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Leonidas C. Platanias
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Journal Articles

PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation

Free
Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Sergio Barajas, Wenjie Cai, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Chonghua Yao, Yuxia Yang, Katherine Strube, Odelia Satchivi, Jianmin Sun, Lars Rönnstrand, James M. Croop, H. Scott Boswell, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Madina Sukhanova, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu
Journal: Molecular Cancer Research
Mol Cancer Res (2024) 22 (1): 94–103.
https://doi.org/10.1158/1541-7786.MCR-23-0115
Published: 02 January 2024
View articletitled, PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation
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Journal Articles

Targeting ULK1 Decreases IFNγ-Mediated Resistance to Immune Checkpoint Inhibitors

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Sarah E. Fenton, Markella Zannikou, Liliana Ilut, Mariafausta Fischietti, Chunni Ji, Chidera V. Oku, Curt M. Horvath, I. Caroline Le Poole, Marcus Bosenberg, Elizabeth T. Bartom, Masha Kocherginsky, Leonidas C. Platanias, Diana Saleiro
Journal: Molecular Cancer Research
Mol Cancer Res (2023) 21 (4): 332–344.
https://doi.org/10.1158/1541-7786.MCR-22-0684
Published: 01 April 2023
View articletitled, Targeting ULK1 Decreases IFNγ-Mediated Resistance to Immune Checkpoint Inhibitors
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Includes: Supplementary data
Journal Articles

Potent Antineoplastic Effects of Combined PI3Kα–MNK Inhibition in Medulloblastoma

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Frank Eckerdt, Jonathan B. Bell, Elspeth M. Beauchamp, Jessica Clymer, Gavin T. Blyth, Ewa M. Kosciuczuk, Quanhong Ma, David Z. Chen, Craig Horbinski, Stewart Goldman, Hidayatullah G. Munshi, Rintaro Hashizume, Leonidas C. Platanias
Journal: Molecular Cancer Research
Mol Cancer Res (2019) 17 (6): 1305–1315.
https://doi.org/10.1158/1541-7786.MCR-18-1193
Published: 03 June 2019
View articletitled, Potent Antineoplastic Effects of Combined PI3Kα–MNK Inhibition in Medulloblastoma
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Includes: Supplementary data
Journal Articles

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

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Jonathan B. Bell, Frank Eckerdt, Harshil D. Dhruv, Darren Finlay, Sen Peng, Seungchan Kim, Barbara Kroczynska, Elspeth M. Beauchamp, Kristen Alley, Jessica Clymer, Stewart Goldman, Shi-Yuan Cheng, C. David James, Ichiro Nakano, Craig Horbinski, Andrew P. Mazar, Kristiina Vuori, Priya Kumthekar, Jeffrey Raizer, Michael E. Berens, Leonidas C. Platanias
Journal: Molecular Cancer Research
Mol Cancer Res (2018) 16 (1): 32–46.
https://doi.org/10.1158/1541-7786.MCR-17-0397
Published: 01 January 2018
View articletitled, Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
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Includes: Supplementary data
Journal Articles

MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma

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Jonathan B. Bell, Frank D. Eckerdt, Kristen Alley, Lisa P. Magnusson, Hridi Hussain, Yingtao Bi, Ahmet Dirim Arslan, Jessica Clymer, Angel A. Alvarez, Stewart Goldman, Shi-Yuan Cheng, Ichiro Nakano, Craig Horbinski, Ramana V. Davuluri, C. David James, Leonidas C. Platanias
Journal: Molecular Cancer Research
Mol Cancer Res (2016) 14 (10): 984–993.
https://doi.org/10.1158/1541-7786.MCR-16-0172
Published: 13 October 2016
View articletitled, MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma
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Includes: Supplementary data
Journal Articles

Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer

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Krishan Kumar, Christina R. Chow, Kazumi Ebine, Ahmet D. Arslan, Benjamin Kwok, David J. Bentrem, Frank D. Eckerdt, Leonidas C. Platanias, Hidayatullah G. Munshi
Journal: Molecular Cancer Research
Mol Cancer Res (2016) 14 (2): 216–227.
https://doi.org/10.1158/1541-7786.MCR-15-0285
Published: 14 February 2016
View articletitled, Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Interferon Receptor Signaling in Malignancy: A Network of Cellular Pathways Defining Biological Outcomes

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Eleanor N. Fish, Leonidas C. Platanias
Journal: Molecular Cancer Research
Mol Cancer Res (2014) 12 (12): 1691–1703.
https://doi.org/10.1158/1541-7786.MCR-14-0450
Published: 17 December 2014
View articletitled, Interferon Receptor Signaling in Malignancy: A Network of Cellular Pathways Defining Biological Outcomes
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