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AI and Data Science
Rapid developments of methods using artificial intelligence (AI), deep learning and data science have enabled major discoveries in cancer research in recent years. This collection presents studies, published in the AACR journals, using these methods to develop technologies for clinical data analyses, prediction of drug responses, analyses of immune responses and the tumor microenvironment and imaging. The collection demonstrates the breadth of advances using these tools and highlights the potential benefits of their applications for cancer patients. Avital (Tali) Lev, PhD, Senior Editor, Cancer Discovery ([email protected]).
In Focus
Irene Dankwa-Mullan; Dilhan Weeraratne
Doi: 10.1158/2159-8290.CD-22-0373
Review
Narmin Ghaffari Laleh; Marta Ligero; Raquel Perez-Lopez; Jakob Nikolas Kather
Doi: 10.1158/1078-0432.CCR-22-0390
Perspective
Jacob Rosenthal; Ryan Carelli; Mohamed Omar; David Brundage; Ella Halbert; Jackson Nyman; Surya N. Hari; Eliezer M. Van Allen; Luigi Marchionni; Renato Umeton; Massimo Loda
Doi: 10.1158/1541-7786.MCR-21-0665
Resource Report
Bodong Liu; Yanting Zhu; Zhenye Yang; Helen H.N. Yan; Suet Yi Leung; Jue Shi
Resource Report
Ino de Bruijn; Ritika Kundra; Brooke Mastrogiacomo; Thinh Ngoc Tran; Luke Sikina; Tali Mazor; Xiang Li; Angelica Ochoa; Gaofei Zhao; Bryan Lai; Adam Abeshouse; Diana Baiceanu; Ersin Ciftci; Ugur Dogrusoz; Andrew Dufilie; Ziya Erkoc; Elena Garcia Lara; Zhaoyuan Fu; Benjamin Gross; Charles Haynes; Allison Heath; David Higgins; Prasanna Jagannathan; Karthik Kalletla; Priti Kumari; James Lindsay; Aaron Lisman; Bas Leenknegt; Pieter Lukasse; Divya Madela; Ramyasree Madupuri; Pim van Nierop; Oleguer Plantalech; Joyce Quach; Adam C. Resnick; Sander Y.A. Rodenburg; Baby A. Satravada; Fedde Schaeffer; Robert Sheridan; Jessica Singh; Rajat Sirohi; Selcuk Onur Sumer; Sjoerd van Hagen; Avery Wang; Manda Wilson; Hongxin Zhang; Kelsey Zhu; Nicole Rusk; Samantha Brown; Jessica A. Lavery; Katherine S. Panageas; Julia E. Rudolph; Michele L. LeNoue-Newton; Jeremy L. Warner; Xindi Guo; Haley Hunter-Zinck; Thomas V. Yu; Shirin Pilai; Chelsea Nichols; Stuart M. Gardos; John Philip; AACR Project GENIE BPC Core Team, AACR Project GENIE Consortium; Kenneth L. Kehl; Gregory J. Riely; Deborah Schrag; Jocelyn Lee; Michael V. Fiandalo; Shawn M. Sweeney; Trevor J. Pugh; Chris Sander; Ethan Cerami; Jianjiong Gao; Nikolaus Schultz
Matthew Davis; Kit Simpson; Leslie A. Lenert; Vanessa Diaz; Alexander V. Alekseyenko
Kianoush Falahkheirkhah; Sudipta S. Mukherjee; Sounak Gupta; Loren Herrera-Hernandez; Michael R. McCarthy; Rafael E. Jimenez; John C. Cheville; Rohit Bhargava
Michal Kazmierski; Mattea Welch; Sejin Kim; Chris McIntosh; Katrina Rey-McIntyre; Shao Hui Huang; Tirth Patel; Tony Tadic; Michael Milosevic; Fei-Fei Liu; Adam Ryczkowski; Joanna Kazmierska; Zezhong Ye; Deborah Plana; Hugo J.W.L. Aerts; Benjamin H. Kann; Scott V. Bratman; Andrew J. Hope; Benjamin Haibe-Kains
Research Articles
Georges Bedran; Hans-Christof Gasser; Kenneth Weke; Tongjie Wang; Dominika Bedran; Alexander Laird; Christophe Battail; Fabio Massimo Zanzotto; Catia Pesquita; Håkan Axelson; Ajitha Rajan; David J. Harrison; Aleksander Palkowski; Maciej Pawlik; Maciej Parys; J. Robert O'Neill; Paul M. Brennan; Stefan N. Symeonides; David R. Goodlett; Kevin Litchfield; Robin Fahraeus; Ted R. Hupp; Sachin Kote; Javier A. Alfaro
Research Articles
Zachariah H. Foda; Akshaya V. Annapragada; Kavya Boyapati; Daniel C. Bruhm; Nicholas A. Vulpescu; Jamie E. Medina; Dimitrios Mathios; Stephen Cristiano; Noushin Niknafs; Harry T. Luu; Michael G. Goggins; Robert A. Anders; Jing Sun; Shruti H. Meta; David L. Thomas; Gregory D. Kirk; Vilmos Adleff; Jillian Phallen; Robert B. Scharpf; Amy K. Kim; Victor E. Velculescu
Research Briefs
Tim Heinemann; Christoph Kornauth; Yannik Severin; Gregory I. Vladimer; Tea Pemovska; Emir Hadzijusufovic; Hermine Agis; Maria-Theresa Krauth; Wolfgang R. Sperr; Peter Valent; Ulrich Jäger; Ingrid Simonitsch-Klupp; Giulio Superti-Furga; Philipp B. Staber; Berend Snijder
Convergence and Technologies
Chengyue Wu; Angela M. Jarrett; Zijian Zhou; Nabil Elshafeey; Beatriz E. Adrada; Rosalind P. Candelaria; Rania M.M. Mohamed; Medine Boge; Lei Huo; Jason B. White; Debu Tripathy; Vicente Valero; Jennifer K. Litton; Clinton Yam; Jong Bum Son; Jingfei Ma; Gaiane M. Rauch; Thomas E. Yankeelov
Research Articles
Trevor J. Pugh; Jonathan L. Bell; Jeff P. Bruce; Gary J. Doherty; Matthew Galvin; Michelle F. Green; Haley Hunter-Zinck; Priti Kumari; Michele L. Lenoue-Newton; Marilyn M. Li; James Lindsay; Tali Mazor; Andrea Ovalle; Stephen-John Sammut; Nikolaus Schultz; Thomas V. Yu; Shawn M. Sweeney; Brady Bernard; for the AACR Project GENIE Consortium, Genomics and Analysis Working Group
Research Articles
The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution
Ajit J. Nirmal; Zoltan Maliga; Tuulia Vallius; Brian Quattrochi; Alyce A. Chen; Connor A. Jacobson; Roxanne J. Pelletier; Clarence Yapp; Raquel Arias-Camison; Yu-An Chen; Christine G. Lian; George F. Murphy; Sandro Santagata; Peter K. Sorger
Targeting Drug Resistance
Elizabeth A. Coker; Adam Stewart; Bugra Ozer; Anna Minchom; Lisa Pickard; Ruth Ruddle; Suzanne Carreira; Sanjay Popat; Mary O'Brien; Florence Raynaud; Johann de Bono; Bissan Al-Lazikani; Udai Banerji
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