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Journal Articles

Mutational Landscape of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Association with Immune Checkpoint Inhibitor Outcomes

Patricia McCoon, Ying Wang, Zhongwu Lai, Qu Zhang, Weimin Li, Sophie Wildsmith, Nassim Morsli, Rajiv Raja, Nicholas Holoweckyj, Jill Walker, Melissa de los Reyes, Ricard Mesía, Lisa Licitra, Robert L. Ferris, Jérôme Fayette, Dan P. Zandberg, Lillian L. Siu, Robert Haddad
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF12.
https://doi.org/10.1158/1078-0432.CCR-24-2198
Published: 15 April 2025
View articletitled, Mutational Landscape of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Association with Immune Checkpoint Inhibitor Outcomes
Open the PDF for Mutational Landscape of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Association with Immune Checkpoint Inhibitor Outcomes in another window
Includes: Supplementary data
Journal Articles

Cladribine Added to Idarubicin and Cytarabine as an Induction Regimen for Patients with De Novo Acute Myeloid Leukemia: A Multicenter, Randomized Phase III Trial

Xiang Zhang, Yue Han, Huiying Qiu, Miaoxinqi Han, Aining Sun, Shengli Xue, Zhengming Jin, Miao Miao, Ying Wang, Chengcheng Fu, Xiaowen Tang, Suning Chen, Caixia Li, Lian Bai, Zhihong Lin, Jun Chen, Haohao Han, Jia Chen, Depei Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (8): 1407–1414.
https://doi.org/10.1158/1078-0432.CCR-24-2437
Published: 14 April 2025
View articletitled, Cladribine Added to Idarubicin and Cytarabine as an Induction Regimen for Patients with De Novo Acute Myeloid Leukemia: A Multicenter, Randomized Phase III Trial
Open the PDF for Cladribine Added to Idarubicin and Cytarabine as an Induction Regimen for Patients with De Novo Acute Myeloid Leukemia: A Multicenter, Randomized Phase III Trial in another window
Includes: Supplementary data
Journal Articles

A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

Andrew L. Coveler, Matthew J. Reilley, Mark Zalupski, Teresa Macarulla, Christos Fountzilas, Mariano Ponz-Sarvisé, Adnan Nagrial, Nataliya V. Uboha, Sophia Frentzas, Michael Overman, Anne Noonan, Wells A. Messersmith, Nick Pavlakis, Niharika B. Mettu, Ina Bisha, Ying Wang, Paul Smith, Elina Murtomaki, Agata A. Bielska, Veronique Bragulat, Zachary A. Cooper, Rakesh Kumar, David R. Spigel
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (20): 4609–4617.
https://doi.org/10.1158/1078-0432.CCR-24-0499
Published: 15 October 2024
View articletitled, A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma
Open the PDF for A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients

Bo Zheng, Xiao-Long Liu, Rong Fan, Jian Bai, Hao Wen, Lu-Tao Du, Guo-Qing Jiang, Chun-Ying Wang, Xiao-Tang Fan, Yi-Nong Ye, Yun-Song Qian, Ying-Chao Wang, Gao-Jing Liu, Guo-Hong Deng, Feng Shen, He-Ping Hu, Hui Wang, Qing-Zheng Zhang, Lan-Lan Ru, Jing Zhang, Yan-Hang Gao, Jie Xia, Hua-Dong Yan, Min-Feng Liang, Yan-Long Yu, Fu-Ming Sun, Yu-Jing Gao, Jian Sun, Chun-Xiu Zhong, Yin Wang, Fei Kong, Jin-Ming Chen, Dan Zheng, Yuan Yang, Chuan-Xin Wang, Lin Wu, Jin-Lin Hou, Jing-Feng Liu, Hong-Yang Wang, Lei Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3772–3783.
https://doi.org/10.1158/1078-0432.CCR-21-0002
Published: 01 July 2021
View articletitled, The Landscape of Cell-Free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients
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Includes: Supplementary data
Journal Articles

Neratinib-Plus-Cetuximab in Quadruple-WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study

