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Disparities in Cancer

The number of individuals who survive and thrive after a cancer diagnosis has significantly increased. However, certain populations in the US and globally continue to disproportionately bear the burden of this disease. These disparities result from inequalities in access to cancer screening and care, insufficient tailored resources for specific populations, and variations in cancer biology, environmental exposure, socioeconomic status, and lifestyle. This collection of commentaries, reviews and research articles, spanning the AACR journals, highlights recent advances in the science addressing cancer health disparities among racial and ethnic minorities, sexual and gender minorities, and other medically underserved populations. Jing Peng, PhD, Associate Editor, Cancer Prevention Research and Cancer Epidemiology, Biomarkers & Prevention ([email protected]).

Commentary

AACR Cancer Disparities Progress Report 2024: Achieving the Bold Vision of Health Equity

Patrick A. Williams; Sayyed K. Zaidi; Haleh Ramian; Rajarshi Sengupta

https://doi.org/10.1158/1055-9965.EPI-24-0658

Perspective

Research Silos in Cancer Disparities: Obstacles to Improving Clinical Outcomes for Underserved Patient Populations

Angelique Richardson; Burcu Darst; Genevieve Wojcik; Nikhil Wagle; Svasti Haricharan

https://doi.org/10.1158/1078-0432.CCR-22-3182

In Focus

Challenges and Opportunities in Building a Global Representative Single-Cell and Spatial Atlas in Cancer

Jasmine T. Plummer; Sophia H.L. George

https://doi.org/10.1158/2159-8290.CD-23-0810

ASPO Report

Addressing Social Risks to Accelerate Health Equity in Cancer Prevention and Control

Jean A. McDougall; Theresa A. Hastert; Dede K. Teteh; Charles R. Rogers; Jennifer L. Moss; Carol Y. Ochoa-Dominguez; Perla Chebli; Arnethea L. Sutton; Bo Qin; Erica T. Warner; Serena Xiong

https://doi.org/10.1158/1055-9965.EPI-23-1212

Commentaries

Climate Change and Cancer

Leticia M. Nogueira; Tracy E. Crane; Ana P. Ortiz; Heather D'Angelo; Gila Neta

https://doi.org/10.1158/1055-9965.EPI-22-1234

Review

Structural Racism, Lifestyle Behaviors, and Obesity-related Cancers among Black and Hispanic/Latino Adults in the United States: A Narrative Review

Margaret S. Pichardo; Leah M. Ferrucci; Yamile Molina; Denise A. Esserman; Melinda L. Irwin

https://doi.org/10.1158/1055-9965.EPI-22-1147

Review

PARP-ish: Gaps in Molecular Understanding and Clinical Trials Targeting PARP Exacerbate Racial Disparities in Prostate Cancer

