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Volume 7, Issue 7
1 July 2009
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    Formation of retraction fibres by serum-starved human breast cancer MDA-MB-231 cells in response to stimulation with lysophosphatidic acid. Fluorescent phalloidin was used to visualize the cytoskeleton; cell nuclei (blue) were stained with Hoechst. For details see the article by Li and colleagues on page 1064.
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ISSN 1541-7786
EISSN 1557-3125

Journal Archive

Molecular Cancer Research (2002-Present; volumes 1-current)

(ISSN 0008-5472) Published monthly since November, 2002.

Cell Growth & Differentiation (1990-2002; volumes 1-13)

(ISSN 1044-9523) Published monthly 1990- September, 2002.

Table of Contents

Subject Reviews

DNA Repair and Resistance of Gliomas to Chemotherapy and Radiotherapy
Guido Frosina
View articletitled, DNA Repair and Resistance of Gliomas to Chemotherapy and Radiotherapy
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Therapeutic Inhibition of the Epidermal Growth Factor Receptor in High-Grade Gliomas: Where Do We Stand?
Georg Karpel-Massler; Ursula Schmidt; Andreas Unterberg; Marc-Eric Halatsch
View articletitled, Therapeutic Inhibition of the Epidermal Growth Factor Receptor in High-Grade Gliomas: Where Do We Stand?
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Angiogenesis, Metastasis, and the Cellular Microenvironment

Omega-3 Polyunsaturated Fatty Acids Down-Modulate CXCR4 Expression and Function in MDA-MB-231 Breast Cancer Cells
Jeffrey D. Altenburg; Rafat A. Siddiqui
View articletitled, Omega-3 Polyunsaturated Fatty Acids Down-Modulate CXCR4 Expression and Function in MDA-MB-231 Breast Cancer Cells
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Hsp90 Is an Essential Regulator of EphA2 Receptor Stability and Signaling: Implications for Cancer Cell Migration and Metastasis
Balasubramaniam Annamalai; Xueguang Liu; Udhayakumar Gopal; Jennifer S. Isaacs
View articletitled, Hsp90 Is an Essential Regulator of EphA2 Receptor Stability and Signaling: Implications for Cancer Cell Migration and Metastasis
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CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma–Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells
Sarah M. Eck; Anik L. Côté; William D. Winkelman; Constance E. Brinckerhoff
View articletitled, CXCR4 and Matrix Metalloproteinase-1 Are Elevated in Breast Carcinoma–Associated Fibroblasts and in Normal Mammary Fibroblasts Exposed to Factors Secreted by Breast Cancer Cells
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Matrix Protein CCN1 Is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis
Carrie A. Franzen; Chih-Chiun Chen; Viktor Todorović; Vladislava Juric; Ricardo I. Monzon; Lester F. Lau
View articletitled, Matrix Protein CCN1 Is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis
Supplementary data
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Vascular Caveolin Deficiency Supports the Angiogenic Effects of Nitrite, a Major End Product of Nitric Oxide Metabolism in Tumors
Françoise Frérart; Irina Lobysheva; Bernard Gallez; Chantal Dessy; Olivier Feron
View articletitled, Vascular Caveolin Deficiency Supports the Angiogenic Effects of Nitrite, a Major End Product of Nitric Oxide Metabolism in Tumors
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β-Arrestin/Ral Signaling Regulates Lysophosphatidic Acid–Mediated Migration and Invasion of Human Breast Tumor Cells
Timothy T. Li; Mistre Alemayehu; Adel I. Aziziyeh; Cynthia Pape; Macarena Pampillo; Lynne-Marie Postovit; Gordon B. Mills; Andy V. Babwah; Moshmi Bhattacharya
View articletitled, β-Arrestin/Ral Signaling Regulates Lysophosphatidic Acid–Mediated Migration and Invasion of Human Breast Tumor Cells
Supplementary data
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Targeting of Tumor Blood Vessels: A Phage-Displayed Tumor-Homing Peptide Specifically Binds to Matrix Metalloproteinase-2-Processed Collagen IV and Blocks Angiogenesis In vivo
Jan Mueller; Florian C. Gaertner; Birgit Blechert; Klaus-Peter Janssen; Markus Essler
View articletitled, Targeting of Tumor Blood Vessels: A Phage-Displayed Tumor-Homing Peptide Specifically Binds to Matrix Metalloproteinase-2-Processed Collagen IV and Blocks Angiogenesis <em>In vivo</em>
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Cell Cycle, Cell Death, and Senescence