Samuel A. Jacobs, James J. Lee, Thomas J. George, James L. Wade, III, Philip J. Stella, Ding Wang, Ashwin R. Sama, Fanny Piette, Katherine L. Pogue-Geile, Rim S. Kim, Patrick G. Gavin, Corey Lipchik, Huichen Feng, Ying Wang, Melanie Finnigan, Brian F. Kiesel, Jan H. Beumer, Norman Wolmark, Peter C. Lucas, Carmen J. Allegra, Ashok Srinivasan
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1612–1622.
https://doi.org/10.1158/1078-0432.CCR-20-1831
Published: 15 March 2021
View articletitled, Neratinib-Plus-Cetuximab in Quadruple-WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study
Open the PDF for Neratinib-Plus-Cetuximab in Quadruple-WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study in another window
Includes: Supplementary data
Journal Articles

Randomized Trial of Intermediate-dose Cytarabine in Induction and Consolidation Therapy in Adults with Acute Myeloid Leukemia

Hui Wei, Ying Wang, Robert Peter Gale, Dong Lin, Chunlin Zhou, Bingcheng Liu, Shaowei Qiu, Runxia Gu, Yan Li, Xingli Zhao, Shuning Wei, Benfa Gong, Kaiqi Liu, Xiaoyuan Gong, Yuntao Liu, Guangji Zhang, Zhen Song, Yang Wang, Wei Li, Yingchang Mi, Jianxiang Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3154–3161.
https://doi.org/10.1158/1078-0432.CCR-19-3433
Published: 01 July 2020
View articletitled, Randomized Trial of Intermediate-dose Cytarabine in Induction and Consolidation Therapy in Adults with Acute Myeloid Leukemia
Open the PDF for Randomized Trial of Intermediate-dose Cytarabine in Induction and Consolidation Therapy in Adults with Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Activated and Exhausted MAIT Cells Foster Disease Progression and Indicate Poor Outcome in Hepatocellular Carcinoma

Meng Duan, Shyamal Goswami, Jie-Yi Shi, Lin-Jie Wu, Xiao-Ying Wang, Jia-Qiang Ma, Zhao Zhang, Yang Shi, Li-Jie Ma, Shu Zhang, Rui-Bin Xi, Ya Cao, Jian Zhou, Jia Fan, Xiao-Ming Zhang, Qiang Gao
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (11): 3304–3316.
https://doi.org/10.1158/1078-0432.CCR-18-3040
Published: 03 June 2019
View articletitled, Activated and Exhausted MAIT Cells Foster Disease Progression and Indicate Poor Outcome in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer

Fan Li, Yan Xu, Bovey Liu, Pankaj Kumar Singh, Wei Zhao, Jiankang Jin, Guangchun Han, Ailing W. Scott, Xiaochuan Dong, Longfei Huo, Lang Ma, Melissa Pool Pizzi, Ying Wang, Yuan Li, Kazuto Harada, Min Xie, Heath D. Skinner, Sheng Ding, Linghua Wang, Sunil Krishnan, Randy L. Johnson, Shumei Song, Jaffer A. Ajani
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (7): 2264–2277.
https://doi.org/10.1158/1078-0432.CCR-18-1029
Published: 01 April 2019
View articletitled, YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer
Open the PDF for YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer in another window
Includes: Supplementary data
Journal Articles

Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine–Paracrine Loop

Ying Wang, Jianing Chen, Linbin Yang, Jiaqian Li, Wei Wu, Min Huang, Ling Lin, Shicheng Su
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1957–1969.
https://doi.org/10.1158/1078-0432.CCR-18-2544
Published: 15 March 2019
View articletitled, Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine–Paracrine Loop
Open the PDF for Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine–Paracrine Loop in another window
Includes: Supplementary data
Journal Articles

TGFβ1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy

Ye Tao, Erich M. Sturgis, Zhigang Huang, Ying Wang, Peng Wei, Jennifer Rui Wang, Qingyi Wei, Guojun Li
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (9): 2225–2233.
https://doi.org/10.1158/1078-0432.CCR-17-1904
Published: 30 April 2018
View articletitled, TGFβ1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy
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Journal Articles

