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Journal Articles

Homoharringtonine Added to Venetoclax and Azacitidine Improves Outcome and Mitigates Genetic Impact in Relapsed/Refractory AML: A Multicenter Cohort Study

Guopan Yu, Yu Zhang, Sijian Yu, Zhao Yin, Guangyang Weng, Na Xu, Xin Du, Dongjun Lin, Jie Xiao, Zhiqiang Sun, Hongyu Zhang, Xinquan Liang, Ziwen Guo, Weihua Zhao, Min Dai, Zhiping Fan, Li Xuan, Hui Liu, Dan Xu, Jieyu Ye, Xuejie Jiang, Pengcheng Shi, Hua Jin, Qifa Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (1): 87–97.
https://doi.org/10.1158/1078-0432.CCR-24-1332
Published: 06 January 2025
View article titled, Homoharringtonine Added to Venetoclax and Azacitidine Improves Outcome and Mitigates Genetic Impact in Relapsed/Refractory AML: A Multicenter Cohort Study
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Includes: Supplementary data
Journal Articles

Personalized MRD Assessment in Perisurgical ctDNA for Prognostic Prediction in Hepatocellular Carcinoma

Jie Hu, Haoran Tang, Can-Can Jia, Xiang-Yu Zhang, Ying Xu, Jin-Peng Tan, Jia Fan, Shidong Jia, Jian Zhou
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF10.
https://doi.org/10.1158/1078-0432.CCR-24-1897
Published: 05 December 2024
View article titled, Personalized MRD Assessment in Perisurgical ctDNA for Prognostic Prediction in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Comprehensive DNA Methylation Profiling of Medullary Thyroid Carcinoma: Molecular Classification, Potential Therapeutic Target, and Classifier System

Cenkai Shen, Xiao Shi, Duo Wen, Yuqing Zhang, Yuxin Du, Yu Zhang, Ben Ma, Haitao Tang, Min Yin, Naisi Huang, Tian Liao, Ting-Ting Zhang, Chang’e Kong, Wenjun Wei, Qinghai Ji, Yu Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (1): 127–138.
https://doi.org/10.1158/1078-0432.CCR-23-2142
Published: 05 January 2024
View article titled, Comprehensive DNA Methylation Profiling of Medullary Thyroid Carcinoma: Molecular Classification, Potential Therapeutic Target, and Classifier System
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Includes: Supplementary data
Journal Articles

Safety and Tolerability of Low-Dose Radiation and Stereotactic Body Radiotherapy + Sintilimab for Treatment-Naïve Stage IV PD-L1+ Non–Small Cell Lung Cancer Patients

Xiaojuan Zhou, Laiyan Zhou, Zhuoran Yao, Meijuan Huang, Youling Gong, Bingwen Zou, Jiang Zhu, Yongmei Liu, Feng Peng, Yan Zhang, Min Yu, Yanying Li, Feifei Na, Yijun Wu, Kai Kang, Weigang Xiu, Xuanwei Zhang, Lin Zhou, Yong Xu, Jin Wang, Yan Wang, Xue Yang, Yuanjun Wu, Rui Li, Yu Zhang, Zhenzhou Yang, Zhipeng Zhou, Jing Bai, Xin Yi, Ruizhan Tong, Limei Yin, Chong Chen, Gabriele Niedermann, You Lu, Jianxin Xue
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (20): 4098–4108.
https://doi.org/10.1158/1078-0432.CCR-23-0315
Published: 13 October 2023
View article titled, Safety and Tolerability of Low-Dose Radiation and Stereotactic Body Radiotherapy + Sintilimab for Treatment-Naïve Stage IV PD-L1<sup>+</sup> Non–Small Cell Lung Cancer Patients
Open the PDF for Safety and Tolerability of Low-Dose Radiation and Stereotactic Body Radiotherapy + Sintilimab for Treatment-Naïve Stage IV PD-L1<sup>+</sup> Non–Small Cell Lung Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Correction: Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR–mediated DNA Damage Response

Li Ding, Vijay S. Madamsetty, Spencer Kiers, Olga Alekhina, Andrey Ugolkov, John Dube, Yu Zhang, Jin-San Zhang, Enfeng Wang, Shamit K. Dutta, Daniel M. Schmitt, Francis J. Giles, Alan P. Kozikowski, Andrew P. Mazar, Debabrata Mukhopadhyay, Daniel D. Billadeau
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 4128.
https://doi.org/10.1158/1078-0432.CCR-21-2114
Published: 15 July 2021
View article titled, Correction: Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR–mediated DNA Damage Response
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Journal Articles

