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Research Article May 23 2022
A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance
Mol Cancer Res molcanres.0941.2021.
Review Article May 23 2022
Emerging roles of the copper-CTR1 axis in tumorigenesis
Mol Cancer Res molcanres.0056.2022-1-17 21:06:19.613.
Research Article May 13 2022
TGF-β-induced FLRT3 attenuation is essential for cancer-associated fibroblast-mediated epithelial-mesenchymal transition in colorectal cancer
Mengdi Yang; Dan Li; Zhiyuan Jiang; Changcan Li; Suyuan Ji; Jing Sun; Yujie Chang; Shunyi Ruan; Zhiyu Wang; Rui Liang; Xueyu Dai; Bin Li; Hui Zhao
Mol Cancer Res molcanres.MCR-21-0924-E.2021.
Research Article May 13 2022
Ceramide kinase inhibition drives ferroptosis and sensitivity to cisplatin in mutant KRAS lung cancer by dysregulating VDAC-mediated mitochondria function
Mol Cancer Res molcanres.0085.2022.
Research Article May 11 2022
Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing
Minh-Tam Pham; Anuj Gupta; Harshath Gupta; Ajay Vaghasia; Alyza Skaist; McKinzie A. Garrison; Jonathan B. Coulter; Michael C. Haffner; S. Lilly Zheng; Jianfeng Xu; Christina DeStefano Shields; William B. Isaacs; Sarah J. Wheelan; William G. Nelson; Srinivasan Yegnasubramanian
Mol Cancer Res (2022)
Research Article May 11 2022
Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma
David A. Schoenfeld; Royce Zhou; Sakellarios Zairis; William Su; Nicole Steinbach; Deepti Mathur; Ankita Bansal; Alexis L. Zachem; Bertilia Tavarez; Dan Hasson; Emily Bernstein; Raul Rabadan; Ramon Parsons
Mol Cancer Res (2022)
Research Article May 9 2022
Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia
Jung-Lin Wu; Hsin-Yi Wu; Shang-Ju Wu; Ho-Yang Tsai; Shao-Hsing Weng; Kuen-Tyng Lin; Liang-In Lin; Chi-Yuan Yao; Margarita Zamanova; Yi-Yuan Lee; Takashi Angata; Hwei-Fang Tien; Yu-Ju Chen; Kuo-I Lin
Mol Cancer Res molcanres.MCR-21-0722-E.2021.
Research Article May 9 2022
Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner
Jinghai Wu; Xin Liu; Julie A. Wallace Reeser; Anthony J. Trimboli; Thierry Pecot; Gina M. Sizemore; Shan K. Naidu; Soledad A. Fernandez; Lianbo Yu; Michael Hallett; Morag Park; Gustavo W. Leone; Blake E. Hildreth; Michael C. Ostrowski
Mol Cancer Res molcanres.0960.2021.
Research Article May 9 2022
MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2 Associated Cell Adhesion
Saravanakumar Marimuthu; Imayavaramban Lakshmanan; Sakthivel Muniyan; Shailendra K. Gautam; Rama Krishna Nimmakayala; Sanchita Rauth; Pranita Atri; Ashu Shah; Namita Bhyravbhatla; Kavita Mallya; Paul M. Grandgenett; Michael A. Hollingsworth; Kaustubh Datta; Maneesh Jain; Moorthy P. Ponnusamy; Surinder K. Batra
Mol Cancer Res molcanres.0888.2021.
Research Article May 9 2022
Pan-cancer HLA Gene-mediated Tumor Immunogenicity and Immune Evasion
Mol Cancer Res molcanres.MCR-21-0886-A.2021.
