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1 May 2018
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Cover Image
Cover Image
ABOUT THE COVER
The cover image depicts results of a genome-wide siRNA screen to obtain a systematic assessment of genes integrated in the IRE1α-XBP1 branch of the unfolded protein response (UPR). The dot plot illustrates the average Z-scores of normalized luminescence readings for each targeted gene. Green and black colors represent the non-targeting siRNA and the non-induced controls, respectively. The entire siRNA library is colored in blue with candidate genes highlighted in yellow. Red and grey dash line represents cutoff Z-score of -1.5 and -0.5. For more information, please see the Rapid Impact by Yang and colleagues beginning on page 745. - PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkEditorial Board
ISSN 1541-7786
EISSN 1557-3125
Molecular Cancer Research
Table of Contents
Highlights
Rapid Impact
Cell Death and Survival
Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma
Jonas Blaes; Carina M. Thomé; Philipp-Niclas Pfenning; Petra Rübmann; Felix Sahm; Antje Wick; Theresa Bunse; Torsten Schmenger; Jaromir Sykora; Andreas von Deimling; Benedikt Wiestler; Christian Merz; Manfred Jugold; Uwe Haberkorn; Amir Abdollahi; Jürgen Debus; Christian Gieffers; Claudia Kunz; Martin Bendszus; Michael Kluge; Michael Platten; Harald Fricke; Wolfgang Wick; Dieter Lemke
Antisecretory Factor–Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma
Shirin Ilkhanizadeh; Hanna Sabelström; Yekaterina A. Miroshnikova; Aaron Frantz; Wen Zhu; Aurora Idilli; Jon N. Lakins; Christin Schmidt; David A. Quigley; Trenten Fenster; Edith Yuan; Jacqueline R. Trzeciak; Supna Saxena; Olle R. Lindberg; Janna K. Mouw; Jason A. Burdick; Sergey Magnitsky; Mitchel S. Berger; Joanna J. Phillips; Daniele Arosio; Dandan Sun; Valerie M. Weaver; William A. Weiss; Anders I. Persson
Chromatin, Epigenetics, and RNA Regulation
Genomics
Landscape of Tumor Mutation Load, Mismatch Repair Deficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers
Mohamed E. Salem; Alberto Puccini; Axel Grothey; Derek Raghavan; Richard M. Goldberg; Joanne Xiu; W. Michael Korn; Benjamin A. Weinberg; Jimmy J. Hwang; Anthony F. Shields; John L. Marshall; Philip A. Philip; Heinz-Josef Lenz
Author Choice
Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma
Rebecca C. Arend; Angelina I. Londoño; Allison M. Montgomery; Haller J. Smith; Zachary C. Dobbin; Ashwini A. Katre; Alba Martinez; Eddy S. Yang; Ronald D. Alvarez; Warner K. Huh; Kerri S. Bevis; J. Michael Straughn, Jr; Jacob M. Estes; Lea Novak; David K. Crossman; Sara J. Cooper; Charles N. Landen; Charles A. Leath, III
Oncogenes and Tumor Suppressors
Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK–Induced ETS1 Transcriptional Activity
Victoria Peyret; Magalí Nazar; Mariano Martín; Amado A. Quintar; Elmer A. Fernandez; Romina C. Geysels; Cesar S. Fuziwara; María M. Montesinos; Cristina A. Maldonado; Pilar Santisteban; Edna T. Kimura; Claudia G. Pellizas; Juan P. Nicola; Ana M. Masini-Repiso
Signal Transduction
Author Choice
Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models
Laura W. Bowers; Emily L. Rossi; Shannon B. McDonell; Steven S. Doerstling; Subreen A. Khatib; Claire G. Lineberger; Jody E. Albright; Xiaohu Tang; Linda A. deGraffenried; Stephen D. Hursting
Journal Archive
Molecular Cancer Research
(2002-Present; volumes 1-current)Published monthly since November, 2002.
(ISSN 0008-5472)
Cell Growth & Differentiation
(1990-2002; volumes 1-13)Published monthly 1990- September, 2002.
(ISSN 1044-9523)
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