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Advances in Tumor Immunology and Immunotherapy

Cancer immunotherapies are rapidly evolving to render better health outcomes for cancer patients. This collection of research and review articles from the AACR journals highlights recent advances in cancer immunology, and explores promising pathways with therapeutic potential. Improvements in neoantigen discovery, CAR T cell therapy, checkpoint inhibitor identification, as well as a better understanding of how the microbiome affects cancer outcomes all contribute to a comprehensive exploration of the current state of tumor immunology. Further, this collection includes studies on how innate and adaptive immune cells, and cells within the tumor microenvironment such as stromal cells, are altered and can be targeted for improved cancer immunotherapies. Alia Sajani, PhD, Assistant Editor, Cancer Immunology Research ([email protected])


In Focus

Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges

Nicholas J. Haradhvala; Marcela V. Maus

https://doi.org/10.1158/2643-3230.bcd-23-0212

Rising Stars in Cancer Immunology

CD4+ Regulatory T Cells in Human Cancer: Subsets, Origin, and Molecular Regulation

Julian Swatler; Marco De Luca; Ivano Rotella; Veronica Lise; Emilia Maria Cristina Mazza; Enrico Lugli

https://doi.org/10.1158/2326-6066.cir-23-0517

Special Collection Image
Hao-Wei Teng; Tean-Ya Wang; Chun-Chi Lin; Zhen-Jie Tong; Hsiao-Wei Cheng; Hsiang-Tsui Wang
Isabella C. Glitza; Yongwoo David Seo; Christine N. Spencer; Jennifer R. Wortman; Elizabeth M. Burton; Farah A. Alayli; Christopher P. Loo; Shikha Gautam; Ashish Damania; Julie Densmore; Justin Fairchild; Christopher R. Cabanski; Matthew C. Wong; Christine B. Peterson; Brian Weiner; Nathan Hicks; John Aunins; Christopher McChalicher; Emily Walsh; Michael T. Tetzlaff; Omid Hamid; Patrick A. Ott; Genevieve M. Boland; Ryan J. Sullivan; Kenneth F. Grossmann; Nadim J. Ajami; Theresa LaVallee; Matthew R. Henn; Hussein A. Tawbi; Jennifer A. Wargo
Junghyun Lim; Ryan Rodriguez; Katherine Williams; John Silva; Alan G. Gutierrez; Paul Tyler; Faezzah Baharom; Tao Sun; Eva Lin; Scott Martin; Brandon D. Kayser; Robert J. Johnston; Ira Mellman; Lélia Delamarre; Nathaniel R. West; Sören Müller; Yan Qu; Klaus Heger
Michael V. Martin; Salvador Aguilar-Rosas; Katka Franke; Mark Pieterse; Jamie van Langelaar; Renée Schreurs; Maarten F. Bijlsma; Marc G. Besselink; Jan Koster; Wim Timens; Mustafa Khasraw; David M. Ashley; Stephen T. Keir; Christian H. Ottensmeier; Emma V. King; Joanne Verheij; Cynthia Waasdorp; Peter J.M. Valk; Sem A.G. Engels; Ellen Oostenbach; Jip T. van Dinter; Damon A. Hofman; Juk Yee Mok; Wim J.E. van Esch; Hanneke Wilmink; Kim Monkhorst; Henk M.W. Verheul; Dennis Poel; T. Jeroen N. Hiltermann; Léon C.L.T. van Kempen; Harry J.M. Groen; Joachim G.J.V. Aerts; Sebastiaan van Heesch; Bob Löwenberg; Ronald Plasterk; Wigard P. Kloosterman
Handan Xiang; Yidan Pan; Marc A. Sze; Marta Wlodarska; Ling Li; Karyn Ann van de Mark; Haleema Qamar; Casey J. Moure; Douglas E. Linn; Josephine Hai; Ying Huo; James Clarke; Tze Guan Tan; Samantha Ho; Karen W. Teng; Muhammad N. Ramli; Michael Nebozhyn; Chunsheng Zhang; Julianne Barlow; Corinne E. Gustafson; Savanna Gornisiewicz; Thomas P. Albertson; Stephanie L. Korle; Raphael Bueno; Lily Y. Moy; Elisabeth H. Vollmann; Derek Y. Chiang; Philip E. Brandish; Andrey Loboda
Moh'd M. Khushman; Michael D. Toboni; Joanne Xiu; Upender Manne; Alex Farrell; Emil Lou; Anthony F. Shields; Philip A. Philip; Mohamed E. Salem; Jim Abraham; David Spetzler; John Marshall; Priya Jayachandran; Michael J. Hall; Heinz-Josef Lenz; Ibrahim Halil Sahin; Andreas Seeber; Mathew A. Powell
Elizabeth C. Wescott; Xiaopeng Sun; Paula Gonzalez-Ericsson; Ann Hanna; Brandie C. Taylor; Violeta Sanchez; Juliana Bronzini; Susan R. Opalenik; Melinda E. Sanders; Julia Wulfkuhle; Rosa I. Gallagher; Henry Gomez; Claudine Isaacs; Vijaya Bharti; John T. Wilson; Tarah J. Ballinger; Cesar A. Santa-Maria; Payal D. Shah; Elizabeth C. Dees; Brian D. Lehmann; Vandana G. Abramson; Gillian L. Hirst; Lamorna Brown Swigart; Laura J. van ˈt Veer; Laura J. Esserman; Emanuel F. Petricoin; Jennifer A. Pietenpol; Justin M. Balko
Rawan G. Faramand; Sae Bom Lee; Michael D. Jain; Biwei Cao; Xuefeng Wang; Kai Rejeski; Marion Subklewe; Johannes F. Fahrmann; Neeraj Y. Saini; Samir M. Hanash; Yun Pyo Kang; Darwin Chang; Paolo C. Rodriguez; Erin A. Dean; Taiga Nishihori; Bijal D. Shah; Aleksandr Lazaryan; Julio Chavez; Farhad Khimani; Javier A. Pinilla-Ibarz; Marian Dam; Kayla M. Reid; Salvatore A. Corallo; Meghan Menges; Melanie Hidalgo Vargas; Jay K. Mandula; Brian A. Holliday; Christina A. Bachmeier; Kelly Speth; Qinghua Song; Mike Mattie; Frederick L. Locke; Marco L. Davila
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