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James C. Costello
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Journal Articles

Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast

Joseph L. Sottnik, Evelyn K. Bordeaux, Sanjana Mehrotra, Sarah E. Ferrara, Andrew E. Goodspeed, James C. Costello, Matthew J. Sikora
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (8): 1270–1282.
https://doi.org/10.1158/1541-7786.MCR-21-0025
Published: 01 August 2021
View article titled, Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast
Open the PDF for Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast in another window
Includes: Supplementary data
Journal Articles

MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1

Lauren K. Jillson, Leah C. Rider, Lindsey U. Rodrigues, Lina Romero, Anis Karimpour-Fard, Cera Nieto, Claire Gillette, Kathleen Torkko, Etienne Danis, Elizabeth E. Smith, Rosalie Nolley, Donna M. Peehl, M. Scott Lucia, James C. Costello, Scott D. Cramer
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (7): 1123–1136.
https://doi.org/10.1158/1541-7786.MCR-20-0913
Published: 01 July 2021
View article titled, <em>MAP3K7</em> Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of <em>CHD1</em>
Open the PDF for <em>MAP3K7</em> Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of <em>CHD1</em> in another window
Includes: Supplementary data
Journal Articles

Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers

Josh Lewis Stern, Grace Hibshman, Kevin Hu, Sarah E. Ferrara, James C. Costello, William Kim, Pablo Tamayo, Thomas R. Cech, Franklin W. Huang
Journal: Molecular Cancer Research
Mol Cancer Res (2020) 18 (7): 1050–1062.
https://doi.org/10.1158/1541-7786.MCR-19-1244
Published: 02 July 2020
View article titled, Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers
Open the PDF for Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers in another window
Includes: Supplementary data
Journal Articles

Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination

Satoshi Washino, Leah C. Rider, Lina Romero, Lauren K. Jillson, Trisiani Affandi, Angela M. Ohm, Elaine T. Lam, Mary E. Reyland, James C. Costello, Scott D. Cramer
Journal: Molecular Cancer Research
Mol Cancer Res (2019) 17 (10): 1985–1998.
https://doi.org/10.1158/1541-7786.MCR-18-1335
Published: 01 October 2019
View article titled, Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination
Open the PDF for Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination in another window
Includes: Supplementary data
Journal Articles

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

Andrew Goodspeed, Laura M. Heiser, Joe W. Gray, James C. Costello
Journal: Molecular Cancer Research
Series: Author Choice
Mol Cancer Res (2016) 14 (1): 3–13.
https://doi.org/10.1158/1541-7786.MCR-15-0189
Published: 15 January 2016
View article titled, Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics
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Journal Articles

RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer

Erin M. Griner, Garrett M. Dancik, James C. Costello, Charles Owens, Sunny Guin, Michael G. Edwards, David L. Brautigan, Dan Theodorescu
Journal: Molecular Cancer Research
Mol Cancer Res (2015) 13 (3): 483–492.
https://doi.org/10.1158/1541-7786.MCR-14-0420
Published: 18 March 2015
View article titled, RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer
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Includes: Supplementary data