An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy

Yun Wang, Yan-yu Cai, Tobias Herold, Run-cong Nie, Yu Zhang, Robert Peter Gale, Klaus H. Metzeler, Yun Zeng, Shun-qing Wang, Xue-yi Pan, Tong-hua Yang, Yuan-bin Wu, Qing Zhang, Zhi-jun Wuxiao, Xin Du, Zhi-wei Liang, Yong-zhong Su, Jing-bo Xu, Yong-qing Wang, Ze-lin Liu, Jian-wei Wu, Xiong Zhang, Bing-yi Wu, Ruo-zhi Xiao, San-bin Wang, Jin-yuan Li, Pei-dong Chi, Qian-yi Zhang, Si-liang Chen, Zhe-yuan Qin, Xin-mei Zhang, Na Zhong, Wolfgang Hiddemann, Qi-fa Liu, Bei Zhang, Yang Liang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 255–266.
https://doi.org/10.1158/1078-0432.CCR-20-3417
Published: 04 January 2021
View article titled, An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy
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Includes: Supplementary data
Journal Articles

DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN–WEE1 Signaling

Jie Li, Chaoyun Pan, Austin C. Boese, JiHoon Kang, Anna D. Umano, Kelly R. Magliocca, Wenqing Yang, Yu Zhang, Sagar Lonial, Lingtao Jin, Sumin Kang
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3843–3855.
https://doi.org/10.1158/1078-0432.CCR-19-3790
Published: 15 July 2020
View article titled, DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN–WEE1 Signaling
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Includes: Supplementary data
Journal Articles

Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response

Li Ding, Vijay S. Madamsetty, Spencer Kiers, Olga Alekhina, Andrey Ugolkov, John Dube, Yu Zhang, Jin-San Zhang, Enfeng Wang, Shamit K. Dutta, Daniel M. Schmitt, Francis J. Giles, Alan P. Kozikowski, Andrew P. Mazar, Debabrata Mukhopadhyay, Daniel D. Billadeau
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (21): 6452–6462.
https://doi.org/10.1158/1078-0432.CCR-19-0799
Published: 01 November 2019
View article titled, Glycogen Synthase Kinase-3 Inhibition Sensitizes Pancreatic Cancer Cells to Chemotherapy by Abrogating the TopBP1/ATR-Mediated DNA Damage Response
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Includes: Supplementary data
Journal Articles

The Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells In Vitro and In Vivo

Yu Zhang, Liang Zhou, Dipankar Bandyopadhyay, Kanika Sharma, Alexander Joseph Allen, Maciej Kmieciak, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (20): 6195–6205.
https://doi.org/10.1158/1078-0432.CCR-18-3788
Published: 15 October 2019
View article titled, The Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells <em>In Vitro</em> and <em>In Vivo</em>
Open the PDF for The Covalent CDK7 Inhibitor THZ1 Potently Induces Apoptosis in Multiple Myeloma Cells <em>In Vitro</em> and <em>In Vivo</em> in another window
Includes: Supplementary data
Journal Articles

Abstract B15: Targeting SQSTM1/p62 induces cargo-loading failure and converts autophagy to apoptosis via NBK/Bik in human multiple myeloma cells.

Yun Dai, Shuang Chen, Liang Zhou, Yu Zhang, Yun Leng, Xin-Yan Pei, Hui Lin, Richard Jones, Orlowski Robert, Steven Grant
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): B15.
https://doi.org/10.1158/1557-3265.HEMMAL14-B15
Published: 19 August 2015
View article titled, Abstract B15: Targeting SQSTM1/p62 induces cargo-loading failure and converts autophagy to apoptosis via NBK/Bik in human multiple myeloma cells.
Journal Articles

Calreticulin Promotes Migration and Invasion of Esophageal Cancer Cells by Upregulating Neuropilin-1 Expression via STAT5A

Feng Shi, Li Shang, Bei-Qing Pan, Xiao-Min Wang, Yan-Yi Jiang, Jia-Jie Hao, Yu Zhang, Yan Cai, Xin Xu, Qi-Min Zhan, Ming-Rong Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (23): 6153–6162.
https://doi.org/10.1158/1078-0432.CCR-14-0583
Published: 30 November 2014
View article titled, Calreticulin Promotes Migration and Invasion of Esophageal Cancer Cells by Upregulating Neuropilin-1 Expression via STAT5A
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Includes: Supplementary data
Journal Articles

CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer

Yong-Jian Deng, Na Tang, Chao Liu, Jiang-Yu Zhang, Sheng-Li An, Yin-Li Peng, Li-Li Ma, Guang-Qiu Li, Qiang Jiang, Chun-Ting Hu, Ya-Nan Wang, Yao-Ze Liang, Xiu-Wu Bian, Wei-Gang Fang, Yan-Qing Ding
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (14): 3809–3817.
https://doi.org/10.1158/1078-0432.CCR-13-1887
Published: 14 July 2014
View article titled, CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer
Open the PDF for CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma

Dong Ni, Xin Ma, Hong-Zhao Li, Yu Gao, Xin-Tao Li, Yu Zhang, Qing Ai, Peng Zhang, Er-Lin Song, Qing-Bo Huang, Yang Fan, Xu Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (7): 1779–1790.
https://doi.org/10.1158/1078-0432.CCR-13-1687
Published: 31 March 2014
View article titled, Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma
Open the PDF for Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization

Zhi-Zhou Shi, Li Shang, Yan-Yi Jiang, Jia-Jie Hao, Yu Zhang, Tong-Tong Zhang, De-Chen Lin, Shu-Guang Liu, Bo-Shi Wang, Ting Gong, Qi-Min Zhan, Ming-Rong Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5867–5878.
https://doi.org/10.1158/1078-0432.CCR-12-3753
Published: 31 October 2013
View article titled, Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Open the PDF for Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization in another window
Includes: Supplementary data
Journal Articles

The Tumor-Suppressive Function of UNC5D and Its Repressed Expression in Renal Cell Carcinoma

Dan Lu, Dong Dong, Yu Zhou, Min Lu, Xue-Wen Pang, Yan Li, Xiao-Jun Tian, Yu Zhang, Jun Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (11): 2883–2892.
https://doi.org/10.1158/1078-0432.CCR-12-2978
Published: 30 May 2013
View article titled, The Tumor-Suppressive Function of <em>UNC5D</em> and Its Repressed Expression in Renal Cell Carcinoma
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Includes: Supplementary data
Journal Articles

PLK1 Is Transcriptionally Activated by NF-κB during Cell Detachment and Enhances Anoikis Resistance through Inhibiting β-Catenin Degradation in Esophageal Squamous Cell Carcinoma

De-Chen Lin, Yu Zhang, Qin-Jing Pan, Hai Yang, Zhi-Zhou Shi, Zhi-Hui Xie, Bo-Shi Wang, Jia-Jie Hao, Tong-Tong Zhang, Xin Xu, Qi-Min Zhan, Ming-Rong Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4285–4295.
https://doi.org/10.1158/1078-0432.CCR-10-3236
Published: 05 July 2011
View article titled, PLK1 Is Transcriptionally Activated by NF-κB during Cell Detachment and Enhances Anoikis Resistance through Inhibiting β-Catenin Degradation in Esophageal Squamous Cell Carcinoma
Open the PDF for PLK1 Is Transcriptionally Activated by NF-κB during Cell Detachment and Enhances Anoikis Resistance through Inhibiting β-Catenin Degradation in Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Isolation of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma Using a Novel Cell Separation Strategy

Wen Xu, Lu Cao, Lei Chen, Jing Li, Xiao-Feng Zhang, Hai-Hua Qian, Xiao-Yan Kang, Yu Zhang, Jian Liao, Le-Hua Shi, Ye-Fa Yang, Meng-Chao Wu, Zheng-Feng Yin
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (11): 3783–3793.
https://doi.org/10.1158/1078-0432.CCR-10-0498
Published: 01 June 2011
View article titled, Isolation of Circulating Tumor Cells in Patients with Hepatocellular Carcinoma Using a Novel Cell Separation Strategy
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Journal Articles

Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma

Xiao-Song Wang, Zheng Zhang, Hong-Cheng Wang, Jian-Liang Cai, Qing-Wen Xu, Meng-Qiang Li, Yi-Cheng Chen, Xiao-Ping Qian, Tian-Jing Lu, Li-Zhang Yu, Yu Zhang, Dian-Qi Xin, Yan-Qun Na, Wei-Feng Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (16): 4851–4858.
https://doi.org/10.1158/1078-0432.CCR-06-0134
Published: 16 August 2006
View article titled, Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma
Open the PDF for Rapid Identification of UCA1 as a Very Sensitive and Specific Unique Marker for Human Bladder Carcinoma in another window
Includes: Supplementary data