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Journal Articles

SAR-096: Phase II Clinical Trial of Ribociclib in Combination with Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)

Sujana Movva, Sahar Matloob, Elizabeth A. Handorf, Edwin Choy, Priscilla Merriam, Douglas B. Flieder, Kathy Q. Cai, Yan Zhou, Eric D. Tetzlaff, Cheyenne Pagan, Emma Barker, Rosanna Veggeberg, Delia Zumpano, Lori Rink, Margaret von Mehren, Suzanne George
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (2): 315–322.
https://doi.org/10.1158/1078-0432.CCR-23-2469
Published: 17 January 2024
View article titled, SAR-096: Phase II Clinical Trial of Ribociclib in Combination with Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)
Open the PDF for SAR-096: Phase II Clinical Trial of Ribociclib in Combination with Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS) in another window
Includes: Supplementary data
Journal Articles

First-in-Maintenance Therapy for Localized High-Grade Osteosarcoma: An Open-Label Phase I/II Trial of the Anti–PD-L1 Antibody ZKAB001

Yan Zhou, Qingcheng Yang, Yang Dong, Tong Ji, Bing Zhang, Cheng Yang, Shuier Zheng, Lina Tang, Chenliang Zhou, Guowei Qian, Yujing Huang, Wenxi Yu, Hongtao Li, Yonggang Wang, Aina He, Zan Shen, Qiyuan Bao, Yingqi Hua, Hongyu Bai, Jiayi Zhao, Xiaoyi Li, Xiangrong Dai, Jianjun Zhang, Haiyan Hu, Yang Yao
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (4): 764–774.
https://doi.org/10.1158/1078-0432.CCR-22-2470
Published: 16 February 2023
View article titled, First-in-Maintenance Therapy for Localized High-Grade Osteosarcoma: An Open-Label Phase I/II Trial of the Anti–PD-L1 Antibody ZKAB001
Open the PDF for First-in-Maintenance Therapy for Localized High-Grade Osteosarcoma: An Open-Label Phase I/II Trial of the Anti–PD-L1 Antibody ZKAB001 in another window
Includes: Supplementary data
Journal Articles

Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial

Zhanjie Zhang, Bian Wu, Gang Peng, Guixiang Xiao, Jing Huang, Qian Ding, Chengzhang Yang, Xingao Xiong, Hui Ma, Liangliang Shi, Jinsong Yang, Xiaohua Hong, Jielin Wei, You Qin, Chao Wan, Yi Zhong, Yan Zhou, Xueyan Zhao, Yangming Leng, Tao Zhang, Gang Wu, Min Yao, Xiaomeng Zhang, Kunyu Yang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3268–3276.
https://doi.org/10.1158/1078-0432.CCR-22-0666
Published: 02 August 2022
View article titled, Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial
Open the PDF for Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial in another window
Includes: Supplementary data
Journal Articles

A20 and RBX1 Regulate Brentuximab Vedotin Sensitivity in Hodgkin Lymphoma Models

Wei Wei, Yuquan Lin, Zhihui Song, Wenming Xiao, Liqi Chen, Jiejing Yin, Yan Zhou, Stefan K. Barta, Michael Petrus, Thomas A. Waldmann, Yibin Yang
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15): 4093–4106.
https://doi.org/10.1158/1078-0432.CCR-19-4137
Published: 03 August 2020
View article titled, A20 and RBX1 Regulate Brentuximab Vedotin Sensitivity in Hodgkin Lymphoma Models
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Includes: Supplementary data
Journal Articles

CKLF1 Enhances Inflammation-Mediated Carcinogenesis and Prevents Doxorubicin-Induced Apoptosis via IL6/STAT3 Signaling in HCC

Youyi Liu, Lijuan Liu, Yan Zhou, Ping Zhou, Qiujin Yan, Xiaobei Chen, Shuang Ding, Fan Zhu
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 4141–4154.
https://doi.org/10.1158/1078-0432.CCR-18-3510
Published: 01 July 2019
View article titled, CKLF1 Enhances Inflammation-Mediated Carcinogenesis and Prevents Doxorubicin-Induced Apoptosis via IL6/STAT3 Signaling in HCC
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Includes: Supplementary data
Journal Articles

Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma

Wei Guo, Yun-Fan Sun, Min-Na Shen, Xiao-Lu Ma, Jiong Wu, Chun-Yan Zhang, Yan Zhou, Yang Xu, Bo Hu, Min Zhang, Gang Wang, Wei-Qin Chen, Lin Guo, Ren-Quan Lu, Chao-Hui Zhou, Xin Zhang, Ying-Hong Shi, Shuang-jian Qiu, Bai-shen Pan, Ya Cao, Jian Zhou, Xin-Rong Yang, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (9): 2203–2213.
https://doi.org/10.1158/1078-0432.CCR-17-1753
Published: 30 April 2018
View article titled, Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract A02: Succinate dehydrogenase deficiency in a PDGFRA mutated gastrointestinal stromal tumor

