Molecular and Cellular Biology

Topics in Molecular and Cellular Biology

• Expand/Collapse Section CARCINOGENESIS
  • Chemical carcinogenesis

  • Hormonal carcinogenesis

  • Carcinogen metabolism

  • Environmental carcinogenesis

  • Risk assessment

  • Premalignancy

  • Signal transduction

  • Mutagenesis

  • Reactive oxygen and carcinogenesis

  • Tumor initiation and promotion

  • Animal models of carcinogenesis

  • In vitro models of carcinogenesis

  • Tobacco

  • DNA damage and repair
• Expand/Collapse Section ONCOGENES & TUMOR SUPPRESSORS
  • Oncogenes

  • Tumor suppressor genes

  • p53

  • PTEN

  • PD-1

  • TP53

  • Kras

  • Rb and family

  • APC

  • BRCA family

  • miRNA tumor suppressors

  • Suppressors of metastasis
• Expand/Collapse Section RADIOBIOLOGY
  • Cell cycle and apoptosis in radiation responses

  • Radiation-induced DNA damage

  • Radiation and tumor microenvironment

  • Radiation-activated signaling pathways

  • Modulators of radiation response
• Expand/Collapse Section VIRAL ONCOGENESIS
  • Human tumor viruses

  • DNA tumor viruses

  • Retroviruses

  • Viral transformation and carcinogenesis

  • Host-virus interactions
• Expand/Collapse Section BIOCHEMISTRY
  • Protein/DNA interactions

  • Protein/protein interactions

  • Small molecule/DNA interactions
• Expand/Collapse Section CELL CYCLE
  • Control of cell cycle progression

  • Cell cycle checkpoints

  • Cyclins

  • CDKs and CDK inhibitors

  • Mitosis

  • Signal transduction pathways
• Expand/Collapse Section CELL DEATH AND SENESCENCE
  • Transcriptional control of apoptosis

  • Receptor-coupled signaling to apoptosis

  • Caspases

  • Effectors of apoptosis

  • Survival factors

  • Intercellular interactions in apoptosis

  • bcl-2 pathways

  • Fas/tumor necrosis factor receptor family

  • Telomeres and telomerase

  • Cellular aging and senescence

  • Necroptosis

  • Ferroptosis
• Expand/Collapse Section CELL SIGNALING
  • Growth factors

  • Receptors

  • Autocrine-paracrine signaling

  • Cell adhesion

  • Cell-cell interactions

  • Protein tyrosine kinases

  • Protein serine-threonine kinases

  • Phosphatases

  • Cytosolic adaptors and intermediate molecules

  • Guanine nucleotide binding proteins and effectors
• Expand/Collapse Section CELLULAR STRESS RESPONSES
• Expand/Collapse Section DNA DAMAGE AND REPAIR
  • DNA damage

  • Gene amplification

  • Chromosomal translocations

  • Genomic instability

  • DNA repair

  • Mechanisms of genomic alterations
• Expand/Collapse Section EPIGENETICS
  • Chromatin structure and function

  • DNA methylation

  • Epigenomics

  • Gene silencing

  • Histone Modification
• Expand/Collapse Section GENE REGULATION
  • Mechanisms of transcription

  • Promoter/enhancer analysis

  • Inducible gene expression

  • Oncogenic transcription factors

  • Transcription factor function

  • Phosphorylation and gene expression

  • Transcriptional control of cell differentiation

  • Antisense control of gene expression

  • Posttranscriptional and translational control
• Expand/Collapse Section GENOME BIOLOGY
  • Comparative transcriptomics

  • Structural genomics

  • Silencing and reactivation of gene expression

  • Non-coding RNAs & microRNAs

  • Functional genomics
• Expand/Collapse Section METABOLISM
  • Metabolic pathways

  • Metabolomics

  • Mitochondrial function

  • Warburg effect
• Expand/Collapse Section STEM CELL BIOLOGY
  • Cancer stem cells

  • Dedifferentiation

  • iPS cells

  • Mesenchymal stem cells

  • Somatic stem cells

  • Hematopoiesis