Research Article May 4 2022
PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival
Mol Cancer Res (2022)
Research Article May 4 2022
Redefining CD56 as a Biomarker and Therapeutic Target in Multiple Myeloma
Francesca Cottini; Jose Rodriguez; Tiffany Hughes; Nidhi Sharma; Ling Guo; Gerard Lozanski; Bei Liu; Emanuele Cocucci; Yiping Yang; Don Benson
Mol Cancer Res (2022)
Research Article May 4 2022
T-Cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62
Colin J. Daniel; Carl Pelz; Xiaoyan Wang; Michael W. Munks; Aaron Ko; Dhaarini Murugan; Sarah A. Byers; Eleonora Juarez; Karyn L. Taylor; Guang Fan; Lisa M. Coussens; Jason M. Link; Rosalie C. Sears
Mol Cancer Res (2022)
Research Article May 4 2022
Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis
Minjung Kim; Ngoc T. Vu; Xue Wang; Gamze B. Bulut; Min-Hsuan Wang; Cora Uram-Tuculescu; Raghavendra Pillappa; Sungjune Kim; Charles E. Chalfant
Mol Cancer Res (2022)
Research Article May 4 2022
Multi-omics Profiling Shows BAP1 Loss Is Associated with Upregulated Cell Adhesion Molecules in Uveal Melanoma
Usman Baqai; Timothy J. Purwin; Nelisa Bechtel; Vivian Chua; Anna Han; Edward J. Hartsough; Jeffim N. Kuznetsoff; J. William Harbour; Andrew E. Aplin
Mol Cancer Res (2022)
Research Article May 4 2022
Midkine promotes metastasis and therapeutic resistance via mTOR/RPS6 in uveal melanoma
Margarete M. Karg; Lukas John; Nasrin Refaian; Christian Buettner; Tanja Rottmar; Jonas Sommer; Barbara Bock; Yazid J. Resheq; Bruce R. Ksander; Ludwig M. Heindl; Andreas Mackensen; Jacobus J. Bosch
Mol Cancer Res molcanres.MCR-20-0692-E.2020.
Research Article May 3 2022
Combinatorial Treatment with Poly(ADP-ribose) Polymerase-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth Through Fos-Driven Changes in Gene Expression
Mol Cancer Res molcanres.0111.2022.
Research Article May 3 2022
Exploiting dependence of castration-resistant prostate cancer on the arginine vasopressin signaling axis by repurposing vaptans
Mol Cancer Res molcanres.0927.2021.
Research Article April 26 2022
KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer
Seo-Hyun Choi; Jin K. Kim; Chin-Tung Chen; Chao Wu; Michael R. Marco; Francisco M. Barriga; Kevin O'Rourke; Raphael Pelossof; Xuan Qu; Qing Chang; Elisa de Stanchina; Jinru Shia; J. Joshua Smith; Francisco Sanchez-Vega; Julio Garcia-Aguilar
Mol Cancer Res (2022)
Research Article April 26 2022
Templated Insertions Are Associated Specifically with BRCA2 Deficiency and Overall Survival in Advanced Ovarian Cancer
Grace Moore; Rahul Majumdar; Simon N. Powell; Atif J. Khan; Nils Weinhold; Shen Yin; Daniel S. Higginson
Mol Cancer Res (2022)
Research Article April 26 2022
EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal
Haojie Li; Xuhong Fu; Junjie Zhao; Chen Li; Lingmeng Li; Peiyan Xia; Jianping Guo; Wenyi Wei; Rong Zeng; Jiarui Wu; Yihong Sun; Liyu Huang; Xuefei Wang
Mol Cancer Res (2022)
Research Article April 20 2022
mTOR Inhibition and T-DM1 in HER2-Positive Breast Cancer
David Casadevall; Anna Hernández-Prat; Sara García-Alonso; Oriol Arpí-Llucià; Silvia Menéndez; Mengjuan Qin; Cristina Guardia; Beatriz Morancho; Francisco Javier Sánchez-Martín; Sandra Zazo; Elena Gavilán; Mohammad A. Sabbaghi; Pilar Eroles; Juan Miguel Cejalvo; Ana Lluch; Federico Rojo; Atanasio Pandiella; Ana Rovira; Joan Albanell