Functional Role of a Novel Long Noncoding RNA TTN-AS1 in Esophageal Squamous Cell Carcinoma Progression and Metastasis

Chenyu Lin, Shengnan Zhang, Ying Wang, Yuanshu Wang, Edouard Nice, Changying Guo, Erhao Zhang, Liting Yu, Mengwei Li, Chen Liu, Lirong Hu, Jingchao Hao, Weiyan Qi, Hanmei Xu
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 486–498.
https://doi.org/10.1158/1078-0432.CCR-17-1851
Published: 15 January 2018
View articletitled, Functional Role of a Novel Long Noncoding RNA TTN-AS1 in Esophageal Squamous Cell Carcinoma Progression and Metastasis
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Includes: Supplementary data
Journal Articles

Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma

Jie-Yi Shi, Qiang Gao, Zhi-Chao Wang, Jian Zhou, Xiao-Ying Wang, Zhi-Hui Min, Ying-Hong Shi, Guo-Ming Shi, Zhen-Bin Ding, Ai-Wu Ke, Zhi Dai, Shuang-Jian Qiu, Kang Song, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5994–6005.
https://doi.org/10.1158/1078-0432.CCR-12-3497
Published: 31 October 2013
View articletitled, Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma
Open the PDF for Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes

Hiroko Masuda, Keith A. Baggerly, Ying Wang, Ya Zhang, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam, Vicente Valero, Brian D. Lehmann, Jennifer A. Pietenpol, Gabriel N. Hortobagyi, W. Fraser Symmans, Naoto T. Ueno
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2013) 19 (19): 5533–5540.
https://doi.org/10.1158/1078-0432.CCR-13-0799
Published: 01 October 2013
View articletitled, Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes
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Includes: Supplementary data
Journal Articles

Eribulin Mesylate for the Treatment of Patients with Refractory Metastatic Breast Cancer: Use of a “Physician's Choice” Control Arm in a Randomized Approval Trial

Martha Donoghue, Steven J. Lemery, Weishi Yuan, Kun He, Rajeshwari Sridhara, Stacy Shord, Hong Zhao, Anshu Marathe, Lori Kotch, Josephine Jee, Ying Wang, Liang Zhou, William M. Adams, Vaishali Jarral, Anne Pilaro, Richard Lostritto, Joseph E. Gootenberg, Patricia Keegan, Richard Pazdur
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (6): 1496–1505.
https://doi.org/10.1158/1078-0432.CCR-11-2149
Published: 14 March 2012
View articletitled, Eribulin Mesylate for the Treatment of Patients with Refractory Metastatic Breast Cancer: Use of a “Physician's Choice” Control Arm in a Randomized Approval Trial
Open the PDF for Eribulin Mesylate for the Treatment of Patients with Refractory Metastatic Breast Cancer: Use of a “Physician's Choice” Control Arm in a Randomized Approval Trial in another window
Journal Articles

Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation

Zhen-Bin Ding, Bo Hui, Ying-Hong Shi, Jian Zhou, Yuan-Fei Peng, Cheng-Yu Gu, Hua Yang, Guo-Ming Shi, Ai-Wu Ke, Xiao-Ying Wang, Kang Song, Zhi Dai, Ying-Hao Shen, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (19): 6229–6238.
https://doi.org/10.1158/1078-0432.CCR-11-0816
Published: 02 October 2011
View articletitled, Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation
Open the PDF for Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation in another window
Includes: Supplementary data
Journal Articles

Cyclin D1 Splice Variants: Polymorphism, Risk, and Isoform-Specific Regulation in Prostate Cancer

