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Journal Articles

hENT1 Expression Predicts Response to Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Ductal Adenocarcinoma

Sheron Perera, Gun Ho Jang, Yifan Wang, Deirdre Kelly, Michael Allen, Amy Zhang, Robert E. Denroche, Anna Dodd, Stephanie Ramotar, Shawn Hutchinson, Mustapha Tehfe, Ravi Ramjeesingh, James Biagi, Bernard Lam, Julie Wilson, Sandra E. Fischer, George Zogopoulos, Faiyaz Notta, Steven Gallinger, Robert C. Grant, Jennifer J. Knox, Grainne M. O'Kane
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (23): 5115–5120.
https://doi.org/10.1158/1078-0432.CCR-22-2576
Published: 01 December 2022
View article titled, hENT1 Expression Predicts Response to Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Ductal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Correction: GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer

Grainne M. O'Kane, Barbara T. Grünwald, Gun-Ho Jang, Mehdi Masoomian, Sarah Picardo, Robert C. Grant, Robert E. Denroche, Amy Zhang, Yifan Wang, Jessica K. Miller, Bernard Lam, Paul M. Krzyzanowski, Ilinca M. Lungu, John M.S. Bartlett, Melanie Peralta, Foram Vyas, Rama Khokha, James Biagi, Dianne Chadwick, Stephanie Ramotar, Shawn Hutchinson, Anna Dodd, Julie M. Wilson, Faiyaz Notta, George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2715.
https://doi.org/10.1158/1078-0432.CCR-22-1272
Published: 13 June 2022
View article titled, Correction: GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer
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Journal Articles

A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination–deficient Pancreatic Cancer

Yifan Wang, Jin Yong Patrick Park, Alain Pacis, Robert E. Denroche, Gun Ho Jang, Amy Zhang, Adeline Cuggia, Celine Domecq, Jean Monlong, Maria Raitses-Gurevich, Robert C. Grant, Ayelet Borgida, Spring Holter, Chani Stossel, Simeng Bu, Mehdi Masoomian, Ilinca M. Lungu, John M.S. Bartlett, Julie M. Wilson, Zu-Hua Gao, Yasser Riazalhosseini, Jamil Asselah, Nathaniel Bouganim, Tatiana Cabrera, Louis-Martin Boucher, David Valenti, James Biagi, Celia M.T. Greenwood, Paz Polak, William D. Foulkes, Talia Golan, Grainne M. O'Kane, Sandra E. Fischer, Jennifer J. Knox, Steven Gallinger, George Zogopoulos
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (20): 5462–5476.
https://doi.org/10.1158/1078-0432.CCR-20-1439
Published: 15 October 2020
View article titled, A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination–deficient Pancreatic Cancer
Open the PDF for A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination–deficient Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer

Grainne M. O’Kane, Barbara T. Grünwald, Gun-Ho Jang, Mehdi Masoomian, Sarah Picardo, Robert C. Grant, Robert E. Denroche, Amy Zhang, Yifan Wang, Jessica K. Miller, Bernard Lam, Paul M. Krzyzanowski, Ilinca M. Lungu, John M.S. Bartlett, Melanie Peralta, Foram Vyas, Rama Khokha, James Biagi, Dianne Chadwick, Stephanie Ramotar, Shawn Hutchinson, Anna Dodd, Julie M. Wilson, Faiyaz Notta, George Zogopoulos, Steven Gallinger, Jennifer J. Knox, Sandra E. Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18): 4901–4910.
https://doi.org/10.1158/1078-0432.CCR-19-3724
Published: 01 September 2020
View article titled, GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

A Four-Chemokine Signature Is Associated with a T-cell–Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer

Joan M. Romero, Barbara Grünwald, Gun-Ho Jang, Prashant P. Bavi, Aaditeya Jhaveri, Mehdi Masoomian, Sandra E. Fischer, Amy Zhang, Robert E. Denroche, Ilinca M. Lungu, Angela De Luca, John M.S. Bartlett, Jing Xu, Niandong Li, Sharon Dhaliwal, Sheng-Ben Liang, Dianne Chadwick, Foram Vyas, Peter Bronsert, Rama Khokha, Tracy L. McGaha, Faiyaz Notta, Pamela S. Ohashi, Susan J. Done, Grainne M. O'Kane, Julie M. Wilson, Jennifer J. Knox, Ashton Connor, Yifan Wang, George Zogopoulos, Steven Gallinger
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (8): 1997–2010.
https://doi.org/10.1158/1078-0432.CCR-19-2803
Published: 15 April 2020
View article titled, A Four-Chemokine Signature Is Associated with a T-cell–Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Low-Dose Anti-Angiogenic Therapy Sensitizes Breast Cancer to PD-1 Blockade

