Skip Nav Destination
Issues
1 February 2012
-
Cover Image
Cover Image
The E6 oncoprotein from high-risk papilloma viruses is required for the development of several types of cancers, such as those of the cervix, larynx, and skin. E6 exerts its oncogenic effects through the deregulation of several cellular pathways. By using a transgenic mouse model expressing the E6 oncoprotein in skin, it was found by immunofluorescence that this viral protein gradually induces the accumulation of β-catenin in the nucleus of epithelial cells, suggesting that E6 is able to induce canonical Wnt pathway. For further details, please see the article by Bonilla-Delgado and coworkers on page 250 in this issue.Close Modal - PDF Icon PDF LinkTable of Contents
ISSN 1541-7786
EISSN 1557-3125
Highlights
Angiogenesis, Metastasis, and the Cellular Microenvironment
Cancer Genes and Genomics
Caveolin-1 Upregulation Contributes to c-Myc–Induced High-Grade Prostatic Intraepithelial Neoplasia and Prostate Cancer
Guang Yang; Alexei A. Goltsov; Chengzhen Ren; Shinji Kurosaka; Kohei Edamura; Richard Logothetis; Francesco J. DeMayo; Patricia Troncoso; Jorge Blando; John DiGiovanni; Timothy C. Thompson
DNA Damage and Cellular Stress Responses
Notch Signaling Modulates Hypoxia-Induced Neuroendocrine Differentiation of Human Prostate Cancer Cells
Giovanna Danza; Claudia Di Serio; Fabiana Rosati; Giuseppe Lonetto; Niccolò Sturli; Doreen Kacer; Antonio Pennella; Giuseppina Ventimiglia; Riccardo Barucci; Annamaria Piscazzi; Igor Prudovsky; Matteo Landriscina; Niccolò Marchionni; Francesca Tarantini
Signaling and Regulation
The E6 Oncoprotein from HPV16 Enhances the Canonical Wnt/β-Catenin Pathway in Skin Epidermis In Vivo
José Bonilla-Delgado; Gülay Bulut; Xuefeng Liu; Enoc M. Cortés-Malagón; Richard Schlegel; Catalina Flores-Maldonado; Rubén G. Contreras; Sang-Hyuk Chung; Paul F. Lambert; Aykut Üren; Patricio Gariglio
Advertisement