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Wafik S. El-Deiry
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Journal Articles

Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells

Open Access
Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry
Journal: Molecular Cancer Research
Mol Cancer Res (2022) 20 (4): 622–636.
https://doi.org/10.1158/1541-7786.MCR-21-0149
Published: 01 April 2022
View articletitled, Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells
Open the PDF for Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Differential Effects of Clinically Relevant N- versus C-Terminal Truncating CDKN1A Mutations on Cisplatin Sensitivity in Bladder Cancer

Free
Rahmat K. Sikder, Moataz Ellithi, Robert N. Uzzo, David J. Weader, Alexander L. Metz, Ali Behbahani, Erica R. McKenzie, Wafik S. El-Deiry, Philip H. Abbosh
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (3): 403–413.
https://doi.org/10.1158/1541-7786.MCR-19-1200
Published: 01 March 2021
View articletitled, Differential Effects of Clinically Relevant N- versus C-Terminal Truncating CDKN1A Mutations on Cisplatin Sensitivity in Bladder Cancer
Open the PDF for Differential Effects of Clinically Relevant N- versus C-Terminal Truncating CDKN1A Mutations on Cisplatin Sensitivity in Bladder Cancer in another window
Includes: Supplementary data
Journal Articles

ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer

Free
Avital Lev, Amriti R. Lulla, Brian C. Ross, Marie D. Ralff, Petr B. Makhov, David T. Dicker, Wafik S. El-Deiry
Journal: Molecular Cancer Research
Mol Cancer Res (2018) 16 (5): 754–766.
https://doi.org/10.1158/1541-7786.MCR-17-0614
Published: 30 April 2018
View articletitled, ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer
Open the PDF for ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer in another window
Includes: Supplementary data