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Journal Articles

Abstract PR10: IK-595, a MEK-RAF complex inhibitor, obviates CRAF mediated resistance resulting in superior RAS/MAPK pathway inhibition and anti-tumor activity in RAS/RAF altered cancers

Eric Haines, Michael Burke, Rachel Catterall, Victor De Jesus, Bin Li, Joseph D. Manna, George Punkosdy, Oksana Zavidij, Sarah R. Wessel, Grace Werosta, Jill Cavanaugh, Sheila Newhouse, Aravind Basavapathruni, Lan Xu, Sergio Santillana, X. Michelle Zhang, Sabine K. Ruppel
Journal: Molecular Cancer Research
Mol Cancer Res (2023) 21 (5_Supplement): PR10.
https://doi.org/10.1158/1557-3125.RAS23-PR10
Published: 01 May 2023
View article titled, Abstract PR10: IK-595, a MEK-RAF complex inhibitor, obviates CRAF mediated resistance resulting in superior RAS/MAPK pathway inhibition and anti-tumor activity in RAS/RAF altered cancers
Journal Articles

A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth

Fan Yang, Jezabel Rodriguez-Blanco, Jun Long, Marzena Swiderska-Syn, Daniel T. Wynn, Bin Li, Chen Shen, Anmada Nayak, Yuguang Ban, Xiaodian Sun, Robert K. Suter, Heather J. McCrea, Anthony J. Capobianco, Nagi G. Ayad, David J. Robbins
Journal: Molecular Cancer Research
Mol Cancer Res (2022) 20 (11): 1598–1610.
https://doi.org/10.1158/1541-7786.MCR-22-0182
Published: 03 November 2022
View article titled, A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth
Open the PDF for A Druggable UHRF1/DNMT1/GLI Complex Regulates Sonic Hedgehog–Dependent Tumor Growth in another window
Includes: Supplementary data
Journal Articles

TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast–Mediated Epithelial–Mesenchymal Transition in Colorectal Cancer

Mengdi Yang, Dan Li, Zhiyuan Jiang, Changcan Li, Suyuan Ji, Jing Sun, Yujie Chang, Shunyi Ruan, Zhiyu Wang, Rui Liang, Xueyu Dai, Bin Li, Hui Zhao
Journal: Molecular Cancer Research
Mol Cancer Res (2022) 20 (8): 1247–1259.
https://doi.org/10.1158/1541-7786.MCR-21-0924
Published: 05 August 2022
View article titled, TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast–Mediated Epithelial–Mesenchymal Transition in Colorectal Cancer
Open the PDF for TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast–Mediated Epithelial–Mesenchymal Transition in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Protein Kinase D–Dependent Downregulation of Immediate Early Genes through Class IIA Histone Deacetylases in Acute Lymphoblastic Leukemia

Guangyan Sun, Anna Shvab, Guy J. Leclerc, Bin Li, Felipe Beckedorff, Ramin Shiekhattar, Julio C. Barredo
Journal: Molecular Cancer Research
Mol Cancer Res (2021) 19 (8): 1296–1307.
https://doi.org/10.1158/1541-7786.MCR-20-0808
Published: 01 August 2021
View article titled, Protein Kinase D–Dependent Downregulation of Immediate Early Genes through Class IIA Histone Deacetylases in Acute Lymphoblastic Leukemia
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Includes: Supplementary data
Journal Articles

Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex

Xiaoqing Han, Prathibha Ranganathan, Christos Tzimas, Kelly L. Weaver, Ke Jin, Luisana Astudillo, Wen Zhou, Xiaoxia Zhu, Bin Li, David J. Robbins, Anthony J. Capobianco
Journal: Molecular Cancer Research
Series: Author Choice
Mol Cancer Res (2017) 15 (9): 1173–1183.
https://doi.org/10.1158/1541-7786.MCR-17-0241
Published: 31 August 2017
View article titled, Notch Represses Transcription by PRC2 Recruitment to the Ternary Complex
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Includes: Supplementary data
Journal Articles

TNFα Accelerates Monocyte to Endothelial Transdifferentiation in Tumors by the Induction of Integrin α5 Expression and Adhesion to Fibronectin

Bin Li, Ambra Pozzi, Pampee P. Young
Journal: Molecular Cancer Research
Mol Cancer Res (2011) 9 (6): 702–711.
https://doi.org/10.1158/1541-7786.MCR-10-0484
Published: 01 June 2011
View article titled, TNFα Accelerates Monocyte to Endothelial Transdifferentiation in Tumors by the Induction of Integrin α<sub>5</sub> Expression and Adhesion to Fibronectin
Open the PDF for TNFα Accelerates Monocyte to Endothelial Transdifferentiation in Tumors by the Induction of Integrin α<sub>5</sub> Expression and Adhesion to Fibronectin in another window