Clay E.S. Comstock, Michael A. Augello, Ruth Pe Benito, Jason Karch, Thai H. Tran, Fransiscus E. Utama, Elizabeth A. Tindall, Ying Wang, Craig J. Burd, Eric M. Groh, Hoa N. Hoang, Graham G. Giles, Gianluca Severi, Vanessa M. Hayes, Brian E. Henderson, Loic Le Marchand, Laurence N. Kolonel, Christopher A. Haiman, Raffaele Baffa, Leonard G. Gomella, Erik S. Knudsen, Hallgeir Rui, Susan M. Henshall, Robert L. Sutherland, Karen E. Knudsen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (17): 5338–5349.
https://doi.org/10.1158/1078-0432.CCR-08-2865
Published: 31 August 2009
View articletitled, Cyclin D1 Splice Variants: Polymorphism, Risk, and Isoform-Specific Regulation in Prostate Cancer
Open the PDF for Cyclin D1 Splice Variants: Polymorphism, Risk, and Isoform-Specific Regulation in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery

Xin-Rong Yang, Yang Xu, Bin Yu, Jian Zhou, Jia-Chu Li, Shuang-Jian Qiu, Ying-Hong Shi, Xiao-Ying Wang, Zhi Dai, Guo-Ming Shi, Bin Wu, Li-Ming Wu, Guo-Huan Yang, Bo-Heng Zhang, Wen-Xin Qin, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (17): 5518–5527.
https://doi.org/10.1158/1078-0432.CCR-09-0151
Published: 31 August 2009
View articletitled, CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery
Open the PDF for CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery in another window
Includes: Supplementary data
Journal Articles

Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

Qiang Gao, Xiao-Ying Wang, Shuang-Jian Qiu, Ichiro Yamato, Masayuki Sho, Yoshiyuki Nakajima, Jian Zhou, Bai-Zhou Li, Ying-Hong Shi, Yong-Sheng Xiao, Yang Xu, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (3): 971–979.
https://doi.org/10.1158/1078-0432.CCR-08-1608
Published: 02 February 2009
View articletitled, Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma
Open the PDF for Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Tagging Single Nucleotide Polymorphisms in Phosphoinositide-3-Kinase–Related Protein Kinase Genes Involved in DNA Damage “Checkpoints” and Lung Cancer Susceptibility

Zhibin Hu, Hongliang Liu, Haifeng Wang, Ruifen Miao, Weiwei Sun, Guangfu Jin, Ying Wang, Hongxia Ma, Li Jin, Qingyi Wei, Daru Lu, Wei Huang, Hongbing Shen
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2887–2891.
https://doi.org/10.1158/1078-0432.CCR-07-1822
Published: 01 May 2008
View articletitled, Tagging Single Nucleotide Polymorphisms in Phosphoinositide-3-Kinase–Related Protein Kinase Genes Involved in DNA Damage “Checkpoints” and Lung Cancer Susceptibility
Open the PDF for Tagging Single Nucleotide Polymorphisms in Phosphoinositide-3-Kinase–Related Protein Kinase Genes Involved in DNA Damage “Checkpoints” and Lung Cancer Susceptibility in another window
Journal Articles

Two Single-Nucleotide Polymorphisms with Linkage Disequilibrium in the Human Programmed Cell Death 5 Gene 5′ Regulatory Region Affect Promoter Activity and the Susceptibility of Chronic Myelogenous Leukemia in Chinese Population

Xi Ma, Guorui Ruan, Ying Wang, Qiyan Li, Ping Zhu, Ya-Zhen Qin, Jin-Lan Li, Yan-Rong Liu, Dalong Ma, Hongshan Zhao
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (24): 8592–8599.
https://doi.org/10.1158/1078-0432.CCR-05-0039
Published: 16 December 2005
View articletitled, Two Single-Nucleotide Polymorphisms with Linkage Disequilibrium in the Human Programmed Cell Death 5 Gene 5′ Regulatory Region Affect Promoter Activity and the Susceptibility of Chronic Myelogenous Leukemia in Chinese Population
Open the PDF for Two Single-Nucleotide Polymorphisms with Linkage Disequilibrium in the Human Programmed Cell Death 5 Gene 5′ Regulatory Region Affect Promoter Activity and the Susceptibility of Chronic Myelogenous Leukemia in Chinese Population in another window