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Epidemiology and Prevention

Population-level studies that investigate the genetic and environmental risk factors of cancer and their application in disease prevention and interception

Latest in Epidemiology and Prevention
Shuo Li, Wenyuan Li et al.
Accurate diagnosis of lung cancer is important for treatment decision-making. Tumor biopsy and histological examination is the standard for determining histological lung cancer subtypes. Liquid biopsy, particularly cell-free DNA (cfDNA), has recently shown promising results in cancer detection and classification. In this ...
Nijole P. Tjader, Abigail J. Beer et al.
In breast tumors, somatic mutation frequencies in TP53 and PIK3CA vary by tumor subtype and ancestry. Emerging data suggest tumor mutation status is associated with germline variants and genetic ancestry. We aimed to identify germline variants that are associated with somatic TP53 or PIK3CA mutation status in breast ...
Gopika SenthilKumar, Aronne M. Schottstaedt et al.
Among patients with breast cancer undergoing radiotherapy, posttreatment cardiovascular disease and worsened quality of life (QoL) are leading causes of morbidity and mortality. To overcome these negative radiotherapy effects, this prospective, randomized clinical trial pilots a 12-week Stay on Track exercise and diet ...
Pierpaolo Ginefra, Helen Carrasco Hope et al.
Naïve T cells are key players in cancer immunosurveillance, even though their function declines during tumor progression. Thus, interventions capable of sustaining the quality and function of naïve T cells are needed to improve cancer immunoprevention.
Katherine Ross-Driscoll, Arrey-Takor Ayuk-Arrey et al.
Liver transplantation offers the best survival for patients with early-stage hepatocellular carcinoma (HCC). Prior studies have demonstrated disparities in transplant access; none have examined the early steps of the transplant process. We identified determinants of access to transplant referral and evaluation among ...
Daimarelys Lara, Edgar I. Alaniz-Cantú et al.
The purpose of this study was to assess the feasibility and acceptability of a mobile intervention that promotes smoking cessation and physical activity among Latinos living in the United States. Twenty Latino adults who smoked and did not meet recommended levels of physical activity were recruited using community-based ...
Yuwaraj Kadariya, Eleonora Sementino et al.
Asbestos and BAP1 germline mutations are risk factors for malignant mesothelioma (MM). While it is well accepted that amphibole asbestos is carcinogenic, the role of serpentine (chrysotile) asbestos in MM has been debated. To address this controversy, we assessed whether minimal exposure to chrysotile could significantly ...
Shama Karanth, Oyomoare L. Osazuwa-Peters et al.
This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients with ovarian cancer. This retrospective cohort study used the Surveillance, Epidemiology, and End ...
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