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Yuzhuo Wang
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Journal Articles

Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer

Amilcar Flores-Morales, Tobias B. Bergmann, Charlotte Lavallee, Tanveer S. Batth, Dong Lin, Mads Lerdrup, Stine Friis, Anette Bartels, Gitte Kristensen, Agnieszka Krzyzanowska, Hui Xue, Ladan Fazli, Klaus H. Hansen, Martin A. Røder, Klaus Brasso, José M. Moreira, Anders Bjartell, Yuzhuo Wang, Jesper V. Olsen, Colin C. Collins, Diego Iglesias-Gato
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (2): 595–608.
https://doi.org/10.1158/1078-0432.CCR-18-0729
Published: 15 January 2019
View article titled, Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

BIRC6 Targeting as Potential Therapy for Advanced, Enzalutamide-Resistant Prostate Cancer

Iris Sze Ue Luk, Raunak Shrestha, Hui Xue, Yuwei Wang, Fang Zhang, Dong Lin, Anne Haegert, Rebecca Wu, Xin Dong, Colin C. Collins, Amina Zoubeidi, Martin E. Gleave, Peter W. Gout, Yuzhuo Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (6): 1542–1551.
https://doi.org/10.1158/1078-0432.CCR-16-0718
Published: 14 March 2017
View article titled, <em>BIRC6</em> Targeting as Potential Therapy for Advanced, Enzalutamide-Resistant Prostate Cancer
Open the PDF for <em>BIRC6</em> Targeting as Potential Therapy for Advanced, Enzalutamide-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

The MCT4 Gene: A Novel, Potential Target for Therapy of Advanced Prostate Cancer

Stephen Yiu Chuen Choi, Hui Xue, Rebecca Wu, Ladan Fazli, Dong Lin, Colin C. Collins, Martin E. Gleave, Peter W. Gout, Yuzhuo Wang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (11): 2721–2733.
https://doi.org/10.1158/1078-0432.CCR-15-1624
Published: 31 May 2016
View article titled, The <em>MCT4</em> Gene: A Novel, Potential Target for Therapy of Advanced Prostate Cancer
Open the PDF for The <em>MCT4</em> Gene: A Novel, Potential Target for Therapy of Advanced Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer

Arun A. Azad, Stanislav V. Volik, Alexander W. Wyatt, Anne Haegert, Stephane Le Bihan, Robert H. Bell, Shawn A. Anderson, Brian McConeghy, Robert Shukin, Jenny Bazov, Jack Youngren, Pamela Paris, George Thomas, Eric J. Small, Yuzhuo Wang, Martin E. Gleave, Colin C. Collins, Kim N. Chi
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (10): 2315–2324.
https://doi.org/10.1158/1078-0432.CCR-14-2666
Published: 14 May 2015
View article titled, Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer
Open the PDF for Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Generation 2.5 Antisense Oligonucleotides Targeting the Androgen Receptor and Its Splice Variants Suppress Enzalutamide-Resistant Prostate Cancer Cell Growth

Yoshiaki Yamamoto, Yohann Loriot, Eliana Beraldi, Fan Zhang, Alexander W. Wyatt, Nader Al Nakouzi, Fan Mo, Tianyuan Zhou, Youngsoo Kim, Brett P. Monia, A. Robert MacLeod, Ladan Fazli, Yuzhuo Wang, Colin C. Collins, Amina Zoubeidi, Martin Gleave
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (7): 1675–1687.
https://doi.org/10.1158/1078-0432.CCR-14-1108
Published: 31 March 2015
View article titled, Generation 2.5 Antisense Oligonucleotides Targeting the Androgen Receptor and Its Splice Variants Suppress Enzalutamide-Resistant Prostate Cancer Cell Growth
Open the PDF for Generation 2.5 Antisense Oligonucleotides Targeting the Androgen Receptor and Its Splice Variants Suppress Enzalutamide-Resistant Prostate Cancer Cell Growth in another window
Includes: Supplementary data
Journal Articles

Tumor Growth Inhibition by Olaparib in BRCA2 Germline-Mutated Patient-Derived Ovarian Cancer Tissue Xenografts

Ursula Kortmann, Jessica N. McAlpine, Hui Xue, Jun Guan, Gavin Ha, Sophie Tully, Sharaz Shafait, Alan Lau, Aaron N. Cranston, Mark J. O'Connor, David G. Huntsman, Yuzhuo Wang, C. Blake Gilks
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 783–791.
https://doi.org/10.1158/1078-0432.CCR-10-1382
Published: 15 February 2011
View article titled, Tumor Growth Inhibition by Olaparib in <em>BRCA2</em> Germline-Mutated Patient-Derived Ovarian Cancer Tissue Xenografts
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Includes: Supplementary data
Journal Articles

Patient-Derived First Generation Xenografts of Non–Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy

Xin Dong, Jun Guan, John C. English, Julia Flint, John Yee, Kenneth Evans, Nevin Murray, Calum MacAulay, Raymond T. Ng, Peter W. Gout, Wan L. Lam, Janessa Laskin, Victor Ling, Stephen Lam, Yuzhuo Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1442–1451.
https://doi.org/10.1158/1078-0432.CCR-09-2878
Published: 28 February 2010
View article titled, Patient-Derived First Generation Xenografts of Non–Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy
Open the PDF for Patient-Derived First Generation Xenografts of Non–Small Cell Lung Cancers: Promising Tools for Predicting Drug Responses for Personalized Chemotherapy in another window