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1 September 2022
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Scheme of the different signaling pathways where YES1 phosphorylation participates in cancer cells to promote proliferation, migration, invasion, and metastasis. Read the full article by Garmendia and colleagues on page 1371.Close Modal - PDF Icon PDF LinkTable of Contents
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ISSN 1535-7163
EISSN 1538-8514
Highlights
Review
Small Molecule Therapeutics
Large Molecule Therapeutics
Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody–Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer
Stephen J. Gregson; Kathryn Pugh; Neki Patel; Shameen Afif-Rider; Balakumar Vijayakrishnan; Kathleen Santos; Jitka Riedl; Ian Hutchinson; Gyoung-Dong Kang; K. Phin Chooi; Rhiannon Beard; Lauren Adams; Conor S. Barry; Kathryn Ball; Luke A. Masterson; Mary McFarlane; John A. Hartley; Philip W. Howard
Anti-Extra Domain B Splice Variant of Fibronectin Antibody–Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade
Andrea T. Hooper; Kimberly Marquette; Chao-Pei Betty Chang; Jonathon Golas; Sadhana Jain; My-Hanh Lam; Magali Guffroy; Mauricio Leal; Hadi Falahatpisheh; Divya Mathur; Ting Chen; Kerry Kelleher; Kiran Khandke; Elwira Muszynska; Frank Loganzo; Edward Rosfjord; Judy Lucas; Zhengyan Kan; Chakrapani Subramanyam; Christopher O'Donnell; Dario Neri; Hans-Peter Gerber; Chad May; Puja Sapra
Targeting Drug Resistance
Inhibition of Integrin αVβ3 Signaling Improves the Antineoplastic Effect of Bexarotene in Cutaneous T-Cell Lymphoma
Florencia Cayrol; Maria V. Revuelta; Mercedes Debernardi; Alejandra Paulazo; Jude M. Phillip; Nahuel Zamponi; Helena Sterle; María C. Díaz Flaqué; Cynthia Magro; Rossella Marullo; Erin Mulvey; Jia Ruan; Graciela A. Cremaschi; Leandro Cerchietti
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