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Journal Articles

A Grant-Based Experiment to Train Clinical Investigators: The AACR/ASCO Methods in Clinical Cancer Research Workshop

Daniel D. Von Hoff, Gary M. Clark, Charles A. Coltman, Mary L. Disis, S.G. Eckhardt, Lee M. Ellis, Margaret Foti, Elizabeth Garrett-Mayer, Mithat Gönen, Manuel Hidalgo, Susan G. Hilsenbeck, John H. Littlefield, Patricia M. LoRusso, H. Kim Lyerly, Neal J. Meropol, Jyoti D. Patel, Steven Piantadosi, Dean A. Post, Meredith M. Regan, Yu Shyr, Margaret A. Tempero, Joel E. Tepper, Jamie Von Roenn, Louis M. Weiner, Donn C. Young, Nu V. Vu
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (20): 5472–5481.
DOI: https://doi.org/10.1158/1078-0432.CCR-21-1799
Published: 15 October 2021
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Abstract S01-02: Assessing vulnerability of patients with lung cancer to SARS-CoV-2 infection based on serological antibody analyses

Amy C. Moore, Paul A Bunn, Jr., Beatriz Fontoura, Adolfo García-Sastre, Jorge Gomez, Florian Krammer, Phillip Mack, John D. Minna, Christian Rolfo, Yu Shyr, Peter Ujhazy, Fred R. Hirsch
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6_Supplement): S01-02.
DOI: https://doi.org/10.1158/1557-3265.COVID-19-21-S01-02
Published: 15 March 2021
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Abstract S12-03: Thoracic cancers international COVID-19 collaboration (TERAVOLT): Small-cell lung cancer and other rare thoracic malignancies

Alessio Cortellini, Anne-Marie C. Dingemans, Oscar Arrieta, Javier Baena, Matteo Brighenti, Enriqueta Felip, Marina Chiara Garassino, Pilar Garrido, Carlo Genova, Federica Grosso, Leora Horn, Li-Ching Huang, Jan Van Meerbeeck, Solange Peters, Ernest Nadal, Jacobo Rogado, Yu Shyr, Marcello Tiseo, Valter Torri, Annalisa Trama, Heather Wakelee, Jennifer G Whisenant, Giuseppe Viscardi, Fabrice Barlesi, Sanjay Popat
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18_Supplement): S12-03.
DOI: https://doi.org/10.1158/1557-3265.COVID-19-S12-03
Published: 15 September 2020
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Journal Articles

TBCRC 032 IB/II Multicenter Study: Molecular Insights to AR Antagonist and PI3K Inhibitor Efficacy in Patients with AR+ Metastatic Triple-Negative Breast Cancer

Brian D. Lehmann, Vandana G. Abramson, Melinda E. Sanders, Erica L. Mayer, Tufia C. Haddad, Rita Nanda, Catherine Van Poznak, Anna Maria Storniolo, Julie R. Nangia, Paula I. Gonzalez-Ericsson, Violeta Sanchez, Kimberly N. Johnson, Richard G. Abramson, Sheau-Chiann Chen, Yu Shyr, Carlos L. Arteaga, Antonio C. Wolff, Jennifer A. Pietenpol
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (9): 2111–2123.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-2170
Published: 01 May 2020
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The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2)

Dara L. Aisner, Lynette M. Sholl, Lynne D. Berry, Michael R. Rossi, Heidi Chen, Junya Fujimoto, Andre L. Moreira, Suresh S. Ramalingam, Liza C. Villaruz, Gregory A. Otterson, Eric Haura, Katerina Politi, Bonnie Glisson, Jeremy Cetnar, Edward B. Garon, Joan Schiller, Saiama N. Waqar, Lecia V. Sequist, Julie Brahmer, Yu Shyr, Kelly Kugler, Ignacio I. Wistuba, Bruce E. Johnson, John D. Minna, Mark G. Kris, Paul A. Bunn, David J. Kwiatkowski
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (5): 1038–1047.
DOI: https://doi.org/10.1158/1078-0432.CCR-17-2289
Published: 28 February 2018
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A Randomized Phase II Neoadjuvant Study of Cisplatin, Paclitaxel With or Without Everolimus in Patients with Stage II/III Triple-Negative Breast Cancer (TNBC): Responses and Long-term Outcome Correlated with Increased Frequency of DNA Damage Response Gene Mutations, TNBC Subtype, AR Status, and Ki67

Bojana Jovanović, Ingrid A. Mayer, Erica L. Mayer, Vandana G. Abramson, Aditya Bardia, Melinda E. Sanders, M. Gabriela Kuba, Monica V. Estrada, J. Scott Beeler, Timothy M. Shaver, Kimberly C. Johnson, Violeta Sanchez, Jennifer M. Rosenbluth, Patrick M. Dillon, Andres Forero-Torres, Jenny C. Chang, Ingrid M. Meszoely, Ana M. Grau, Brian D. Lehmann, Yu Shyr, Quanhu Sheng, Sheau-Chiann Chen, Carlos L. Arteaga, Jennifer A. Pietenpol
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (15): 4035–4045.
DOI: https://doi.org/10.1158/1078-0432.CCR-16-3055
Published: 01 August 2017
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Contribution of Beta-HPV Infection and UV Damage to Rapid-Onset Cutaneous Squamous Cell Carcinoma during BRAF-Inhibition Therapy

