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David J. Kwiatkowski
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Journal Articles

The Codon 72 TP53 Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis

Jun-Hung Cho, Bhaumik Patel, Santosh Bonala, Hossein Mansouri, Sasikanth Manne, Surya Kumari Vadrevu, Shanawaz Ghouse, Che-Pei Kung, Maureen E. Murphy, Aristotelis Astrinidis, Elizabeth P. Henske, David J. Kwiatkowski, Maciej M. Markiewski, Magdalena Karbowniczek
Journal: Molecular Cancer Research
Mol Cancer Res (2019) 17 (8): 1639–1651.
https://doi.org/10.1158/1541-7786.MCR-18-1292
Published: 01 August 2019
View article titled, The Codon 72 <em>TP53</em> Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis
Open the PDF for The Codon 72 <em>TP53</em> Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis in another window
Includes: Supplementary data
Journal Articles

MCL1 and DEDD Promote Urothelial Carcinoma Progression

Andrew L. Hong, Jennifer L. Guerriero, Mihir B. Doshi, Bryan D. Kynnap, Won Jun Kim, Anna C. Schinzel, Rebecca Modiste, Amy J. Schlauch, Rosalyn M. Adam, David J. Kwiatkowski, Rameen Beroukhim, Anthony Letai, Jonathan E. Rosenberg, William C. Hahn
Journal: Molecular Cancer Research
Mol Cancer Res (2019) 17 (6): 1294–1304.
https://doi.org/10.1158/1541-7786.MCR-18-0963
Published: 03 June 2019
View article titled, MCL1 and DEDD Promote Urothelial Carcinoma Progression
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Includes: Supplementary data
Journal Articles

Tuberin Regulates Prostaglandin Receptor–Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells

Chenggang Li, Xiaolei Liu, Yang Liu, Erik Zhang, Kantha Medepalli, Kouhei Masuda, Na Li, Kathryn A. Wikenheiser-Brokamp, Andrew Osterburg, Michael T. Borchers, Elizabeth J. Kopras, David R. Plas, Julia Sun, David N. Franz, Jamie K. Capal, Maxwell Mays, Yang Sun, David J. Kwiatkowski, Anya Alayev, Marina K. Holz, Darcy A. Krueger, Brian J. Siroky, Jane J. Yu
Journal: Molecular Cancer Research
Mol Cancer Res (2017) 15 (10): 1318–1330.
https://doi.org/10.1158/1541-7786.MCR-17-0077
Published: 01 October 2017
View article titled, Tuberin Regulates Prostaglandin Receptor–Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells
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Journal Articles

A Vascular Model of Tsc1 Deficiency Accelerates Renal Tumor Formation with Accompanying Hemangiosarcomas

Jarrett D. Leech, Stephen H.T. Lammers, Sam Goldman, Neil Auricchio, Roderick T. Bronson, David J. Kwiatkowski, Mustafa Sahin
Journal: Molecular Cancer Research
Mol Cancer Res (2015) 13 (3): 548–555.
https://doi.org/10.1158/1541-7786.MCR-14-0178
Published: 01 March 2015
View article titled, A Vascular Model of Tsc1 Deficiency Accelerates Renal Tumor Formation with Accompanying Hemangiosarcomas
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Includes: Supplementary data
Journal Articles

Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC2-Deficient Cells to the Antimetabolite 6-Aminonicotinamide

Andrey A. Parkhitko, Carmen Priolo, Jonathan L. Coloff, Jihye Yun, Julia J. Wu, Kenji Mizumura, Wenping Xu, Izabela A. Malinowska, Jane Yu, David J. Kwiatkowski, Jason W. Locasale, John M. Asara, Augustine M.K. Choi, Toren Finkel, Elizabeth P. Henske
Journal: Molecular Cancer Research
Mol Cancer Res (2014) 12 (1): 48–57.
https://doi.org/10.1158/1541-7786.MCR-13-0258-T
Published: 01 January 2014
View article titled, Autophagy-Dependent Metabolic Reprogramming Sensitizes TSC2-Deficient Cells to the Antimetabolite 6-Aminonicotinamide
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Includes: Supplementary data
Journal Articles

Equivalent Benefit of Rapamycin and a Potent mTOR ATP-Competitive Inhibitor, MLN0128 (INK128), in a Mouse Model of Tuberous Sclerosis

Yanan Guo, David J. Kwiatkowski
Journal: Molecular Cancer Research
Mol Cancer Res (2013) 11 (5): 467–473.
https://doi.org/10.1158/1541-7786.MCR-12-0605
Published: 14 May 2013
View article titled, Equivalent Benefit of Rapamycin and a Potent mTOR ATP-Competitive Inhibitor, MLN0128 (INK128), in a Mouse Model of Tuberous Sclerosis
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Journal Articles

Molecular Dissection of AKT Activation in Lung Cancer Cell Lines

Yanan Guo, Jinyan Du, David J. Kwiatkowski
Journal: Molecular Cancer Research
Mol Cancer Res (2013) 11 (3): 282–293.
https://doi.org/10.1158/1541-7786.MCR-12-0558
Published: 19 March 2013
View article titled, Molecular Dissection of AKT Activation in Lung Cancer Cell Lines
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Includes: Supplementary data