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The AACR editors are proud to present this selection of impactful articles published in Molecular Cancer Research.
- Control of proliferation and cancer growth by the Hippo signaling pathway.
Ehmer U, Sage J. Molecular Cancer Research 2015; DOI:10.1158/1541-7786.MCR-15-0305 [Published OnlineFirst October 2, 2015].
Rapid Impact Article
- A mechanism for asymmetric cell division resulting in proliferative asynchronicity.
Dey-Guha I, Alves CP, Yeh AC, Salony, Sole X, Darp R, et al. Molecular Cancer Research 2015;13:223–30.
- Cyclin A2 and CDK2 as novel targets of aspirin and salicylic acid: a potential role in cancer prevention.
Dachineni R, Ai G, Kumar DR, Sadhu SS, Tummala H, Bhat GJ. Molecular Cancer Research 2015; DOI:10.1158/1541-7786.MCR-15-0360. [Published OnlineFirst December 18, 2015].
- Active FOXO1 is a key determinant of isoform-specific progesterone receptor transactivation and senescence programming.
Diep CH, Knutson TP, Lange CA. Molecular Cancer Research 2015; DOI:10.1158/1541-7786.MCR-15-0431. [Published OnlineFirst November 17, 2015].
- Linking cancer metabolism to DNA repair and accelerated senescence.
Efimova EV, Takahashi S, Shamsi NA, Wu D, Labay E, Ulanovskaya OA, et al. Molecular Cancer Research 2015; DOI:10.1158/1541-7786.MCR-15-0263. [Published OnlineFirst November 4, 2015].
- miR-200c targets CDK2 and suppresses tumorigenesis in renal cell carcinoma.
Wang X, Chen X, Han W, Ruan A, Chen L, Wang R, et al. Molecular Cancer Research 2015;13:1567–77.
- Therapeutic targeting of nuclear γ-tubulin in RB1-negative tumors.
Lindström L, Villoutreix BO, Lehn S, Hellsten R, Nilsson E, Crneta E, et al. Molecular Cancer Research 2015;13:1073–82.
- The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell–attracting cytokines.
Perrigue PM, Silva ME, Warden CD, Feng NL, Reid MA, Mota DJ, et al. Molecular Cancer Research 2015;13:636–50.
- A p53/ARF-dependent anticancer barrier activates senescence and blocks tumorigenesis without impacting apoptosis.
Sinha VC, Qin L, Li Y. Molecular Cancer Research 2015;13:231–8.
- CDK2 transcriptional repression is an essential effector in p53-dependent cellular senescence—implications for therapeutic intervention.
Zalzali H, Nasr B, Harajly M, Basma H, Ghamloush F, Ghayad S, et al. Molecular Cancer Research 2015;13:29–40.
- p53 promotes cell survival due to the reversibility of its cell-cycle checkpoints.
Lukin DJ, Carvajal LA, Liu W, Resnick-Silverman L, Manfredi JJ. Molecular Cancer Research 2015;13:16–28.
- SIRT1 inactivation evokes antitumor activities in NSCLC through the tumor suppressor p27.
Zhu L, Chiao CY, Enzer KG, Stankiewicz AJ, Faller DV, Dai Y. Molecular Cancer Research 2015;13:41–9.