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Journal Articles

Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia

Yuting Yan, Ying Yu, Wenjie Xiong, Jun Wang, Yao Yao, Yujiao Jia, Yanshan Huang, Yuxi Li, Tingyu Wang, Rui Lyu, Hao Sun, Haoxu Wang, Qi Wang, Wei Liu, Gang An, Weiwei Sui, Yan Xu, Wenyang Huang, Zhen Yu, Dehui Zou, Mu Hao, Zhijian Xiao, Jianxiang Wang, Lugui Qiu, Shuhua Yi
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (23): 5483–5493.
https://doi.org/10.1158/1078-0432.CCR-23-3939
Published: 02 December 2024
View article titled, Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia
Open the PDF for Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia in another window
Includes: Supplementary data
Journal Articles

Identification of Therapy-Induced Clonal Evolution and Resistance Pathways in Minimal Residual Clones in Multiple Myeloma through Single-Cell Sequencing

Jian Cui, Xiaoyun Li, Shuhui Deng, Chenxing Du, Huishou Fan, Wenqiang Yan, Jingyu Xu, Xiaoqing Li, Tengteng Yu, Shuaishuai Zhang, Rui Lv, Weiwei Sui, Mu Hao, Xin Du, Yan Xu, Shuhua Yi, Dehui Zou, Tao Cheng, Lugui Qiu, Xin Gao, Gang An
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (17): 3919–3936.
https://doi.org/10.1158/1078-0432.CCR-24-0545
Published: 03 September 2024
View article titled, Identification of Therapy-Induced Clonal Evolution and Resistance Pathways in Minimal Residual Clones in Multiple Myeloma through Single-Cell Sequencing
Open the PDF for Identification of Therapy-Induced Clonal Evolution and Resistance Pathways in Minimal Residual Clones in Multiple Myeloma through Single-Cell Sequencing in another window
Includes: Supplementary data
Journal Articles

Monitoring Minimal Residual Disease in Patients with Multiple Myeloma by Targeted Tracking Serum M-Protein Using Mass Spectrometry (EasyM)

Huishou Fan, Bing Wang, Lihui Shi, Ni Pan, Wenqiang Yan, Jingyu Xu, Lixin Gong, Lingna Li, Yuntong Liu, Chenxing Du, Jian Cui, Guoqing Zhu, Shuhui Deng, Weiwei Sui, Yan Xu, Shuhua Yi, Mu Hao, Dehui Zou, Xiequn Chen, Lugui Qiu, Gang An
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (6): 1131–1142.
https://doi.org/10.1158/1078-0432.CCR-23-2767
Published: 15 March 2024
View article titled, Monitoring Minimal Residual Disease in Patients with Multiple Myeloma by Targeted Tracking Serum M-Protein Using Mass Spectrometry (EasyM)
Open the PDF for Monitoring Minimal Residual Disease in Patients with Multiple Myeloma by Targeted Tracking Serum M-Protein Using Mass Spectrometry (EasyM) in another window
Includes: Supplementary data
Journal Articles

YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer

Fan Li, Yan Xu, Bovey Liu, Pankaj Kumar Singh, Wei Zhao, Jiankang Jin, Guangchun Han, Ailing W. Scott, Xiaochuan Dong, Longfei Huo, Lang Ma, Melissa Pool Pizzi, Ying Wang, Yuan Li, Kazuto Harada, Min Xie, Heath D. Skinner, Sheng Ding, Linghua Wang, Sunil Krishnan, Randy L. Johnson, Shumei Song, Jaffer A. Ajani
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (7): 2264–2277.
https://doi.org/10.1158/1078-0432.CCR-18-1029
Published: 01 April 2019
View article titled, YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer
Open the PDF for YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer in another window
Includes: Supplementary data
Journal Articles

Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia

Na Li, Michael A. Lopez, Maria Linares, Subodh Kumar, Stefania Oliva, Joaquin Martinez-Lopez, Lian Xu, Yan Xu, Tommaso Perini, William Senapedis, Erkan Baloglu, Masood A. Shammas, Zachary Hunter, Kenneth C. Anderson, Steven P. Treon, Nikhil C. Munshi, Mariateresa Fulciniti
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 369–377.
https://doi.org/10.1158/1078-0432.CCR-18-1776
Published: 03 January 2019
View article titled, Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia
Open the PDF for Dual PAK4-NAMPT Inhibition Impacts Growth and Survival, and Increases Sensitivity to DNA-Damaging Agents in Waldenström Macroglobulinemia in another window
Includes: Supplementary data
Journal Articles

Abstract B64: The novel ZIP4 regulation and its role in cancer stem cell-related activities in ovarian cancer

Yan Xu, Qipeng Fan, Qingchun Cai, Kenneth P. Nephew
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (15_Supplement): B64.
https://doi.org/10.1158/1557-3265.OVCA17-B64
Published: 01 August 2018
View article titled, Abstract B64: The novel ZIP4 regulation and its role in cancer stem cell-related activities in ovarian cancer
Journal Articles

RNF126 as a Biomarker of a Poor Prognosis in Invasive Breast Cancer and CHEK1 Inhibitor Efficacy in Breast Cancer Cells

Xiaosong Yang, You Pan, Zhaojun Qiu, Zhanwen Du, Yao Zhang, Pengyan Fa, Shashank Gorityala, Shanhuai Ma, Shunqiang Li, Ceshi Chen, Hongbing Wang, Yan Xu, Chunhong Yan, Keri Ruth, Zhefu Ma, Junran Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (7): 1629–1643.
https://doi.org/10.1158/1078-0432.CCR-17-2242
Published: 02 April 2018
View article titled, RNF126 as a Biomarker of a Poor Prognosis in Invasive Breast Cancer and CHEK1 Inhibitor Efficacy in Breast Cancer Cells
Open the PDF for RNF126 as a Biomarker of a Poor Prognosis in Invasive Breast Cancer and CHEK1 Inhibitor Efficacy in Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Activation of the Aryl Hydrocarbon Receptor Leads to Resistance to EGFR TKIs in Non–Small Cell Lung Cancer by Activating Src-mediated Bypass Signaling

Mingxiang Ye, Yong Zhang, Hongjun Gao, Yan Xu, Pengyu Jing, Jianxiong Wu, Xinxin Zhang, Jie Xiong, Chenfang Dong, Libo Yao, Jian Zhang, Jian Zhang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (5): 1227–1239.
https://doi.org/10.1158/1078-0432.CCR-17-0396
Published: 28 February 2018
View article titled, Activation of the Aryl Hydrocarbon Receptor Leads to Resistance to EGFR TKIs in Non–Small Cell Lung Cancer by Activating Src-mediated Bypass Signaling
Open the PDF for Activation of the Aryl Hydrocarbon Receptor Leads to Resistance to EGFR TKIs in Non–Small Cell Lung Cancer by Activating Src-mediated Bypass Signaling in another window
Includes: Supplementary data
Journal Articles

Cell-Cycle and DNA-Damage Response Pathway Is Involved in Leptomeningeal Metastasis of Non–Small Cell Lung Cancer

Yun Fan, Xuehua Zhu, Yan Xu, Xuesong Lu, Yanjun Xu, Mengzhao Wang, Haiyan Xu, Jingyan Ding, Xin Ye, Luo Fang, Zhiyu Huang, Lei Gong, Hongyang Lu, Weimin Mao, Min Hu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (1): 209–216.
https://doi.org/10.1158/1078-0432.CCR-17-1582
Published: 02 January 2018
View article titled, Cell-Cycle and DNA-Damage Response Pathway Is Involved in Leptomeningeal Metastasis of Non–Small Cell Lung Cancer
Open the PDF for Cell-Cycle and DNA-Damage Response Pathway Is Involved in Leptomeningeal Metastasis of Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma

