Immunotherapy Collection

Editors of the AACR journals reviewed the published content to identify hot topics across the entire portfolio of eight journals. The collection is focused on immunotherapy and consists of articles selected based on a number of key metrics, such as usage and citations. We hope that you enjoy this complimentary cross-journal collection.

• Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1^c259T cells in Synovial Sarcoma
  D'Angelo SP…Mackall CL Cancer Discovery August 2018.
• CAR-T Cells Surface-Engineered with Drug-Encapsulated Nanoparticles Can Ameliorate Intratumoral T-cell Hypofunction
  Siriwon N…Wang P Cancer Immunology Research July 2018.
• Development of MGD007, a gpA33 x CD3-Bispecific DART Protein for T-Cell Immunotherapy of Metastatic Colorectal Cancer
  Moore PA…Johnson S Molecular Cancer Therapeutics August 2018.
• Enhancing the potency and specificity of engineered T cells for cancer treatment
  Sukumaran S…Vera JF Cancer Discovery August 2018.
• IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma
  Ladomersky E…Wainwright DA Clinical Cancer Research June 2018.
• IL21 Therapy Combined with PD-1 and Tim-3 Blockade Provides Enhanced NK Cell Antitumor Activity against MHC Class I-Deficient Tumors
  Seo H…Kang C Cancer Immunology Research June 2018.
• Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus–Driven Production of a Bispecific T-cell Engager
  Wing A…Guedan S Cancer Immunology Research May 2018.
• Landscape of Tumor Mutation Load, Mismatch Repair Deficiency, and PD-L1 Expression in a Large Patient Cohort of Gastrointestinal Cancers
  Salem ME…Lenz HJ Molcular Cancer Research May 2018.
• Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer
  Quaranta V…Schmid MC Cancer Research August 2018.
• Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy
  Saito R…Kim WY Cancer Research July 2018.
• PD-1 Blockade and CD27 Stimulation Activate Distinct Transcriptional Programs That Synergize for CD8⁺ T-Cell–Driven Antitumor Immunity
  Buchan SL…Al-Shamkhani A Clinical Cancer Research May 2018.
• The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity
  Danilova L…Smith KN Cancer Immunology Research August 2018.
• The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression
  Huang L…Hwu P Clinical Cancer Research July 2018.