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Journal Articles

An Open-label, Multicenter, Single-arm, Phase II Study of Fluzoparib in Patients with Germline BRCA1/2 Mutation and Platinum-sensitive Recurrent Ovarian Cancer

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Ning Li, Hualei Bu, Jihong Liu, Jianqing Zhu, Qi Zhou, Li Wang, Rutie Yin, Xiaohua Wu, Shuzhong Yao, Kangsheng Gu, Hui Zhang, Guiling Li, Hongming Pan, Qiang Wu, Ruifang An, Xinfeng Yang, Yaping Zhu, Xiaoping Wan, Wei Duan, Jianping Xiong, Hongyan Guo, Ge Lou, Jing Wang, Wenjing Hu, Xin Zhang, Yuanguang Meng, Ben Zhang, Yuting Wang, Quanren Wang, Lingying Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2452–2458.
https://doi.org/10.1158/1078-0432.CCR-20-3546
Published: 01 May 2021
View articletitled, An Open-label, Multicenter, Single-arm, Phase II Study of Fluzoparib in Patients with Germline BRCA1/2 Mutation and Platinum-sensitive Recurrent Ovarian Cancer
Open the PDF for An Open-label, Multicenter, Single-arm, Phase II Study of Fluzoparib in Patients with Germline BRCA1/2 Mutation and Platinum-sensitive Recurrent Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PO044: A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer

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Sarah E. Paraghamian, Gabrielle M. Hawkins, Wenchuan Sun, Yali Fan, Xin Zhang, Hongyan Suo, Varun Vijay Prabhu, Joshua E. Allen, Chunxiao Zhou, Victoria Bae-Jump
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3_Supplement): PO044.
https://doi.org/10.1158/1557-3265.ENDOMET20-PO044
Published: 01 February 2021
View articletitled, Abstract PO044: A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer
Journal Articles

Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling

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Jianxiong Ji, Ran Xu, Kaikai Ding, Guoqing Bao, Xin Zhang, Bin Huang, Xinyu Wang, Aurora Martinez, Xiuying Wang, Gang Li, Hrvoje Miletic, Frits Thorsen, Rolf Bjerkvig, Lei Xiang, Bo Han, Anjing Chen, Xingang Li, Jian Wang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (22): 6868–6881.
https://doi.org/10.1158/1078-0432.CCR-19-0747
Published: 15 November 2019
View articletitled, Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling
Open the PDF for Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB Signaling in another window
Includes: Supplementary data
Journal Articles

Genome-wide RNAi Screening Identifies RFC4 as a Factor That Mediates Radioresistance in Colorectal Cancer by Facilitating Nonhomologous End Joining Repair

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Xue-Cen Wang, Xin Yue, Rong-Xin Zhang, Ting-Yu Liu, Zhi-Zhong Pan, Meng-Jie Yang, Zhen-Hai Lu, Zi-Yang Wang, Jian-Hong Peng, Li-Yuan Le, Gao-Yuan Wang, Qi-Hua Peng, Yuan Meng, Wenlin Huang, Ran-Yi Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4567–4579.
https://doi.org/10.1158/1078-0432.CCR-18-3735
Published: 15 July 2019
View articletitled, Genome-wide RNAi Screening Identifies RFC4 as a Factor That Mediates Radioresistance in Colorectal Cancer by Facilitating Nonhomologous End Joining Repair
Open the PDF for Genome-wide RNAi Screening Identifies RFC4 as a Factor That Mediates Radioresistance in Colorectal Cancer by Facilitating Nonhomologous End Joining Repair in another window
Includes: Supplementary data
Journal Articles

Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis

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Li-Peng Hu, Xiao-Xin Zhang, Shu-Heng Jiang, Ling-Ye Tao, Qing Li, Li-Li Zhu, Ming-Wei Yang, Yan-Miao Huo, Yong-Sheng Jiang, Guang-Ang Tian, Xiao-Yan Cao, Yan-Li Zhang, Qin Yang, Xiao-Mei Yang, Ya-Hui Wang, Jun Li, Gary Guishan Xiao, Yong-Wei Sun, Zhi-Gang Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1318–1330.
https://doi.org/10.1158/1078-0432.CCR-18-2297
Published: 15 February 2019
View articletitled, Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis
Open the PDF for Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis in another window
Includes: Supplementary data
Journal Articles