Potentiation of Cannabinoid-Induced Cytotoxicity in Mantle Cell Lymphoma through Modulation of Ceramide Metabolism
Kristin Gustafsson; Birgitta Sander; Jacek Bielawski; Yusuf A. Hannun; Jenny Flygare
View articletitled, Potentiation of Cannabinoid-Induced Cytotoxicity in Mantle Cell Lymphoma through Modulation of Ceramide Metabolism
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DNA Damage and Cellular Stress Responses

Elevated Poly-(ADP-Ribose)-Polymerase Activity Sensitizes Retinoblastoma-Deficient Cells to DNA Damage–Induced Necrosis
Huiping Liu; James R. Knabb; Benjamin T. Spike; Kay F. Macleod
View articletitled, Elevated Poly-(ADP-Ribose)-Polymerase Activity Sensitizes Retinoblastoma-Deficient Cells to DNA Damage–Induced Necrosis
Supplementary data
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PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2
Fan Zhang; Qiang Fan; Keqin Ren; Paul R. Andreassen
View articletitled, PALB2 Functionally Connects the Breast Cancer Susceptibility Proteins BRCA1 and BRCA2
Supplementary data
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Signaling and Regulation

Parathyroid Hormone-Related Protein Regulates Cell Survival Pathways via Integrin α6β4-Mediated Activation of Phosphatidylinositol 3-Kinase/Akt Signaling
Vandanajay Bhatia; Ramanjaneya V. Mula; Nancy L. Weigel; Miriam Falzon
View articletitled, Parathyroid Hormone-Related Protein Regulates Cell Survival Pathways via Integrin α<sub>6</sub>β<sub>4</sub>-Mediated Activation of Phosphatidylinositol 3-Kinase/Akt Signaling
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Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
Adam Denley; Marco Gymnopoulos; Sohye Kang; Christina Mitchell; Peter K. Vogt
View articletitled, Requirement of Phosphatidylinositol(3,4,5)Trisphosphate in Phosphatidylinositol 3-Kinase-Induced Oncogenic Transformation
Supplementary data
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Nuclear Factor-κB Inhibition by Parthenolide Potentiates the Efficacy of Taxol in Non–Small Cell Lung Cancer In vitro and In vivo
Dianliang Zhang; Lin Qiu; Xianqing Jin; Zhenhua Guo; Chunbao Guo
View articletitled, Nuclear Factor-κB Inhibition by Parthenolide Potentiates the Efficacy of Taxol in Non–Small Cell Lung Cancer <em>In vitro</em> and <em>In vivo</em>
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An Erythropoietin Autocrine/Paracrine Axis Modulates the Growth and Survival of Human Prostate Cancer Cells
Jee-Yeong Jeong; Gerta Hoxhaj; Amanda L. Socha; Arthur J. Sytkowski; Laurie Feldman
View articletitled, An Erythropoietin Autocrine/Paracrine Axis Modulates the Growth and Survival of Human Prostate Cancer Cells
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Cyclooxygenase-2 Up-Regulates Ataxia Telangiectasia and Rad3 Related through Extracellular Signal-Regulated Kinase Activation
Young Mee Kim; Eun Jung Lee; Soo-Yeon Park; Kwan Ho Cho; Joo Young Kim; Hongryull Pyo
View articletitled, Cyclooxygenase-2 Up-Regulates Ataxia Telangiectasia and Rad3 Related through Extracellular Signal-Regulated Kinase Activation
Supplementary data
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p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor–Induced Bα (Nur77) in Pancreatic Cancer Cells
Syng-Ook Lee; Sudhakar Chintharlapalli; Shengxi Liu; Sabitha Papineni; Sung Dae Cho; Kyungsil Yoon; Stephen Safe
View articletitled, p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor–Induced Bα (Nur77) in Pancreatic Cancer Cells
Supplementary data
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Id1 Is Down-Regulated by Hepatocyte Growth Factor via ERK-Dependent and ERK-Independent Signaling Pathways, Leading to Increased Expression of p16INK4a in Hepatoma Cells
Kazutaka Ushio; Tomio Hashimoto; Naomi Kitamura; Toshiaki Tanaka
View articletitled, Id1 Is Down-Regulated by Hepatocyte Growth Factor via ERK-Dependent and ERK-Independent Signaling Pathways, Leading to Increased Expression of p16<sup>INK4a</sup> in Hepatoma Cells
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