Moriah L. Cunningham; Matthew J. Schiewer

https://doi.org/10.1158/0008-5472.CAN-23-3458

Research Articles
Chronic Health Conditions, Disability, and Physical and Cognitive Limitations among LGBTQ+ Cancer Survivors
Austin R. Waters; Mu Jin; Shaun R. Jones; Geetanjali D. Datta; Eboneé N. Butler; Erin E. Kent; Hazel B. Nichols; Kelly Tan
https://doi.org/10.1158/1055-9965.EPI-24-0166
The Effect of Exposure to Neighborhood Violence on Glucocorticoid Receptor Signaling in Lung Tumors
Hannah Heath; Jin Y. Yoo; Sabrina Akter; Atharva Jain; Vani Sharma; Hannah McGee; Aiman Soliman; Abeer M. Mahmoud; Alicia K. Matthews; Robert A. Winn; Zeynep Madak-Erdogan; Sage J. Kim
https://doi.org/10.1158/2767-9764.CRC-24-0032
Disparities in Access to Liver Transplant Referral and Evaluation among Patients with Hepatocellular Carcinoma in Georgia
Katherine Ross-Driscoll; Arrey-Takor Ayuk-Arrey; Raymond Lynch; Lauren E. McCullough; Giorgio Roccaro; Lauren Nephew; Jonathan Hundley; Raymond A. Rubin; Rachel Patzer
https://doi.org/10.1158/2767-9764.CRC-23-0541
Research Articles
The Association between State-Level Structural Racism and Alcohol and Tobacco Use Behaviors among a National Probability Sample of Black Americans
Nathaniel Woodard; James Butler; Debarchana Ghosh; Kerry M. Green; Cheryl L. Knott
https://doi.org/10.1158/1055-9965.EPI-23-0873
Research Articles
Community-Level Factors Associated with Hepatocellular Carcinoma Incidence and Mortality: An Observational Registry Study
Catherine Mezzacappa; Raiza Rossi; Ariel Jaffe; Tamar H. Taddei; Mario Strazzabosco
https://doi.org/10.1158/1055-9965.EPI-23-0902
Research Articles
Racial Disparities in Accessing Care along the Continuum of Cancer Genetic Service Delivery
Ingrid M. Wagner; Ziming Xuan; Haibo Lu; Catharine Wang
https://doi.org/10.1158/1055-9965.EPI-23-0596
Research Brief
Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications
Britta Weigelt; Antonio Marra; Pier Selenica; Eric Rios-Doria; Amir Momeni-Boroujeni; Michael F. Berger; Kanika Arora; David Nemirovsky; Alexia Iasonos; Debyani Chakravarty; Nadeem R. Abu-Rustum; Arnaud Da Cruz Paula; Kimberly Dessources; Lora H. Ellenson; Ying L. Liu; Carol Aghajanian; Carol L. Brown
https://doi.org/10.1158/2159-8290.CD-23-0546
Review
Updated Review of Major Cancer Risk Factors and Screening Test use in the United States, with a Focus on Changes During the COVID-19 Pandemic
Jessica Star; Priti Bandi; Nigar Nargis; Farhad Islami; K. Robin Yabroff; Adair K. Minihan; Robert A. Smith; Ahmedin Jemal
https://doi.org/10.1158/1055-9965.EPI-23-0114
Research Articles
Recent Mortality Patterns and Time Trends for the Major Cancers in 47 Countries Worldwide
Ephrem Sedeta; Hyuna Sung; Mathieu Laversanne; Freddie Bray; Ahmedin Jemal
https://doi.org/10.1158/1055-9965.EPI-22-1133
Research Articles
Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa
Marcus Bauer; Martina Vetter; Kathrin Stückrath; Meron Yohannes; Zelalem Desalegn; Tewodros Yalew; Yonas Bekuretsion; Tariku W. Kenea; Maureen Joffe; Eunice J. van den Berg; Julien I. Nikulu; Kamate Bakarou; Shyam S. Manraj; Olufemi J. Ogunbiyi; Ima-Obong Ekanem; Festus Igbinoba; Mohenou Diomande; Clement Adebamowo; Charles P. Dzamalala; Angelica A. Anele; Annelle Zietsman; Moses Galukande; Milena Foerster; Isabel dos-Santos-Silva; Biying Liu; Pablo Santos; Ahmedin Jemal; Tamrat Abebe; Claudia Wickenhauser; Barbara Seliger; Valerie McCormack; Eva J. Kantelhardt
https://doi.org/10.1158/2326-6066.CIR-22-0795
Research Articles
Racial, Ethnic, and Sex-based Disparities among High-risk Individuals Undergoing Pancreatic Cancer Surveillance
Bryson W. Katona; Kelsey Klute; Randall E. Brand; Jessica N. Everett; James J. Farrell; Kieran Hawthorne; Vivek Kaul; Sonia S. Kupfer; Salvatore Paiella; Diane M. Simeone; Daniel A. Sussman; George Zogopoulos; Aimee L. Lucas; Fay Kastrinos; the PRECEDE Consortium; Yan Bi; Teresa Brentnall; Daniel Chung; Julie Earl; Srinivas Gaddam; Steve Gallinger; John J. Graff; William Greenhalf; Aaron Grossberg; Philip Hart; Gregory Idos; Joanne Jeter; James Lindberg; Andrew Lowy; Jennifer Permuth; Maria Raitses-Gurevich; Intan Schrader; Jens Siveke; Elena Stoffel; Marlies Vornhuelz; Raymond Wadlow
https://doi.org/10.1158/1940-6207.CAPR-22-0529
Research Articles
Opportunities for Achieving the Cancer Moonshot Goal of a 50% Reduction in Cancer Mortality by 2047
Meredith S. Shiels; Stanley Lipkowitz; Nicole G. Campos; Mark Schiffman; John T. Schiller; Neal D. Freedman; Amy Berrington de González
https://doi.org/10.1158/2159-8290.CD-23-0208
Research Articles
Rural, Large Town, and Urban Differences in Optimal Subspecialty Follow-up and Survivorship Care Plan Documentation among Childhood Cancer Survivors
David H. Noyd; Amanda E. Janitz; Ashley A. Baker; William H. Beasley; Nancy C. Etzold; David C. Kendrick; Kevin C. Oeffinger
https://doi.org/10.1158/1055-9965.EPI-22-0966
Research Articles
Determinants of Lung Cancer Screening in a Minnesota Urban Indigenous Community: A Community-Based, Participatory, Action-Oriented Study
Madison D. Anderson; Wyatt J. Pickner; Abbie Begnaud
https://doi.org/10.1158/1940-6207.CAPR-22-0314

AACR Journals

 

 

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