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Research Article March 29 2023
ADAM Metallopeptidase Domain 12 Facilitates Colorectal Cancer Progression by Inhibiting Hippo Signaling Pathway Activity
Mol Cancer Res (2023)
Research Article March 29 2023
JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer
Bianca Cioni; Silvia Ratti; Annamaria Piva; Irene Tripodi; Matteo Milani; Francesca Menichetti; Tiziana Langella; Laura Botti; Loris De Cecco; Claudia Chiodoni; Daniele Lecis; Mario P. Colombo
Mol Cancer Res (2023)
Research Article March 29 2023
Targeting Unc51-like Autophagy Activating Kinase 1 (ULK1) Overcomes Adaptive Drug Resistance in Acute Myelogenous Leukemia
Seemana Bhattacharya; Sujan Piya; Huaxian Ma; Priyanka Sharma; Qi Zhang; Natalia Baran; Vivian R. Ruvolo; Teresa McQueen; R. Eric Davis; Rasoul Pourebrahim; Marina Konopleva; Hagop Kantarjian; Nicholas D. P. Cosford; Michael Andreeff; Gautam Borthakur
Mol Cancer Res (2023)
Research Article March 28 2023
Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia
William M. Yashar; Brittany M. Curtiss; Daniel J. Coleman; Jake VanCampen; Garth Kong; Jommel Macaraeg; Joseph Estabrook; Emek Demir; Nicola Long; Daniel Bottomly; Shannon K. McWeeney; Jeffrey W. Tyner; Brian J. Druker; Julia E. Maxson; Theodore P. Braun
Mol Cancer Res MCR-22-0745.
Research Article March 28 2023
BLEACH&STAIN 15-marker multiplexed imaging in 3098 human carcinomas reveals 6 major PD-L1-driven immune phenotypes with distinct spatial orchestration
Elena Bady; Katharina Moeller; Tim Mandelkow; Jonas B. Raedler; Cheng Yang; Julia Ebner; Magalie C.J. Lurati; Ronald Simon; Eik Vettorazzi; Franziska Buescheck; Andreas M. Luebke; David Dum; Anne Menz; Guido Sauter; Doris Hoeflmayer; Soeren Weidemann; Christoph Fraune; Ria Uhlig; Christian Bernreuther; Frank Jacobsen; Till S. Clauditz; Waldemar Wilczak; Eike Burandt; Stefan Steurer; Sarah Minner; Maximilian Lennartz; Niclas C. Blessin
Mol Cancer Res MCR-22-0593.
Research Article March 24 2023
Downregulation of BASP1 promotes temozolomide resistance in gliomas via epigenetic activation of the FBXO32/NF-κB/MGMT axis
Xinyi Liao; Ziwen Li; Haiqing Zheng; Wanying Qian; Shuxia Zhang; Suwen Chen; Xincheng Li; Miaoling Tang; Yingru Xu; Ruyuan Yu; Man Li; Libing Song; Jun Li
Mol Cancer Res MCR-22-1012.
Research Article March 24 2023
Non-essential amino acid availability influences proteostasis and breast cancer cell survival during proteotoxic stress
Mol Cancer Res MCR-22-0843.
Research Article March 20 2023
USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis
Mol Cancer Res MCR-22-0552.
Research Article March 17 2023
UBE2C-mediated autophagy inhibition via ubiquitination of SIRT1 contributes to endometrial cancer progression
Rong Zhao; Yan Liu; Ziwei Wang; Jun Zhang; Wei Zhang; Xing Zhou; Sevjid Tsedendorj; Amarsanaa Enkhtur; Dilu Feng; Hongbo Wang
Mol Cancer Res MCR-22-0825.
Research Article March 17 2023
FOXA1 reprogramming dictates retinoid X receptor response in ESR1 mutant breast cancer
Yang Wu; Zheqi Li; Abdalla M. Wedn; Allison N. Casey; Daniel Brown; Shalini V. Rao; Soleilmane Omarjee; Jagmohan Hooda; Jason S. Carroll; Jason Gertz; Jennifer M. Atkinson; Adrian V. Lee; Steffi Oesterreich
Mol Cancer Res MCR-22-0516.
Research Article March 15 2023
Interdependence of SS18-SSX-driven YAP1 and β-catenin activation in synovial sarcoma
Ilka Isfort; Ruth Berthold; Lorena Heinst; Eva Wardelmann; Olle Larsson; Marcel Trautmann; Wolfgang Hartmann
Mol Cancer Res MCR-22-0588.