The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes

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Matthew P. Salomon, Xiaowen Wang, Diego M. Marzese, Sandy C. Hsu, Nellie Nelson, Xin Zhang, Chikako Matsuba, Yuki Takasumi, Carmen Ballesteros-Merino, Bernard A. Fox, Garni Barkhoudarian, Daniel F. Kelly, Dave S.B. Hoon
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (17): 4126–4136.
https://doi.org/10.1158/1078-0432.CCR-17-2206
Published: 04 September 2018
View articletitled, The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes
Open the PDF for The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes in another window
Includes: Supplementary data
Journal Articles

Adjuvant Transarterial Chemoembolization for HBV-Related Hepatocellular Carcinoma After Resection: A Randomized Controlled Study

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Zheng Wang, Zhenggang Ren, Yi Chen, Jie Hu, Guohuan Yang, Lei Yu, Xinrong Yang, Ao Huang, Xin Zhang, Shaolai Zhou, Huichuan Sun, Yanhong Wang, Ningling Ge, Xiaoyu Xu, Zhaoyou Tang, Wanyee Lau, Jia Fan, Jiping Wang, Jian Zhou
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (9): 2074–2081.
https://doi.org/10.1158/1078-0432.CCR-17-2899
Published: 30 April 2018
View articletitled, Adjuvant Transarterial Chemoembolization for HBV-Related Hepatocellular Carcinoma After Resection: A Randomized Controlled Study
Open the PDF for Adjuvant Transarterial Chemoembolization for HBV-Related Hepatocellular Carcinoma After Resection: A Randomized Controlled Study in another window
Includes: Supplementary data
Journal Articles

Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma

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Wei Guo, Yun-Fan Sun, Min-Na Shen, Xiao-Lu Ma, Jiong Wu, Chun-Yan Zhang, Yan Zhou, Yang Xu, Bo Hu, Min Zhang, Gang Wang, Wei-Qin Chen, Lin Guo, Ren-Quan Lu, Chao-Hui Zhou, Xin Zhang, Ying-Hong Shi, Shuang-jian Qiu, Bai-shen Pan, Ya Cao, Jian Zhou, Xin-Rong Yang, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (9): 2203–2213.
https://doi.org/10.1158/1078-0432.CCR-17-1753
Published: 30 April 2018
View articletitled, Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma
Open the PDF for Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma

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Yun-Fan Sun, Wei Guo, Yang Xu, Yin-Hong Shi, Zi-Jun Gong, Yuan Ji, Min Du, Xin Zhang, Bo Hu, Ao Huang, George G. Chen, Paul B.S. Lai, Ya Cao, Shuang-Jian Qiu, Jian Zhou, Xin-Rong Yang, Jia Fan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (3): 547–559.
https://doi.org/10.1158/1078-0432.CCR-17-1063
Published: 31 January 2018
View articletitled, Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma
Open the PDF for Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract A11: Using a patient-derived orthotopic xenograft (PDOX) model to screen drugs targeting renal cell carcinoma (RCC) metastasis: A personalized therapeutic strategy

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Jessie Gills, Ravan Moret, Xin Zhang, Ashley Richman, John Nelson, Grace Maresh, Christudas Morais, Glenda Gobe, Sunil Talwar, Marc Matrana, Stephen Bardot, Li Li
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): A11.
https://doi.org/10.1158/1557-3265.PDX16-A11
Published: 15 August 2016
View articletitled, Abstract A11: Using a patient-derived orthotopic xenograft (PDOX) model to screen drugs targeting renal cell carcinoma (RCC) metastasis: A personalized therapeutic strategy
Journal Articles

Direct Serum Assay for Cell-Free Bmi-1 mRNA and Its Potential Diagnostic and Prognostic Value for Colorectal Cancer

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Xin Zhang, Xiaoyun Yang, Yanli Zhang, Xinfeng Liu, Guixi Zheng, Yongmei Yang, Lili Wang, Lutao Du, Chuanxin Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (5): 1225–1233.
https://doi.org/10.1158/1078-0432.CCR-14-1761
Published: 01 March 2015
View articletitled, Direct Serum Assay for Cell-Free Bmi-1 mRNA and Its Potential Diagnostic and Prognostic Value for Colorectal Cancer
Open the PDF for Direct Serum Assay for Cell-Free Bmi-1 mRNA and Its Potential Diagnostic and Prognostic Value for Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma

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Bo Hu, Xin-Rong Yang, Yang Xu, Yun-Fan Sun, Chao Sun, Wei Guo, Xin Zhang, Wei-Min Wang, Shuang-Jian Qiu, Jian Zhou, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (23): 6212–6222.
https://doi.org/10.1158/1078-0432.CCR-14-0442
Published: 30 November 2014
View articletitled, Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma
Open the PDF for Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform

