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Marc Ladanyi
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Journal Articles

Impact of Rare and Multiple Concurrent Gene Fusions on Diagnostic DNA Methylation Classifier in Brain Tumors

Kristyn Galbraith, Jonathan Serrano, Guomiao Shen, Ivy Tran, Cheyanne C. Slocum, Courtney Ketchum, Zied Abdullaev, Rust Turakulov, Tejus Bale, Marc Ladanyi, Purvil Sukhadia, Michael Zaidinski, Kerry Mullaney, Sara DiNapoli, Benjamin L. Liechty, Marissa Barbaro, Jeffrey C. Allen, Sharon L. Gardner, Jeffrey Wisoff, David Harter, Eveline Teresa Hidalgo, John G. Golfinos, Daniel A. Orringer, Kenneth Aldape, Jamal Benhamida, Kazimierz O. Wrzeszczynski, George Jour, Matija Snuderl
Journal: Molecular Cancer Research
Mol Cancer Res (2024) 22 (1): 21–28.
https://doi.org/10.1158/1541-7786.MCR-23-0627
Published: 02 January 2024
View article titled, Impact of Rare and Multiple Concurrent Gene Fusions on Diagnostic DNA Methylation Classifier in Brain Tumors
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Includes: Supplementary data
Journal Articles

MYC Promotes Tyrosine Kinase Inhibitor Resistance in ROS1-Fusion-Positive Lung Cancer

Sudarshan R. Iyer, Igor Odintsov, Adam J. Schoenfeld, Evan Siau, Marissa S. Mattar, Elisa de Stanchina, Inna Khodos, Alexander Drilon, Gregory J. Riely, Marc Ladanyi, Romel Somwar, Monika A. Davare
Journal: Molecular Cancer Research
Mol Cancer Res (2022) 20 (5): 722–734.
https://doi.org/10.1158/1541-7786.MCR-22-0025
Published: 04 May 2022
View article titled, <em>MYC</em> Promotes Tyrosine Kinase Inhibitor Resistance in <em>ROS1</em>-Fusion-Positive Lung Cancer
Open the PDF for <em>MYC</em> Promotes Tyrosine Kinase Inhibitor Resistance in <em>ROS1</em>-Fusion-Positive Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor

Emily K. Slotkin, Anita S. Bowman, Max F. Levine, Filemon Dela Cruz, Diego F. Coutinho, Glorymar I. Sanchez, Nestor Rosales, Shakeel Modak, William D. Tap, Mrinal M. Gounder, Katherine A. Thornton, Nancy Bouvier, Daoqi You, Gunes Gundem, Justin T. Gerstle, Todd E. Heaton, Michael P. LaQuaglia, Leonard H. Wexler, Paul A. Meyers, Andrew L. Kung, Elli Papaemmanuil, Ahmet Zehir, Marc Ladanyi, Neerav Shukla
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (7): 1146–1155.
https://doi.org/10.1158/1541-7786.MCR-20-0722
Published: 01 July 2021
View article titled, Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
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Includes: Supplementary data
Journal Articles

Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival

Ryan N. Ptashkin, Carlos Pagan, Rona Yaeger, Sumit Middha, Jinru Shia, Kevin P. O'Rourke, Michael F. Berger, Lu Wang, Robert Cimera, Jiajing Wang, David S. Klimstra, Leonard Saltz, Marc Ladanyi, Ahmet Zehir, Jaclyn F. Hechtman
Journal: Molecular Cancer Research
Mol Cancer Res (2017) 15 (6): 708–713.
https://doi.org/10.1158/1541-7786.MCR-16-0352
Published: 01 June 2017
View article titled, Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival
Open the PDF for Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival in another window
Includes: Supplementary data
Journal Articles

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

Jaclyn F. Hechtman, Ahmet Zehir, Rona Yaeger, Lu Wang, Sumit Middha, Tao Zheng, David M. Hyman, David Solit, Maria E. Arcila, Laetitia Borsu, Jinru Shia, Efsevia Vakiani, Leonard Saltz, Marc Ladanyi
Journal: Molecular Cancer Research
Mol Cancer Res (2016) 14 (3): 296–301.
https://doi.org/10.1158/1541-7786.MCR-15-0392-T
Published: 14 March 2016
View article titled, Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF
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Includes: Supplementary data
Journal Articles

AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants

Jaclyn F. Hechtman, Justyna Sadowska, Jason T. Huse, Laetitia Borsu, Rona Yaeger, Jinru Shia, Efsevia Vakiani, Marc Ladanyi, Maria E. Arcila
Journal: Molecular Cancer Research
Mol Cancer Res (2015) 13 (6): 1003–1008.
https://doi.org/10.1158/1541-7786.MCR-15-0062-T
Published: 01 June 2015
View article titled, AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants
Open the PDF for AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants in another window
Journal Articles

Cell Cycle Regulator Gene CDC5L, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma

Xin-Yan Lu, Yaojuan Lu, Yi-Jue Zhao, Kim Jaeweon, Jason Kang, Li Xiao-Nan, Gouqing Ge, Rene Meyer, Laszlo Perlaky, John Hicks, Murali Chintagumpala, Wei-Wen Cai, Marc Ladanyi, Richard Gorlick, Ching C. Lau, Debananda Pati, Michael Sheldon, Pulivarthi H. Rao
Journal: Molecular Cancer Research
Mol Cancer Res (2008) 6 (6): 937–946.
https://doi.org/10.1158/1541-7786.MCR-07-2115
Published: 01 June 2008
View article titled, Cell Cycle Regulator Gene <em>CDC5L</em>, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma
Open the PDF for Cell Cycle Regulator Gene <em>CDC5L</em>, a Potential Target for 6p12-p21 Amplicon in Osteosarcoma in another window
Includes: Supplementary data