Chemokine receptors play a role in cell proliferation, migration, adhesion, as well as homing of tumor cells to their metastatic niches. A member of the chemokine family of receptor proteins, lymphotactin (XCR1), is expressed in primary and metastatic epithelial ovarian carcinoma and supports XCL1/2-induced tumor cell migration and proliferation and formation of metastasis on diaphragm and peritoneal wall. Using immunofluorescence it was demonstrated that ovarian carcinoma cell lines express XCR1. For details, see the article by Kim et al. on page 1419.