Daniel N. Cohen, Steven K. Lawson, Aaron C. Shaver, Liping Du, Harrison P. Nguyen, Qin He, Douglas B. Johnson, Wilfred A. Lumbang, Brent R. Moody, James L. Prescott, Pranil K. Chandra, Alan S. Boyd, Jeffrey P. Zwerner, Jason B. Robbins, Stephen K. Tyring, Peter L. Rady, James D. Chappell, Yu Shyr, Jeffrey R. Infante, Jeffrey A. Sosman
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (11): 2624–2634.
DOI: https://doi.org/10.1158/1078-0432.CCR-14-2667
Published: 31 May 2015
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RAF265 Inhibits the Growth of Advanced Human Melanoma Tumors

Yingjun Su, Anna E. Vilgelm, Mark C. Kelley, Oriana E. Hawkins, Yan Liu, Kelli L. Boyd, Sara Kantrow, Ryan C. Splittgerber, Sarah P. Short, Tammy Sobolik, Snjezana Zaja-Milatovic, Kimberly Brown Dahlman, Katayoun I. Amiri, Aixiang Jiang, Pengcheng Lu, Yu Shyr, Darrin D. Stuart, Shawn Levy, Jeffrey A. Sosman, Ann Richmond
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (8): 2184–2198.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-1122
Published: 16 April 2012
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A Gene Expression Signature from Human Breast Cancer Cells with Acquired Hormone Independence Identifies MYC as a Mediator of Antiestrogen Resistance

Todd W. Miller, Justin M. Balko, Zara Ghazoui, Anita Dunbier, Helen Anderson, Mitch Dowsett, Ana M. González-Angulo, Gordon B. Mills, William R. Miller, Huiyun Wu, Yu Shyr, Carlos L. Arteaga
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 2024–2034.
DOI: https://doi.org/10.1158/1078-0432.CCR-10-2567
Published: 31 March 2011
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A Phase II Study of Celecoxib in Combination with Paclitaxel, Carboplatin, and Radiotherapy for Patients with Inoperable Stage IIIA/B Non–Small Cell Lung Cancer

Robert Mutter, Bo Lu, David P. Carbone, Ildiko Csiki, Luigi Moretti, David H. Johnson, Jason D. Morrow, Alan B. Sandler, Yu Shyr, Fei Ye, Hak Choy
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (6): 2158–2165.
DOI: https://doi.org/10.1158/1078-0432.CCR-08-0629
Published: 16 March 2009
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Gene Expression Differences Associated with Human Papillomavirus Status in Head and Neck Squamous Cell Carcinoma

Robbert J.C. Slebos, Yajun Yi, Kim Ely, Jesse Carter, Amy Evjen, Xueqiong Zhang, Yu Shyr, Barbara M. Murphy, Anthony J. Cmelak, Brian B. Burkey, James L. Netterville, Shawn Levy, Wendell G. Yarbrough, Christine H. Chung
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (3): 701–709.
DOI: https://doi.org/10.1158/1078-0432.CCR-05-2017
Published: 07 February 2006
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Targeting Cyclooxygenase-2 in Recurrent Non–Small Cell Lung Cancer: A Phase II Trial of Celecoxib and Docetaxel

Ildiko Csiki, Jason D. Morrow, Alan Sandler, Yu Shyr, John Oates, Myles K. Williams, Thao Dang, David P. Carbone, David H. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (18): 6634–6640.
DOI: https://doi.org/10.1158/1078-0432.CCR-05-0436
Published: 15 September 2005
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A Training-Testing Approach to the Molecular Classification of Resected Non-Small Cell Lung Cancer

Noboru Yamagata, Yu Shyr, Kiyoshi Yanagisawa, Mary Edgerton, Thao P. Dang, Adriana Gonzalez, Sorena Nadaf, Paul Larsen, John R. Roberts, Jonathan C. Nesbitt, Roy Jensen, Shawn Levy, Jason H. Moore, John D. Minna, David P. Carbone
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (13): 4695–4704.
Published: 27 October 2003
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Weekly Irinotecan and Cisplatin in Advanced Non-Small Cell Lung Cancer: A Multicenter Phase II Study

Madan H. Jagasia, Corey J. Langer, David H. Johnson, Furhan Yunus, John S. Rodgers, Larry L. Schlabach, Alan G. Cohen, Yu Shyr, David P. Carbone, Russell F. DeVore
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (1): 68–73.
Published: 01 January 2001
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Treatment with Farnesyl-Protein Transferase Inhibitor Induces Regression of Mammary Tumors in Transforming Growth Factor (TGF) α and TGFα/neu Transgenic Mice by Inhibition of Mitogenic Activity and Induction of Apoptosis

Peter Nørgaard, Brian Law, Heather Joseph, David L. Page, Yu Shyr, Debbie Mays, Jennifer A. Pietenpol, Nancy E. Kohl, Allen Oliff, Robert J. Coffey, Jr., Hans Skovgaard Poulsen, Harold L. Moses
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (1): 35–42.
Published: 01 January 1999
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