Mol Cancer Res (2022)
Research Article April 20 2022
VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer
Ninu Poulose; Nicholas Forsythe; Adam Polonski; Gemma Gregg; Sarah Maguire; Marc Fuchs; Sarah Minner; Guido Sauter; Simon S. McDade; Ian G. Mills
Mol Cancer Res (2022)
Research Article April 20 2022
BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing
Mol Cancer Res (2022)
Research Article April 20 2022
DNA-PK Inhibition and Radiation Promote Antitumoral Immunity through RNA Polymerase III in Pancreatic Cancer
Weiwei Wang; Matthew T. McMillan; Xinyi Zhao; Zhuwen Wang; Long Jiang; David Karnak; Fatima Lima; Joshua D. Parsels; Leslie A. Parsels; Theodore S. Lawrence; Timothy L. Frankel; Meredith A. Morgan; Michael D. Green; Qiang Zhang
Mol Cancer Res (2022)
Research Article April 20 2022
Therapeutic Targeting of Stromal-Tumor HGF-MET Signaling in an Organotypic Triple-Negative Breast Tumor Model
Sunil Singh; Astha Lamichhane; Pouria Rafsanjani Nejad; Jacob Heiss; Hannah Baumann; Ravindra Gudneppanavar; Nic D. Leipzig; Michael Konopka; Gary D. Luker; Hossein Tavana
Mol Cancer Res (2022)
Research Article April 20 2022
The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling
Mol Cancer Res (2022)
Research Article April 6 2022
Transcriptome Profiling of ADAR1 Targets in Triple-Negative Breast Cancer Cells Reveals Mechanisms for Regulating Growth and Invasion
Allison R. Baker; Christos Miliotis; Julia Ramírez-Moya; Talia Marc; Ioannis S. Vlachos; Pilar Santisteban; Frank J. Slack
Mol Cancer Res (2022)
Research Article April 6 2022
Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma
E. John Tokarsky; Jesse C. Crow; Lillian M. Guenther; John Sherman; Cenny Taslim; Gabriela Alexe; Kathleen I. Pishas; Galen Rask; Blake S. Justis; Ana Kasumova; Kimberly Stegmaier; Stephen L. Lessnick; Emily R. Theisen
Mol Cancer Res (2022)
Research Article April 6 2022
Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity
Mia Han; Bianca Nguyen; Jack Y. Lee; Erica Browning; Jun Zhang; Anandaroop Mukhopadhyay; Ravindra Gujar; Jon Salazar; Reneta Hermiz; Lauren Svenson; Annah S. Rolig; William L. Redmond; Alain P. Algazi; Adil I. Daud; David A. Canton; Christopher G. Twitty
Mol Cancer Res (2022)
Research Article April 6 2022
Liver Endothelium Promotes HER3-Mediated Cell Survival in Colorectal Cancer with Wild-Type and Mutant KRAS
Moeez Rathore; Wei Zhang; Michel'le Wright; Rajat Bhattacharya; Fan Fan; Ali Vaziri-Gohar; Jordan Winter; Zhenghe Wang; Sanford D. Markowitz; Joseph Willis; Lee M. Ellis; Rui Wang
Mol Cancer Res (2022)
Research Article April 6 2022
Origins and Timing of Emerging Lesions in Advanced Renal Cell Carcinoma
Andrew Wallace; Sima P. Porten; Amy A. Lo; Daniel Oreper; Nicolas Lounsbury; Charles Havnar; Ximo Pechuan-Jorge; Oliver A. Zill; Maxwell V. Meng
Mol Cancer Res (2022)
Research Article April 6 2022
Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers
Pamela J. Maxwell; Melanie McKechnie; Christopher W. Armstrong; Judith M. Manley; Chee Wee Ong; Jenny Worthington; Ian G. Mills; Daniel B. Longley; James P. Quigley; Amina Zoubeidi; Johann S. de Bono; Elena Deryugina; Melissa J. LaBonte; David J.J. Waugh
