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Yasuhiko Nishioka
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Journal Articles

Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor–Induced Tyrosine Kinase Inhibitor Resistance in EGFR Mutant Lung Cancer

Wei Wang, Qi Li, Shinji Takeuchi, Tadaaki Yamada, Hitomi Koizumi, Takahiro Nakamura, Kunio Matsumoto, Naofumi Mukaida, Yasuhiko Nishioka, Saburo Sone, Takayuki Nakagawa, Toshimitsu Uenaka, Seiji Yano
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (6): 1663–1671.
https://doi.org/10.1158/1078-0432.CCR-11-1171
Published: 14 March 2012
View article titled, Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor–Induced Tyrosine Kinase Inhibitor Resistance in <em>EGFR</em> Mutant Lung Cancer
Open the PDF for Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor–Induced Tyrosine Kinase Inhibitor Resistance in <em>EGFR</em> Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Transient PI3K Inhibition Induces Apoptosis and Overcomes HGF-Mediated Resistance to EGFR-TKIs in EGFR Mutant Lung Cancer

Ivan S. Donev, Wei Wang, Tadaaki Yamada, Qi Li, Shinji Takeuchi, Kunio Matsumoto, Takao Yamori, Yasuhiko Nishioka, Saburo Sone, Seiji Yano
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (8): 2260–2269.
https://doi.org/10.1158/1078-0432.CCR-10-1993
Published: 14 April 2011
View article titled, Transient PI3K Inhibition Induces Apoptosis and Overcomes HGF-Mediated Resistance to EGFR-TKIs in <em>EGFR</em> Mutant Lung Cancer
Open the PDF for Transient PI3K Inhibition Induces Apoptosis and Overcomes HGF-Mediated Resistance to EGFR-TKIs in <em>EGFR</em> Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in EGFR-T790M Mutant Lung Cancer

Tadaaki Yamada, Kunio Matsumoto, Wei Wang, Qi Li, Yasuhiko Nishioka, Yoshitaka Sekido, Saburo Sone, Seiji Yano
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (1): 174–183.
https://doi.org/10.1158/1078-0432.CCR-09-1204
Published: 04 January 2010
View article titled, Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in <em>EGFR</em>-T790M Mutant Lung Cancer
Open the PDF for Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in <em>EGFR</em>-T790M Mutant Lung Cancer in another window
Includes: Supplementary data
Journal Articles

E7080, a Multi–Tyrosine Kinase Inhibitor, Suppresses the Progression of Malignant Pleural Mesothelioma with Different Proangiogenic Cytokine Production Profiles

Kenji Ikuta, Seiji Yano, Van The Trung, Masaki Hanibuchi, Hisatsugu Goto, Qi Li, Wei Wang, Tadaaki Yamada, Hirokazu Ogino, Soji Kakiuchi, Hisanori Uehara, Yoshitaka Sekido, Toshimitsu Uenaka, Yasuhiko Nishioka, Saburo Sone
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7229–7237.
https://doi.org/10.1158/1078-0432.CCR-09-1980
Published: 30 November 2009
View article titled, E7080, a Multi–Tyrosine Kinase Inhibitor, Suppresses the Progression of Malignant Pleural Mesothelioma with Different Proangiogenic Cytokine Production Profiles
Open the PDF for E7080, a Multi–Tyrosine Kinase Inhibitor, Suppresses the Progression of Malignant Pleural Mesothelioma with Different Proangiogenic Cytokine Production Profiles in another window
Journal Articles

Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Wei Wang, Qi Li, Tadaaki Yamada, Kunio Matsumoto, Isao Matsumoto, Makoto Oda, Go Watanabe, Yoshiyuki Kayano, Yasuhiko Nishioka, Saburo Sone, Seiji Yano
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (21): 6630–6638.
https://doi.org/10.1158/1078-0432.CCR-09-1001
Published: 02 November 2009
View article titled, Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
Open the PDF for Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in another window
Includes: Supplementary data
Journal Articles

The Therapeutic Efficacy of Anti–Vascular Endothelial Growth Factor Antibody, Bevacizumab, and Pemetrexed against Orthotopically Implanted Human Pleural Mesothelioma Cells in Severe Combined Immunodeficient Mice

Qi Li, Seiji Yano, Hirokazu Ogino, Wei Wang, Hisanori Uehara, Yasuhiko Nishioka, Saburo Sone
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5918–5925.
https://doi.org/10.1158/1078-0432.CCR-07-0501
Published: 01 October 2007
View article titled, The Therapeutic Efficacy of Anti–Vascular Endothelial Growth Factor Antibody, Bevacizumab, and Pemetrexed against Orthotopically Implanted Human Pleural Mesothelioma Cells in Severe Combined Immunodeficient Mice
Open the PDF for The Therapeutic Efficacy of Anti–Vascular Endothelial Growth Factor Antibody, Bevacizumab, and Pemetrexed against Orthotopically Implanted Human Pleural Mesothelioma Cells in Severe Combined Immunodeficient Mice in another window