The November 2012 issue of Molecular Cancer Research represents the 10-year anniversary of the initiation of this AACR journal. I have had the honor and the privilege of serving as the Editor-in-Chief of the journal during this period of time. The successful launch and growth of the journal owes much to the outstanding editorial staff at AACR and to the Senior Editors who have given so generously of their time and expertise. The journal is proud to be a visible member of the stable of AACR journals and has benefited from working with the other AACR journals to create complementary visions and activities that span the broad spectrum of cancer research topics. As of January 1, 2013, the leadership of this journal will be turned over to the very capable hands of Dr. Karen E. Knudsen. Karen brings outstanding expertise in basic and translational cancer research to complement her energy and vision for taking the journal to the next level of success and impact. As I step down as Editor-in-Chief, I would like to express particular appreciation to Dr. Margaret Foti for her unwavering support and interest in the journal, to June Eberharter and Kelly Hadsell for their extraordinary work as Managing Editors over the years, and to Karen Quann for the outstanding job that she did in managing journal submissions every day of every month of every year. It has been my pleasure to work with all of these individuals. I would also like to express particular gratitude to Dr. Amato Giaccia, for his consistent contributions as Deputy Editor and Reviews Editor. I look forward with pride to the continued growth and success of Molecular Cancer Research under Dr. Knudsen's leadership and the new Senior Editor group that she will put into place.

Michael B. Kastan, MD, PhD


Molecular Cancer Research