Mol Cancer Res (2022)
Article Commentary April 6 2022
Unlocking the Mysteries of Lobular Breast Cancer Biology Needs the Right Combination of Preclinical Models
Mol Cancer Res (2022)
Research Article March 17 2022
Diurnal Expression of PD-1 on Tumor-Associated Macrophages Underlies the Dosing Time-Dependent Antitumor Effects of the PD-1/PD-L1 Inhibitor BMS-1 in B16/BL6 Melanoma-Bearing Mice
Akito Tsuruta; Yuki Shiiba; Naoya Matsunaga; Marina Fujimoto; Yuya Yoshida; Satoru Koyanagi; Shigehiro Ohdo
Mol Cancer Res (2022)
Research Article March 17 2022
Suppression of SIN3A by miR-183 Promotes Breast Cancer Metastasis
Mackenzie L. Davenport; Mara R. Davis; Baylea N. Davenport; David K. Crossman; Aaron Hall; Jason Pike; Shuko Harada; Douglas R. Hurst; Mick D. Edmonds
Mol Cancer Res (2022)
Research Article March 16 2022
Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
Masum Rahman; Ian Olson; Moustafa Mansour; Lucas P. Carlstrom; Rujapope Sutiwisesak; Rehan Saber; Karishma Rajani; Arthur E. Warrington; Adam Howard; Mark Schroeder; Sisi Chen; Paul A. Decker; Eliot F. Sananikone; Yi Zhu; Tamar Tchkonia; Ian F. Parney; Sandeep Burma; Desmond Brown; Moses Rodriguez; Jann N. Sarkaria; James L. Kirkland; Terry C. Burns
Mol Cancer Res (2022)
Research Article March 16 2022
Targeting Metabolic Adaptations in the Breast Cancer–Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy
Qianying Zuo; Ayca Nazli Mogol; Yu-Jeh Liu; Ashlie Santaliz Casiano; Christine Chien; Jenny Drnevich; Ozan Berk Imir; Eylem Kulkoyluoglu-Cotul; Nicole Hwajin Park; David J. Shapiro; Ben Ho Park; Yvonne Ziegler; Benita S. Katzenellenbogen; Evelyn Aranda; John D. O'Neill; Akshara Singareeka Raghavendra; Debu Tripathy; Zeynep Madak Erdogan
Mol Cancer Res (2022)
Research Article March 16 2022
EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity
Kellie Lucken; Laura O'Regan; Jene Choi; Josephina Sampson; Sarah L. Pashley; Richard Bayliss; Sam Khan; Andrew M. Fry
Mol Cancer Res (2022)
Research Article March 16 2022
Constitutive β-Catenin Overexpression Represses Lncrna MIR100HG Transcription via HDAC6-Mediated Histone Modification in Colorectal Cancer
Mol Cancer Res (2022)
Research Article February 21 2022
Vitamin D Receptor Activation Attenuates Hippo Pathway Effectors and Cell Survival in Metastatic Neuroblastoma
Yagnesh Ladumor; Bo Kyung Alex Seong; Robin Hallett; Ivette Valencia-Sama; Teresa Adderley; Yingying Wang; Lynn Kee; Alexander Gont; David R. Kaplan; Meredith S. Irwin
Mol Cancer Res (2022)
Research Article February 17 2022
Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers
Zhengbo Hu; Ramya Viswanathan; Hui Cheng; Jianghong Chen; Xinping Yang; Angel Huynh; Paul Clavijo; Yi An; Yvette Robbins; Christopher Silvin; Clint Allen; Pinar Ormanoglu; Scott Martin; Shaleeka Cornelius; Anthony Saleh; Zhong Chen; Carter Van Waes; Ethan L. Morgan
Mol Cancer Res (2022)
Research Article January 1 2016
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations
Tyler M Foley; Susan N. Payne; Cheri A. Pasch; Alex E. Yueh; Dana R Van De Hey; Demetra P Korkos; Linda Clipson; Molly E Maher; Kristina A. Matkowskyj; Michael A. Newton; Dustin A. Deming
Mol Cancer Res molcanres.0256.2016.
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