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Journal Articles

A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response–Dependent Survival of Quiescent Cancer Cells

Veronica Calvo, Wei Zheng, Anna Adam-Artigues, Kirk A. Staschke, Xin Huang, Julie F. Cheung, Ana Rita Nobre, Sho Fujisawa, David Liu, Maria Fumagalli, David Surguladze, Michael E. Stokes, Ari Nowacek, Mark Mulvihill, Eduardo F. Farias, Julio A. Aguirre-Ghiso
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF18.
https://doi.org/10.1158/1078-0432.CCR-23-1427
Published: 20 November 2023
View article titled, A PERK-Specific Inhibitor Blocks Metastatic Progression by Limiting Integrated Stress Response–Dependent Survival of Quiescent Cancer Cells
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Includes: Supplementary data
Journal Articles

Overall Survival with Palbociclib and Fulvestrant in Women with HR+/HER2− ABC: Updated Exploratory Analyses of PALOMA-3, a Double-blind, Phase III Randomized Study

Massimo Cristofanilli, Hope S. Rugo, Seock-Ah Im, Dennis J. Slamon, Nadia Harbeck, Igor Bondarenko, Norikazu Masuda, Marco Colleoni, Angela DeMichele, Sherene Loi, Hiroji Iwata, Ben O'Leary, Fabrice André, Sibylle Loibl, Eustratios Bananis, Yuan Liu, Xin Huang, Sindy Kim, Maria Jose Lechuga Frean, Nicholas C. Turner
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (16): 3433–3442.
https://doi.org/10.1158/1078-0432.CCR-22-0305
Published: 15 August 2022
View article titled, Overall Survival with Palbociclib and Fulvestrant in Women with HR<sup>+</sup>/HER2<sup>−</sup> ABC: Updated Exploratory Analyses of PALOMA-3, a Double-blind, Phase III Randomized Study
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Includes: Supplementary data
Journal Articles

First-in-Human Dose-Escalation Study of Cyclin-Dependent Kinase 9 Inhibitor VIP152 in Patients with Advanced Malignancies Shows Early Signs of Clinical Efficacy

Jennifer R. Diamond, Valentina Boni, Emerson Lim, Grzegorz Nowakowski, Raul Cordoba, Daniel Morillo, Ray Valencia, Isabelle Genvresse, Claudia Merz, Oliver Boix, Melanie M. Frigault, Joy M. Greer, Ahmed M. Hamdy, Xin Huang, Raquel Izumi, Harvey Wong, Victor Moreno
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (7): 1285–1293.
https://doi.org/10.1158/1078-0432.CCR-21-3617
Published: 01 April 2022
View article titled, First-in-Human Dose-Escalation Study of Cyclin-Dependent Kinase 9 Inhibitor VIP152 in Patients with Advanced Malignancies Shows Early Signs of Clinical Efficacy
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Includes: Supplementary data
Journal Articles

Cross-Site Concordance Evaluation of Tumor DNA and RNA Sequencing Platforms for the CIMAC-CIDC Network

Zexian Zeng, Jingxin Fu, Carrie Cibulskis, Aashna Jhaveri, Curtis Gumbs, Biswajit Das, Beatriz Sanchez-Espiridion, Sylvie Janssens, Len Taing, Jin Wang, James Lindsay, Tomas Vilimas, Jianhua Zhang, Collin Tokheim, Avinash Sahu, Peng Jiang, Chunhua Yan, Dzifa Yawa Duose, Ethan Cerami, Li Chen, David Cohen, Qingrong Chen, Rebecca Enos, Xin Huang, Jack J. Lee, Yang Liu, Donna S. Neuberg, Cu Nguyen, Candace Patterson, Sharmistha Sarkar, Sachet Shukla, Ming Tang, Junko Tsuji, Mohamed Uduman, Xiaoman Wang, Jason L. Weirather, Jijun Yu, Joyce Yu, Jianjun Zhang, Jiexin Zhang, Daoud Meerzaman, Magdalena Thurin, Andrew Futreal, Chris Karlovich, Stacey B. Gabriel, Ignacio Ivan Wistuba, X. Shirley Liu, Catherine J. Wu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (18): 5049–5061.
https://doi.org/10.1158/1078-0432.CCR-20-3251
Published: 15 September 2021
View article titled, Cross-Site Concordance Evaluation of Tumor DNA and RNA Sequencing Platforms for the CIMAC-CIDC Network
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Includes: Supplementary data
Journal Articles

Intracranial Efficacy of Selpercatinib in RET Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial

