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The Glutathione-activated Thiopurine Prodrugs trans-6-(2-Acetylvinylthio)guanine and cis-6-(2-Acetylvinylthio)purine Cause Less in Vivo Toxicity than 6-Thioguanine after Single- and Multiple-Dose Regimens1

Mol Cancer Ther (2002) 1 (13): 1211–1220.
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