Martin G. Belinsky, Lori Rink, Kathy K. Cai, Biao Luo, Yan Zhou, Margaret von Mehren
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2_Supplement): A02.
https://doi.org/10.1158/1557-3265.SARCOMAS17-A02
Published: 15 January 2018
View article titled, Abstract A02: Succinate dehydrogenase deficiency in a PDGFRA mutated gastrointestinal stromal tumor
Journal Articles

Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor

Phillip Zook, Harsh B. Pathak, Martin G. Belinsky, Lawrence Gersz, Karthik Devarajan, Yan Zhou, Andrew K. Godwin, Margaret von Mehren, Lori Rink
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (1): 171–180.
https://doi.org/10.1158/1078-0432.CCR-16-0529
Published: 02 January 2017
View article titled, Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor
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Includes: Supplementary data
Journal Articles

Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3–MYC Interactions as a Target in Pancreatic Cancer

Natalya Beglyarova, Eugenia Banina, Yan Zhou, Ramilia Mukhamadeeva, Grigorii Andrianov, Egor Bobrov, Elena Lysenko, Natalya Skobeleva, Linara Gabitova, Diana Restifo, Max Pressman, Ilya G. Serebriiskii, John P. Hoffman, Keren Paz, Diana Behrens, Vladimir Khazak, Sandra A. Jablonski, Erica A. Golemis, Louis M. Weiner, Igor Astsaturov
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6153–6163.
https://doi.org/10.1158/1078-0432.CCR-16-0149
Published: 15 December 2016
View article titled, Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3–MYC Interactions as a Target in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Abstract B07: Screening of patient-derived carcinoma cells and animal models identifies transcription as target in pancreatic cancer.

Vladimir Khazak, Natalia Skobeleva, Natalia Beglyarova, Egor Bobrov, Yan Zhou, Sandra A. Jablonski, Louis M. Weiner, Keren Paz, Igor Astsaturov
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): B07.
https://doi.org/10.1158/1557-3265.PDX16-B07
Published: 15 August 2016
View article titled, Abstract B07: Screening of patient-derived carcinoma cells and animal models identifies transcription as target in pancreatic cancer.
Journal Articles

Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform

Wei Guo, Xin-Rong Yang, Yun-Fan Sun, Min-Na Shen, Xiao-Lu Ma, Jiong Wu, Chun-Yan Zhang, Yan Zhou, Yang Xu, Bo Hu, Xin Zhang, Jian Zhou, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (18): 4794–4805.
https://doi.org/10.1158/1078-0432.CCR-14-0251
Published: 14 September 2014
View article titled, Clinical Significance of <em>EpCAM</em> mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform
Open the PDF for Clinical Significance of <em>EpCAM</em> mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform in another window
Includes: Supplementary data
Journal Articles

Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer

Shouyu Wang, Xuming Wu, Yansu Chen, Jianbing Zhang, Jingjing Ding, Yan Zhou, Song He, Yongfei Tan, Fulin Qiang, Jin Bai, Jinyan Zeng, Zhenghua Gong, Aiping Li, Gang Li, Oluf Dimitri Røe, Jianwei Zhou
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (10): 2987–2996.
https://doi.org/10.1158/1078-0432.CCR-11-2863
Published: 14 May 2012
View article titled, Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer
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Includes: Supplementary data
Journal Articles

EMMPRIN Expression as a Prognostic Factor in Radiotherapy of Cervical Cancer

Xing-Zhu Ju, Jin-Ming Yang, Xiao-Yan Zhou, Zi-Ting Li, Xiao-Hua Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (2): 494–501.
https://doi.org/10.1158/1078-0432.CCR-07-1072
Published: 25 January 2008
View article titled, EMMPRIN Expression as a Prognostic Factor in Radiotherapy of Cervical Cancer
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Journal Articles

Polymorphisms of MTHFD, Plasma Homocysteine Levels, and Risk of Gastric Cancer in a High-Risk Chinese Population

Lina Wang, Qiao Ke, Wensen Chen, Jianming Wang, Yongfei Tan, Yan Zhou, Zhaolai Hua, Weiliang Ding, Juying Niu, Jing Shen, Zuofeng Zhang, Xinru Wang, Yaochu Xu, Hongbing Shen
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (8): 2526–2532.
https://doi.org/10.1158/1078-0432.CCR-06-2293
Published: 16 April 2007
View article titled, Polymorphisms of MTHFD, Plasma Homocysteine Levels, and Risk of Gastric Cancer in a High-Risk Chinese Population
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