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Journal Articles

Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting

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Marco Ventin, Giulia Cattaneo, Shahrzad Arya, Jingyu Jia, Maria C. Gelmi, Yi Sun, Luke Maggs, Bruce R. Ksander, Robert M. Verdijk, Genevieve M. Boland, Russell W. Jenkins, Rizwan Haq, Martine J. Jager, Xinhui Wang, Sandra Ryeom, Cristina R. Ferrone
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (15): 3243–3258.
https://doi.org/10.1158/1078-0432.CCR-24-0071
Published: 01 August 2024
View articletitled, Chimeric Antigen Receptor T Cell with an Inducible Caspase-9 Suicide Gene Eradicates Uveal Melanoma Liver Metastases via B7-H3 Targeting
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Includes: Supplementary data
Journal Articles

Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma

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Marc Wehrli, Samantha Guinn, Filippo Birocchi, Adam Kuo, Yi Sun, Rebecca C. Larson, Antonio J. Almazan, Irene Scarfò, Amanda A. Bouffard, Stefanie R. Bailey, Praju Vikas Anekal, Paula Montero Llopis, Linda T. Nieman, Yuhui Song, Katherine H. Xu, Trisha R. Berger, Michael C. Kann, Mark B. Leick, Harrison Silva, Diego Salas-Benito, Tamina Kienka, Korneel Grauwet, Todd D. Armstrong, Rui Zhang, Qingfeng Zhu, Juan Fu, Andrea Schmidts, Felix Korell, Max Jan, Bryan D. Choi, Andrew S. Liss, Genevieve M. Boland, David T. Ting, Richard A. Burkhart, Russell W. Jenkins, Lei Zheng, Elizabeth M. Jaffee, Jacquelyn W. Zimmerman, Marcela V. Maus
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (9): 1859–1877.
https://doi.org/10.1158/1078-0432.CCR-23-3841
Published: 01 May 2024
View articletitled, Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma
Open the PDF for Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma in another window
Includes: Multimedia, Supplementary data
Journal Articles

HMGA2–FOXL2 Axis Regulates Metastases and Epithelial-to-Mesenchymal Transition of Chemoresistant Gastric Cancer

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Jiaqiang Dong, Rui Wang, Gui Ren, Xiaowei Li, Jingbo Wang, Yi Sun, Jie Liang, Yongzhan Nie, Kaichun Wu, Bin Feng, Yulong Shang, Daiming Fan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (13): 3461–3473.
https://doi.org/10.1158/1078-0432.CCR-16-2180
Published: 02 July 2017
View articletitled, HMGA2–FOXL2 Axis Regulates Metastases and Epithelial-to-Mesenchymal Transition of Chemoresistant Gastric Cancer
Open the PDF for HMGA2–FOXL2 Axis Regulates Metastases and Epithelial-to-Mesenchymal Transition of Chemoresistant Gastric Cancer in another window
Includes: Supplementary data
Journal Articles

Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage

Free
Weihua Zhou, Jie Xu, Haomin Li, Ming Xu, Zhijian J. Chen, Wenyi Wei, Zhenqiang Pan, Yi Sun
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (4): 1104–1116.
https://doi.org/10.1158/1078-0432.CCR-16-1585
Published: 14 February 2017
View articletitled, Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage
Open the PDF for Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage in another window
Includes: Supplementary data
Journal Articles

Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair

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Dongping Wei, Leslie A. Parsels, David Karnak, Mary A. Davis, Joshua D. Parsels, Amanda C. Marsh, Lili Zhao, Jonathan Maybaum, Theodore S. Lawrence, Yi Sun, Meredith A. Morgan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (16): 4422–4432.
https://doi.org/10.1158/1078-0432.CCR-13-0788
Published: 13 August 2013
View articletitled, Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair
Open the PDF for Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair in another window
Includes: Supplementary data
Journal Articles

Validation of SAG/RBX2/ROC2 E3 Ubiquitin Ligase as an Anticancer and Radiosensitizing Target

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Lijun Jia, Jie Yang, Xinbao Hao, Min Zheng, Hongbin He, Xiufang Xiong, Liang Xu, Yi Sun
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (3): 814–824.
https://doi.org/10.1158/1078-0432.CCR-09-1592
Published: 01 February 2010
View articletitled, Validation of SAG/RBX2/ROC2 E3 Ubiquitin Ligase as an Anticancer and Radiosensitizing Target
Open the PDF for Validation of SAG/RBX2/ROC2 E3 Ubiquitin Ligase as an Anticancer and Radiosensitizing Target in another window
Includes: Supplementary data
Journal Articles

Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy

Free
Ming Zhu Fang, Dapeng Chen, Yi Sun, Zhe Jin, Judith K. Christman, Chung S. Yang
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (19): 7033–7041.
https://doi.org/10.1158/1078-0432.CCR-05-0406
Published: 03 October 2005
View articletitled, Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy
Open the PDF for Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy in another window
Journal Articles

The Investigational New Drug XK469 Induces G2-M Cell Cycle Arrest by p53-dependent and -independent Pathways

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Zhenhua Ding, Ralph E. Parchment, Patricia M. LoRusso, Jun-Ying Zhou, Jun Li, Theodore S. Lawrence, Yi Sun, Gen Sheng Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (11): 3336–3342.
Published: 01 November 2001
View articletitled, The Investigational New Drug XK469 Induces G2-M Cell Cycle Arrest by p53-dependent and -independent Pathways
Open the PDF for The Investigational New Drug XK469 Induces G2-M Cell Cycle Arrest by p53-dependent and -independent Pathways in another window