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Peter M. Glazer
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Journal Articles

Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of DNA Repair

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Jonathan Dow, Adam Krysztofiak, Yanfeng Liu, Daniel A. Colon-Rios, Faye A. Rogers, Peter M. Glazer
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (12): 2057–2067.
https://doi.org/10.1158/1541-7786.MCR-21-0456
Published: 02 December 2021
View articletitled, Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of DNA Repair
Open the PDF for Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of DNA Repair in another window
Includes: Supplementary data
Journal Articles

Ku80-Targeted pH-Sensitive Peptide–PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation

Available to Purchase
Alanna R. Kaplan, Ha Pham, Yanfeng Liu, Stanley Oyaghire, Raman Bahal, Donald M. Engelman, Peter M. Glazer
Journal: Molecular Cancer Research
Mol Cancer Res (2020) 18 (6): 873–882.
https://doi.org/10.1158/1541-7786.MCR-19-0661
Published: 02 June 2020
View articletitled, Ku80-Targeted pH-Sensitive Peptide–PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation
Open the PDF for Ku80-Targeted pH-Sensitive Peptide–PNA Conjugates Are Tumor Selective and Sensitize Cancer Cells to Ionizing Radiation in another window
Includes: Supplementary data
Journal Articles

Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1

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Yuhong Lu, Yanfeng Liu, Sebastian Oeck, Peter M. Glazer
Journal: Molecular Cancer Research
Series: Author Choice
Mol Cancer Res (2018) 16 (10): 1458–1469.
https://doi.org/10.1158/1541-7786.MCR-17-0637
Published: 02 October 2018
View articletitled, Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1
Open the PDF for Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1 in another window
Journal Articles

PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF

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Parker L. Sulkowski, Susan E. Scanlon, Sebastian Oeck, Peter M. Glazer
Journal: Molecular Cancer Research
Series: Author Choice
Mol Cancer Res (2018) 16 (8): 1241–1254.
https://doi.org/10.1158/1541-7786.MCR-17-0581
Published: 31 July 2018
View articletitled, PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF
Open the PDF for PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF in another window
Includes: Supplementary data
Journal Articles

Abstract B25: “TargetDBR”—A DNA repair drug and target discovery collaboration: Exploiting synthetic lethal, high content, and functional cellular reporter assays to accelerate DNA repair targeted drug discovery

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Jonathan J. Hollick, Laura Abriola, Francoise Bono, Denise Hegan, Pamela Klingbeil, Yanfeng Liu, Ranjini Sundaram, Yulia V. Surovtseva, Mark Whittaker, Ranjit S. Bindra, Peter M. Glazer
Journal: Molecular Cancer Research
Mol Cancer Res (2017) 15 (4_Supplement): B25.
https://doi.org/10.1158/1557-3125.DNAREPAIR16-B25
Published: 02 April 2017
View articletitled, Abstract B25: “TargetDBR”—A DNA repair drug and target discovery collaboration: Exploiting synthetic lethal, high content, and functional cellular reporter assays to accelerate DNA repair targeted drug discovery
Journal Articles

DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy

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Antonia A. Nemec, Laura Abriola, Jane S. Merkel, Elisa de Stanchina, Michelle DeVeaux, Daniel Zelterman, Peter M. Glazer, Joann B. Sweasy
Journal: Molecular Cancer Research
Mol Cancer Res (2017) 15 (3): 269–280.
https://doi.org/10.1158/1541-7786.MCR-16-0227-T
Published: 28 February 2017
View articletitled, DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy
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Includes: Supplementary data
Journal Articles

miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair

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Jennifer R. Czochor, Parker Sulkowski, Peter M. Glazer
Journal: Molecular Cancer Research
Mol Cancer Res (2016) 14 (4): 363–373.
https://doi.org/10.1158/1541-7786.MCR-15-0399
Published: 14 April 2016
View articletitled, miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair
Open the PDF for miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair in another window
Includes: Supplementary data
Journal Articles

YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors

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Gregory C. Stachelek, Elizabeth Peterson-Roth, Yanfeng Liu, Rafael J. Fernandez, III, Luke R.G. Pike, Jack M. Qian, Laura Abriola, Denton Hoyer, William Hungerford, Janie Merkel, Peter M. Glazer
Journal: Molecular Cancer Research
Mol Cancer Res (2015) 13 (10): 1389–1397.
https://doi.org/10.1158/1541-7786.MCR-15-0036
Published: 18 October 2015
View articletitled, YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors
Open the PDF for YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors in another window
Journal Articles

Hypoxic Stress Facilitates Acute Activation and Chronic Downregulation of Fanconi Anemia Proteins

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Susan E. Scanlon, Peter M. Glazer
Journal: Molecular Cancer Research
Mol Cancer Res (2014) 12 (7): 1016–1028.
https://doi.org/10.1158/1541-7786.MCR-13-0628
Published: 01 July 2014
View articletitled, Hypoxic Stress Facilitates Acute Activation and Chronic Downregulation of Fanconi Anemia Proteins
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Includes: Supplementary data