Hai-Feng Zhang, Ye Chen, Chengsheng Wu, Zhi-Yong Wu, David J. Tweardy, Abdulraheem Alshareef, Lian-Di Liao, Yu-Jie Xue, Jian-Yi Wu, Bo Chen, Xiu-E Xu, Keshav Gopal, Nidhi Gupta, En-Min Li, Li-Yan Xu, Raymond Lai
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 691–703.
https://doi.org/10.1158/1078-0432.CCR-15-1253
Published: 31 January 2016
View article titled, The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma
Open the PDF for The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

The Impact of Clone Size on the Prognostic Value of Chromosome Aberrations by Fluorescence In Situ Hybridization in Multiple Myeloma

Gang An, Zengjun Li, Yu-Tzu Tai, Chirag Acharya, Qian Li, Xiaoqi Qin, Shuhua Yi, Yan Xu, Xiaoyan Feng, Chengwen Li, Jiawei Zhao, Lihui Shi, Meirong Zang, Shuhui Deng, Weiwei Sui, Mu Hao, Dehui Zou, Yaozhong Zhao, Junyuan Qi, Tao Cheng, Kun Ru, Jianxiang Wang, Kenneth C Anderson, Lugui Qiu
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (9): 2148–2156.
https://doi.org/10.1158/1078-0432.CCR-14-2576
Published: 30 April 2015
View article titled, The Impact of Clone Size on the Prognostic Value of Chromosome Aberrations by Fluorescence <em>In Situ</em> Hybridization in Multiple Myeloma
Open the PDF for The Impact of Clone Size on the Prognostic Value of Chromosome Aberrations by Fluorescence <em>In Situ</em> Hybridization in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells

Aaron P. Rapoport, Nicole A. Aqui, Edward A. Stadtmauer, Dan T. Vogl, Yin Yan Xu, Michael Kalos, Ling Cai, Hong-Bin Fang, Brendan M. Weiss, Ashraf Badros, Saul Yanovich, Gorgun Akpek, Patricia Tsao, Alan Cross, Dean Mann, Sunita Philip, Naseem Kerr, Andrea Brennan, Zhaohui Zheng, Kathleen Ruehle, Todd Milliron, Scott E. Strome, Andres M. Salazar, Bruce L. Levine, Carl H. June
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (5): 1355–1365.
https://doi.org/10.1158/1078-0432.CCR-13-2817
Published: 02 March 2014
View article titled, Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells
Open the PDF for Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells in another window
Includes: Supplementary data
Journal Articles

The Ubiquitin–CXCR4 Axis Plays an Important Role in Acute Lung Infection–Enhanced Lung Tumor Metastasis

Libo Yan, Qingchun Cai, Yan Xu
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (17): 4706–4716.
https://doi.org/10.1158/1078-0432.CCR-13-0011
Published: 02 September 2013
View article titled, The Ubiquitin–CXCR4 Axis Plays an Important Role in Acute Lung Infection–Enhanced Lung Tumor Metastasis
Open the PDF for The Ubiquitin–CXCR4 Axis Plays an Important Role in Acute Lung Infection–Enhanced Lung Tumor Metastasis in another window
Includes: Supplementary data
Journal Articles

NGALR Is Overexpressed and Regulated by Hypomethylation in Esophageal Squamous Cell Carcinoma

Lei Cui, Li-Yan Xu, Zhong-Ying Shen, Qian Tao, Shu-Ying Gao, Zhuo Lv, Ze-Peng Du, Wang-Kai Fang, En-Min Li
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7674–7681.
https://doi.org/10.1158/1078-0432.CCR-08-0420
Published: 01 December 2008
View article titled, <em>NGALR</em> Is Overexpressed and Regulated by Hypomethylation in Esophageal Squamous Cell Carcinoma
Open the PDF for <em>NGALR</em> Is Overexpressed and Regulated by Hypomethylation in Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data