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Journal Articles

Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma

Phillip M. Galbo, Jr, Anne Tranberg Madsen, Yang Liu, Mou Peng, Yao Wei, Michael J. Ciesielski, Robert A. Fenstermaker, Sarah Graff, Cristina Montagna, Jeffrey E. Segall, Simone Sidoli, Xingxing Zang, Deyou Zheng
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 865–876.
https://doi.org/10.1158/1078-0432.CCR-23-0493
Published: 16 February 2024
View article titled, Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma
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Includes: Supplementary data
Journal Articles

Molecular Features of Cancer-associated Fibroblast Subtypes and their Implication on Cancer Pathogenesis, Prognosis, and Immunotherapy Resistance

Phillip M. Galbo, Jr, Xingxing Zang, Deyou Zheng
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2636–2647.
https://doi.org/10.1158/1078-0432.CCR-20-4226
Published: 01 May 2021
View article titled, Molecular Features of Cancer-associated Fibroblast Subtypes and their Implication on Cancer Pathogenesis, Prognosis, and Immunotherapy Resistance
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Includes: Supplementary data
Journal Articles

PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of Adult T-Cell Leukemia/Lymphoma

Elaine Y. Chung, Yun Mai, Urvi A. Shah, Yongqiang Wei, Elise Ishida, Keisuke Kataoka, Xiaoxin Ren, Kith Pradhan, Boris Bartholdy, Xiaolei Wei, Yiyu Zou, Jinghang Zhang, Seishi Ogawa, Ulrich Steidl, Xingxing Zang, Amit Verma, Murali Janakiram, B. Hilda Ye
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (12): 3589–3601.
https://doi.org/10.1158/1078-0432.CCR-18-3033
Published: 14 June 2019
View article titled, PAK Kinase Inhibition Has Therapeutic Activity in Novel Preclinical Models of Adult T-Cell Leukemia/Lymphoma
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Includes: Supplementary data
Journal Articles

Wide Expression and Significance of Alternative Immune Checkpoint Molecules, B7x and HHLA2, in PD-L1–Negative Human Lung Cancers

Haiying Cheng, Alain Borczuk, Murali Janakiram, Xiaoxin Ren, Juan Lin, Amer Assal, Balazs Halmos, Roman Perez-Soler, Xingxing Zang
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (8): 1954–1964.
https://doi.org/10.1158/1078-0432.CCR-17-2924
Published: 12 April 2018
View article titled, Wide Expression and Significance of Alternative Immune Checkpoint Molecules, B7x and HHLA2, in PD-L1–Negative Human Lung Cancers
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Journal Articles

HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status

Haiying Cheng, Murali Janakiram, Alain Borczuk, Juan Lin, Wanglong Qiu, Huijie Liu, Jordan M. Chinai, Balazs Halmos, Roman Perez-Soler, Xingxing Zang
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (3): 825–832.
https://doi.org/10.1158/1078-0432.CCR-15-3071
Published: 31 January 2017
View article titled, HHLA2, a New Immune Checkpoint Member of the B7 Family, Is Widely Expressed in Human Lung Cancer and Associated with EGFR Mutational Status
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Journal Articles

Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy

Elodie Picarda, Kim C. Ohaegbulam, Xingxing Zang
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (14): 3425–3431.
https://doi.org/10.1158/1078-0432.CCR-15-2428
Published: 14 July 2016
View article titled, Molecular Pathways: Targeting B7-H3 (CD276) for Human Cancer Immunotherapy
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Journal Articles

B7-H4(B7x)–Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients

Yu Yao, Hongxing Ye, Zengxin Qi, Lianjie Mo, Qi Yue, Aparajita Baral, Dave S.B. Hoon, Juan Carlos Vera, John D. Heiss, Clark C. Chen, Wei Hua, Jianmin Zhang, Kunlin Jin, Yin Wang, Xingxing Zang, Ying Mao, Liangfu Zhou
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (11): 2778–2790.
https://doi.org/10.1158/1078-0432.CCR-15-0858
Published: 31 May 2016
View article titled, B7-H4(B7x)–Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients
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Includes: Supplementary data
Journal Articles

Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein

Murali Janakiram, Jordan M. Chinai, Susan Fineberg, Andras Fiser, Cristina Montagna, Ramadevi Medavarapu, Ekaterina Castano, Hyungjun Jeon, Kim C. Ohaegbulam, Ruihua Zhao, Aimin Zhao, Steven C. Almo, Joseph A. Sparano, Xingxing Zang
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (10): 2359–2366.
https://doi.org/10.1158/1078-0432.CCR-14-1495
Published: 14 May 2015
View article titled, Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein
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Includes: Supplementary data
Journal Articles

The B7 Family and Cancer Therapy: Costimulation and Coinhibition

Xingxing Zang, James P. Allison
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (18): 5271–5279.
https://doi.org/10.1158/1078-0432.CCR-07-1030
Published: 17 September 2007
View article titled, The B7 Family and Cancer Therapy: Costimulation and Coinhibition
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