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Issues

Volume 22, Issue 8
1 August 2023
Issue Cover
All Issues
ISSN 1535-7163
EISSN 1538-8514

Highlights

Selected Articles from This Issue
View articletitled, Selected Articles from This Issue
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First Disclosures

ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies
Adam S. Chervin; Jennifer D. Stone; Iwona Konieczna; Kelly M. Calabrese; Ningyan Wang; Dipica Haribhai; Feng Dong; Michael K. White; Luis E. Rodriguez; Gail T. Bukofzer; Paul A. Ellis; Cormac Cosgrove; Claudie Hecquet; Jerry D. Clarin; Joann P. Palma; Edward B. Reilly
View articletitled, ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies
Supplementary data
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Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers
Wei Zhou; Peng Fang; Dongan Yu; Hongyuan Ren; Meng You; Long Yin; Fei Mei; Huikai Zhu; Zhenzhen Wang; Hui Xu; Yuxia Cao; Xiaowei Sun; Xiaohong Xu; Jianjun Bi; Jin Wang; Lanping Ma; Xin Wang; Lin Chen; Yongliang Zhang; Xiaowei Cen; Xi Zhu; Liguang Lou; Datao Liu; Xiaoding Tan; Jinliang Yang; Tao Meng; Jingkang Shen
View articletitled, Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers
Supplementary data
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Review

The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma
Bin Wang; Dong Ding; Xiaoan Zhang; Junxi Zhang; Huanhuan Zhang; Xinxin Liu; Hui Chang; Zhan Gao; Zengli Yu
View articletitled, The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma
Supplementary data
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Small Molecule Therapeutics

Bromo- and Extra-Terminal Domain Inhibitors Induce Mitochondrial Stress in Pancreatic Ductal Adenocarcinoma
Manjul Rana; Rita G. Kansal; Bijay Bisunke; Jie Fang; David Shibata; Amandeep Bajwa; Jun Yang; Evan S. Glazer
View articletitled, Bromo- and Extra-Terminal Domain Inhibitors Induce Mitochondrial Stress in Pancreatic Ductal Adenocarcinoma
Supplementary data
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APR-246 Enhances Colorectal Cancer Sensitivity to Radiotherapy
Xuqin Xie; Chuanwen Fan; Bin Luo; Jing Zhang; Lasse D. Jensen; Jonas Burman; Carolin Jönsson; Anna Ljusberg; Peter Larsson; Zengren Zhao; Xiao-Feng Sun
View articletitled, APR-246 Enhances Colorectal Cancer Sensitivity to Radiotherapy
Supplementary data
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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
Susmita Ghosh; Fan Fan; Reid T. Powell; Jason Roszik; Yong Sung Park; Clifford Stephan; Manu Sebastian; Lin Tan; Alexey V. Sorokin; Philip L. Lorenzi; Scott Kopetz; Lee M. Ellis; Rajat Bhattacharya
View articletitled, Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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Companion Diagnostic, Pharmacogenomic, and Cancer Biomarkers

Discordance of HER2 Expression and/or Amplification on Repeat Testing
Timothy P. DiPeri; Kathleen Kong; Kaushik Varadarajan; Daniel D. Karp; Jaffer A. Ajani; Shubham Pant; Michael F. Press; Sarina A. Piha-Paul; Ecaterina E. Dumbrava; Funda Meric-Bernstam
View articletitled, Discordance of HER2 Expression and/or Amplification on Repeat Testing
Supplementary data
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Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication
Junko Murai; Michele Ceribelli; Haiqing Fu; Christophe E. Redon; Ukhyun Jo; Yasuhisa Murai; Mirit I. Aladjem; Craig J. Thomas; Yves Pommier
View articletitled, Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale within the United States of Bavencio® (avelumab), a pharmaceutical owned by Merck. If any resulting funds are received, they would not be used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-8514
  • Print ISSN 1535-7163

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  • Copyright © 2023 by the American Association for Cancer Research.
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