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J. William Harbour
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Journal Articles

Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma

Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Vivian Chua, Anna Han, Edward J. Hartsough, Jeffim N. Kuznetsoff, J. William Harbour, Andrew E. Aplin
Journal: Molecular Cancer Research
Mol Cancer Res (2022) 20 (8): 1260–1271.
https://doi.org/10.1158/1541-7786.MCR-21-0657
Published: 05 August 2022
View article titled, Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma
Open the PDF for Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma in another window
Includes: Supplementary data
Journal Articles

Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase

Hongzhuang Peng, Joel Cassel, Daniel S. McCracken, Jeremy W. Prokop, Eleonora Sementino, Mitchell Cheung, Paul R. Collop, Alexander Polo, Surbhi Joshi, Jacob P. Mandell, Kasirajan Ayyanathan, David Hinds, S. Bruce Malkowicz, J. William Harbour, Anne M. Bowcock, Joseph Salvino, Eileen J. Kennedy, Joseph R. Testa, Frank J. Rauscher, III
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (7): 1099–1112.
https://doi.org/10.1158/1541-7786.MCR-20-0080
Published: 01 July 2021
View article titled, Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase
Open the PDF for Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase in another window
Includes: Supplementary data
Journal Articles

Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma

Jeffim N. Kuznetsoff, Dawn A. Owens, Andy Lopez, Daniel A. Rodriguez, Nancy T. Chee, Stefan Kurtenbach, Daniel Bilbao, Evan R. Roberts, Claude-Henry Volmar, Claes Wahlestedt, Shaun P. Brothers, J. William Harbour
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (2): 215–222.
https://doi.org/10.1158/1541-7786.MCR-20-0434
Published: 03 February 2021
View article titled, Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma
Open the PDF for Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma in another window
Includes: Supplementary data