Research Article March 8 2023
MYC/Glutamine Dependency Is a Therapeutic Vulnerability in Pancreatic Cancer with Deoxycytidine Kinase Inactivation-Induced Gemcitabine Resistance
Suman Dash; Takeshi Ueda; Akiyoshi Komuro; Hisayuki Amano; Masahiko Honda; Masahito Kawazu; Hitoshi Okada
Mol Cancer Res (2023)
Research Article March 8 2023
The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma
Sebastiaan M. Schieven; Joleen J.H. Traets; Alex v. Vliet; Martijn v. Baalen; Ji-Ying Song; Marcos Da Silva Guimaraes; Thomas Kuilman; Daniel S. Peeper
Mol Cancer Res (2023)
Research Article March 1 2023
Exosomal lincROR Promotes Docetaxel Resistance in Prostate Cancer through a β-catenin/HIF1α Positive Feedback Loop
Mol Cancer Res (2023)
Research Article February 22 2023
BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification
Sarah E. Barnett; Jenna Kenyani; Martina Tripari; Zohra Butt; Rudi Grosman; Francesca Querques; Liam Shaw; Luisa C. Silva; Zoe Goate; Stefan J. Marciniak; Doris M. Rassl; Richard Jackson; Lu-Yun Lian; Peter W. Szlosarek; Joseph J. Sacco; Judy M. Coulson
Mol Cancer Res (2023)
Research Article February 22 2023
Bone Marrow Mesenchymal Stem Cells Induce Metabolic Plasticity in Estrogen Receptor–Positive Breast Cancer
Johanna M. Buschhaus; Shrila Rajendran; Siyi Chen; Bryan L. Wharram; Avinash S. Bevoor; Alyssa C. Cutter; Brock A. Humphries; Tanner H. Robison; Alex P. Farfel; Gary D. Luker
Mol Cancer Res (2023)
Research Article February 22 2023
Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling
Dandan Li; Anne M. Miermont; Rushikesh Sable; Humair S. Quadri; Lesley A. Mathews Griner; Scott E. Martin; Taivan Odzorig; Soumita De; Marc Ferrer; Astin S. Powers; Stephen M. Hewitt; Udo Rudloff
Mol Cancer Res (2023)
Research Article February 15 2023
Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma
Jessica Limberg; Caitlin E. Egan; Katherine D. Gray; Mandeep Singh; Zachary Loewenstein; Yanping Yang; Maria Cristina Riascos; Hala Al Asadi; Parima Safe; Steve El Eshaky; Heng Liang; Timothy M. Ullmann; Weibin Wang; Wei Li; Tuo Zhang; Jenny Xiang; Dessislava Stefanova; Moonsoo M. Jin; Rasa Zarnegar; Thomas J. Fahey, III; Irene M. Min
Mol Cancer Res (2023)
Review Article February 15 2023
Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment
Edgar Petrosyan; Jawad Fares; Luis G. Fernandez; Ragini Yeeravalli; Crismita Dmello; Joseph T. Duffy; Peng Zhang; Catalina Lee-Chang; Jason Miska; Atique U. Ahmed; Adam M. Sonabend; Irina V. Balyasnikova; Amy B. Heimberger; Maciej S. Lesniak
Mol Cancer Res (2023)
Research Article January 26 2023
Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response
Claire M Storey; Mohamed Altai; Mesude Bicak; Darren R Veach; Katharina Lückerath; Gabriel Adrian; Michael R McDevitt; Teja Kalidindi; Julie E Park; Ken Herrmann; Diane Abou; Wahed Zedan; Norbert Peekhaus; Robert J Klein; Robert Damoiseaux; Steven M Larson; Hans Lilja; Daniel Thorek; David Ulmert
Mol Cancer Res (2023)
Research Article January 26 2023
TBX3 Promotes Cervical Cancer Proliferation and Migration via HPV E6 and E7 Signaling
Saif F. Khan; Carly A. Burmeister; David J. Scott; Musalula Sinkala; Amsha Ramburan; Hue-Tsi Wu; Georgia Schäfer; Arieh A. Katz; Sharon Prince
Mol Cancer Res (2023)
Research Article January 18 2023
Evolutionary Characteristics and Immunologic Divergence of Lung and Brain Metastasis Lesions in NSCLC
Tongji Xie; Zhenghao Liu; Yan Li; Shouzheng Wang; Yixin Zhai; Fei Teng; Xuezhi Hao; Yan Wang; Hongyu Wang; Xin Zhang; Xi Wu; Jianming Ying; Junling Li; Ye Zhang; Yuefei Deng; Puyuan Xing
Mol Cancer Res (2023)
Research Article January 18 2023
Targeting ULK1 Decreases IFNγ-Mediated Resistance to Immune Checkpoint Inhibitors
Sarah E. Fenton; Markella Zannikou; Liliana Ilut; Mariafausta Fischietti; Chunni Ji; Chidera V. Oku; Curt M. Horvath; I. Caroline Le Poole; Marcus Bosenberg; Elizabeth T. Bartom; Masha Kocherginsky; Leonidas C. Platanias; Diana Saleiro
Mol Cancer Res (2023)
Brief Report January 13 2023
Malignant Progression of an Ancestral Bone Marrow Clone Harboring a CIC-NUTM2A Fusion in Isolated Myeloid Sarcoma
Jennifer L. Kamens; Jinjun Dang; Timothy I. Shaw; Alexander M. Gout; Scott Newman; Kohei Hagiwara; Amelia M.R. Smith; Alyssa N. Obermayer; Sarah Aldridge; Jing Ma; Yang Zhang; Gang Wu; Vasiliki Leventaki; Teresa Santiago; Susana Raimondi; Joy Nakitandwe; Alberto Pappo; Chunliang Li; Jinghui Zhang; Tanja A. Gruber
Mol Cancer Res (2023)
Research Article January 13 2023
Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer
Gio Fidelito; David P. De Souza; Birunthi Niranjan; William De Nardo; Shivakumar Keerthikumar; Kristin Brown; Renea A. Taylor; Matthew J. Watt
Mol Cancer Res (2023)
Review Article January 13 2023
BRAF-Driven Pancreatic Cancer: Prevalence, Molecular Features, and Therapeutic Opportunities
Mol Cancer Res (2023)
Research Article January 1 2016
Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations
Tyler M Foley; Susan N. Payne; Cheri A. Pasch; Alex E. Yueh; Dana R Van De Hey; Demetra P Korkos; Linda Clipson; Molly E Maher; Kristina A. Matkowskyj; Michael A. Newton; Dustin A. Deming
Mol Cancer Res molcanres.0256.2016.
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