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Wei Guo, Xin-Rong Yang, Yun-Fan Sun, Min-Na Shen, Xiao-Lu Ma, Jiong Wu, Chun-Yan Zhang, Yan Zhou, Yang Xu, Bo Hu, Xin Zhang, Jian Zhou, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (18): 4794–4805.
https://doi.org/10.1158/1078-0432.CCR-14-0251
Published: 14 September 2014
View articletitled, Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform
Open the PDF for Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform in another window
Includes: Supplementary data
Journal Articles

Enhancement of Docetaxel-Induced Cytotoxicity by Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 Pathways in Squamous Cell Carcinoma of the Head and Neck

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Mi Sun Choe, Zhuo Chen, Carmen M. Klass, Xin Zhang, Dong M. Shin
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (10): 3015–3023.
https://doi.org/10.1158/1078-0432.CCR-06-2959
Published: 15 May 2007
View articletitled, Enhancement of Docetaxel-Induced Cytotoxicity by Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 Pathways in Squamous Cell Carcinoma of the Head and Neck
Open the PDF for Enhancement of Docetaxel-Induced Cytotoxicity by Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 Pathways in Squamous Cell Carcinoma of the Head and Neck in another window
Journal Articles

Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model

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Xin Zhang, Zhuo (Georgia) Chen, Mi Sun Choe, Yan Lin, Shi-Yong Sun, H. Samuel Wieand, Hyung Ju C. Shin, Amy Chen, Fadlo R. Khuri, Dong M. Shin
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6261–6269.
https://doi.org/10.1158/1078-0432.CCR-04-2102
Published: 06 September 2005
View articletitled, Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model
Open the PDF for Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model in another window
Journal Articles

Correlation of Protease-Activated Receptor-1 With Differentiation Markers in Squamous Cell Carcinoma of the Head and Neck and Its Implication in Lymph Node Metastasis

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Xin Zhang, Jennifer L. Hunt, Doug P. Landsittel, Susan Muller, Karen Adler-Storthz, Robert L. Ferris, Dong M. Shin, Zhuo (Georgia) Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (24): 8451–8459.
https://doi.org/10.1158/1078-0432.CCR-04-0546
Published: 28 December 2004
View articletitled, Correlation of Protease-Activated Receptor-1 With Differentiation Markers in Squamous Cell Carcinoma of the Head and Neck and Its Implication in Lymph Node Metastasis
Open the PDF for Correlation of Protease-Activated Receptor-1 With Differentiation Markers in Squamous Cell Carcinoma of the Head and Neck and Its Implication in Lymph Node Metastasis in another window
Journal Articles

Simultaneously Targeting Epidermal Growth Factor Receptor Tyrosine Kinase and Cyclooxygenase-2, an Efficient Approach to Inhibition of Squamous Cell Carcinoma of the Head and Neck

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Zhuo (Georgia) Chen, Xin Zhang, Mengfeng Li, Zhiqiang Wang, H. Samuel Wieand, Jennifer R. Grandis, Dong M. Shin
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (17): 5930–5939.
https://doi.org/10.1158/1078-0432.CCR-03-0677
Published: 08 September 2004
View articletitled, Simultaneously Targeting Epidermal Growth Factor Receptor Tyrosine Kinase and Cyclooxygenase-2, an Efficient Approach to Inhibition of Squamous Cell Carcinoma of the Head and Neck
Open the PDF for Simultaneously Targeting Epidermal Growth Factor Receptor Tyrosine Kinase and Cyclooxygenase-2, an Efficient Approach to Inhibition of Squamous Cell Carcinoma of the Head and Neck in another window
Journal Articles

Purging of Contaminating Breast Cancer Cells from Hematopoietic Stem Cell Grafts by Adenoviral GAL-TEK Gene Therapy and Magnetic Antibody Cell Separation

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Frank C. Marini, Virginia Snell, Qingnan Yu, Xin Zhang, S. Eva Singletary, Richard Champlin, Michael Andreeff
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (6): 1557–1568.
Published: 01 June 1999
View articletitled, Purging of Contaminating Breast Cancer Cells from Hematopoietic Stem Cell Grafts by Adenoviral GAL-TEK Gene Therapy and Magnetic Antibody Cell Separation
Open the PDF for Purging of Contaminating Breast Cancer Cells from Hematopoietic Stem Cell Grafts by Adenoviral GAL-TEK Gene Therapy and Magnetic Antibody Cell Separation in another window