Qian Li, Yifan Wang, Weijuan Jia, Heran Deng, Guangdi Li, Weiye Deng, Jiewen Chen, Betty Y.S. Kim, Wen Jiang, Qiang Liu, Jieqiong Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (7): 1712–1724.
https://doi.org/10.1158/1078-0432.CCR-19-2179
Published: 01 April 2020
View article titled, Low-Dose Anti-Angiogenic Therapy Sensitizes Breast Cancer to PD-1 Blockade
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Includes: Supplementary data
Journal Articles

Abstract AP30: BRCA1 INTRON RETENTION GENERATES TRUNCATED PROTEINS THAT AVOID BRCT MUTATION MISFOLDING AND PROMOTE PARP INHIBITOR RESISTANCE

Yifan Wang, Andrea J. Bernhardy, Joseph Nacson, John J. Krais, Yin-Fei Tan, Michael Slifker, Suraj Peri, Neil Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22_Supplement): AP30.
https://doi.org/10.1158/1557-3265.OVCASYMP18-AP30
Published: 15 November 2019
View article titled, Abstract AP30: BRCA1 INTRON RETENTION GENERATES TRUNCATED PROTEINS THAT AVOID BRCT MUTATION MISFOLDING AND PROMOTE PARP INHIBITOR RESISTANCE
Journal Articles

The Reciprocity between Radiotherapy and Cancer Immunotherapy

Yifan Wang, Zhi-Gang Liu, Hengfeng Yuan, Weiye Deng, Jing Li, Yuhui Huang, Betty Y.S. Kim, Michael D. Story, Wen Jiang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1709–1717.
https://doi.org/10.1158/1078-0432.CCR-18-2581
Published: 15 March 2019
View article titled, The Reciprocity between Radiotherapy and Cancer Immunotherapy
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Journal Articles

Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non–Small Cell Lung Cancer

Yifan Wang, Nan Li, Wen Jiang, Weiye Deng, Rui Ye, Cai Xu, Yawei Qiao, Amrish Sharma, Ming Zhang, Mien-Chie Hung, Steven H. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (22): 5744–5756.
https://doi.org/10.1158/1078-0432.CCR-18-1489
Published: 15 November 2018
View article titled, Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Abstract A07: 53BP1-driven homologous recombination and PARP inhibitor resistance requires intact BRCA1-PALB2 association

Joseph Nacson, Andrea Bernhardy, Xiang Hua, Yifan Wang, John Krais, Neil Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15_Supplement): A07.
https://doi.org/10.1158/1557-3265.OVCA17-A07
Published: 01 August 2018
View article titled, Abstract A07: 53BP1-driven homologous recombination and PARP inhibitor resistance requires intact BRCA1-PALB2 association
Journal Articles

RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer

Yifan Wang, Jayanthi Gudikote, Uma Giri, Jun Yan, Weiye Deng, Rui Ye, Wen Jiang, Nan Li, Brian P. Hobbs, Jing Wang, Stephen G. Swisher, Junya Fujimoto, Ignacio I. Wistuba, Ritsuko Komaki, John V. Heymach, Steven H. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 341–350.
https://doi.org/10.1158/1078-0432.CCR-17-1455
Published: 15 January 2018
View article titled, RAD50 Expression Is Associated with Poor Clinical Outcomes after Radiotherapy for Resected Non–small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Abstract AP29: BRCA1 RING DOMAIN–DEFICIENT PROTEINS PROMOTE PARP INHIBITOR AND PLATINUM RESISTANCE

Yifan Wang, John J. Krais, Andrea J. Bernhardy, Emmanuelle Nicolas, Kathy Q. Cai, Maria I. Harrell, Hyoung H. Kim, Erin George, Elizabeth M. Swisher, Fiona Simpkins, Neil Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11_Supplement): AP29.
https://doi.org/10.1158/1557-3265.OVCASYMP16-AP29
Published: 31 May 2017
View article titled, Abstract AP29: BRCA1 RING DOMAIN–DEFICIENT PROTEINS PROMOTE PARP INHIBITOR AND PLATINUM RESISTANCE
Journal Articles

Hsp90 Inhibitor Ganetespib Sensitizes Non–Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation

Yifan Wang, Hui Liu, Lixia Diao, Adam Potter, Jianhu Zhang, Yawei Qiao, Jing Wang, David A. Proia, Ramesh Tailor, Ritsuko Komaki, Steven H. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (23): 5876–5886.
https://doi.org/10.1158/1078-0432.CCR-15-2190
Published: 30 November 2016
View article titled, Hsp90 Inhibitor Ganetespib Sensitizes Non–Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation
Open the PDF for Hsp90 Inhibitor Ganetespib Sensitizes Non–Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation in another window
Includes: Supplementary data