Y. Lim; Dan Leong; Jasbinder S. Sanghera; Bin-Bing S. Zhou; Edward Piers; Raymond J. Andersen; Michel Roberge
View articletitled, Inhibition of Chk1 by the G<sub>2</sub> DNA damage checkpoint inhibitor isogranulatimide
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G2 cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium
Robin M. Scaife
View articletitled, G<sub>2</sub> cell cycle arrest, down-regulation of cyclin B, and induction of mitotic catastrophe by the flavoprotein inhibitor diphenyleneiodonium
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The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice
Nhu-An Pham; James W. Jacobberger; Aaron D. Schimmer; Pinjiang Cao; Marcella Gronda; David W. Hedley
View articletitled, The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice
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Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias
Marina Konopleva; Elena Elstner; Teresa J. McQueen; Twee Tsao; Andrey Sudarikov; Wei Hu; Wendy D. Schober; Rui-Yu Wang; David Chism; Steven M. Kornblau; Anas Younes; Steven J. Collins; H. Phillip Koeffler; Michael Andreeff
View articletitled, Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias
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Bortezomib rapidly suppresses ubiquitin thiolesterification to ubiquitin-conjugating enzymes and inhibits ubiquitination of histones and type I inositol 1,4,5-trisphosphate receptor
Qun Xu; Michelle Farah; Jack M. Webster; Richard J.H. Wojcikiewicz
View articletitled, Bortezomib rapidly suppresses ubiquitin thiolesterification to ubiquitin-conjugating enzymes and inhibits ubiquitination of histones and type I inositol 1,4,5-trisphosphate receptor
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Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model
Gilda G. Hillman; Yu Wang; Omer Kucuk; Mingxin Che; Daniel R. Doerge; Mark Yudelev; Michael C. Joiner; Brian Marples; Jeffrey D. Forman; Fazlul H. Sarkar
View articletitled, Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model
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BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors
Hidesuke Fukazawa; Kohji Noguchi; Atsuko Masumi; Yuko Murakami; Yoshimasa Uehara
View articletitled, BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors
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Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists
Jesus V. Soriano; Ningfei Liu; Yang Gao; Zhu-Jun Yao; Toshio Ishibashi; Charles Underhill; Terrence R. Burke, Jr.; Donald P. Bottaro
View articletitled, Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists
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Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway
Eddy Pasquier; Manon Carré; Bertrand Pourroy; Laurence Camoin; Ouafa Rebaï; Claudette Briand; Diane Braguer
View articletitled, Antiangiogenic activity of paclitaxel is associated with its cytostatic effect, mediated by the initiation but not completion of a mitochondrial apoptotic signaling pathway
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Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome
Qing Chen; Sheng Tong; Mark W. Dewhirst; Fan Yuan
View articletitled, Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome
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Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in α-tubulin
Frank Loganzo; Malathi Hari; Tami Annable; Xingzhi Tan; Daniel B. Morilla; Sylvia Musto; Arie Zask; Joshua Kaplan; Albert A. Minnick, Jr.; Michael K. May; Semiramis Ayral-Kaloustian; Marianne S. Poruchynsky; Tito Fojo; Lee M. Greenberger
View articletitled, Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in α-tubulin
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Novel peptide ligands for integrin α4β1 overexpressed in cancer cells
Masahito Mikawa; Henry Wang; Linlang Guo; Ruiwu Liu; Jan Marik; Yoshikazu Takada; Kit Lam; Derick Lau
View articletitled, Novel peptide ligands for integrin α<sub>4</sub>β<sub>1</sub> overexpressed in cancer cells
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Minireview

Targeting ErbB receptor signaling: A pan-ErbB approach to cancer
Carolyn D. Britten
View articletitled, Targeting ErbB receptor signaling: A pan-ErbB approach to cancer
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  • Online ISSN 1538-8514
  • Print ISSN 1535-7163

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