Vivek Subbiah, Justin F. Gainor, Geoffrey R. Oxnard, Daniel S.W. Tan, Dwight H. Owen, Byoung Chul Cho, Herbert H. Loong, Caroline E. McCoach, Jared Weiss, Yu Jung Kim, Lyudmila Bazhenova, Keunchil Park, Haruko Daga, Benjamin Besse, Oliver Gautschi, Christian Rolfo, Edward Y. Zhu, Jennifer F. Kherani, Xin Huang, Suhyun Kang, Alexander Drilon
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (15): 4160–4167.
https://doi.org/10.1158/1078-0432.CCR-21-0800
Published: 01 August 2021
View article titled, Intracranial Efficacy of Selpercatinib in <em>RET</em> Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial
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Includes: Supplementary data
Journal Articles

Complement Pathway Is Frequently Altered in Endometriosis and Endometriosis-Associated Ovarian Cancer

Swati Suryawanshi, Xin Huang, Esther Elishaev, Raluca A. Budiu, Lixin Zhang, SungHwan Kim, Nicole Donnellan, Gina Mantia-Smaldone, Tianzhou Ma, George Tseng, Ted Lee, Suketu Mansuria, Robert P. Edwards, Anda M. Vlad
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (23): 6163–6174.
https://doi.org/10.1158/1078-0432.CCR-14-1338
Published: 30 November 2014
View article titled, Complement Pathway Is Frequently Altered in Endometriosis and Endometriosis-Associated Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Correlation of KIT and PDGFRA mutation status with sunitinib activity in imatinib-resistant GIST

Michael C. Heinrich, Robert G. Maki, Christopher L. Corless, Cristina R. Antonescu, Jonathan A. Fletcher, Christopher D. Fletcher, Xin Huang, Charles M. Baum, George D. Demetri
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19_Supplement): B56.
Published: 15 August 2014
View article titled, Correlation of <em>KIT</em> and <em>PDGFRA</em> mutation status with sunitinib activity in imatinib-resistant GIST
Journal Articles

Abstract A75: miR-200 family in endometriosis-associated ovarian cancer

Swati Suryawanshi, Anda Vlad, Robert Edwards, Raluca Budiu, Xin Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (19_Supplement): A75.
https://doi.org/10.1158/1078-0432.OVCA13-A75
Published: 13 May 2014
View article titled, Abstract A75: miR-200 family in endometriosis-associated ovarian cancer
Journal Articles

Abstract B71: Immune mechanisms that drive early carcinogenesis in endometriosis-associated ovarian cancer

Swati Suryawanshi, Xin Huang, Raluca Budiu, Gina Mantia, Robert Edwards, Anda Vlad
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (19_Supplement): B71.
https://doi.org/10.1158/1078-0432.OVCA13-B71
Published: 13 May 2014
View article titled, Abstract B71: Immune mechanisms that drive early carcinogenesis in endometriosis-associated ovarian cancer
Journal Articles

Plasma MicroRNAs in Ovarian Cancer—Response

Xin Huang, Anda M. Vlad
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (12): 3326.
https://doi.org/10.1158/1078-0432.CCR-13-1022
Published: 13 June 2013
View article titled, Plasma MicroRNAs in Ovarian Cancer—Response
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Journal Articles

Plasma MicroRNAs as Novel Biomarkers for Endometriosis and Endometriosis-Associated Ovarian Cancer

Swati Suryawanshi, Anda M. Vlad, Hui-Min Lin, Gina Mantia-Smaldone, Robin Laskey, MinJae Lee, Yan Lin, Nicole Donnellan, Marcia Klein-Patel, Ted Lee, Suketu Mansuria, Esther Elishaev, Raluca Budiu, Robert P. Edwards, Xin Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (5): 1213–1224.
https://doi.org/10.1158/1078-0432.CCR-12-2726
Published: 03 March 2013
View article titled, Plasma MicroRNAs as Novel Biomarkers for Endometriosis and Endometriosis-Associated Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Complete Longitudinal Analyses of the Randomized, Placebo-Controlled, Phase III Trial of Sunitinib in Patients with Gastrointestinal Stromal Tumor following Imatinib Failure

George D. Demetri, Christopher R. Garrett, Patrick Schöffski, Manisha H. Shah, Jaap Verweij, Serge Leyvraz, Herbert I. Hurwitz, Antonio Lopez Pousa, Axel Le Cesne, David Goldstein, Luis Paz-Ares, Jean-Yves Blay, Grant A. McArthur, Qiang (Casey) Xu, Xin Huang, Charles S. Harmon, Vanessa Tassell, Darrel P. Cohen, Paolo G. Casali
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (11): 3170–3179.
https://doi.org/10.1158/1078-0432.CCR-11-3005
Published: 31 May 2012
View article titled, Complete Longitudinal Analyses of the Randomized, Placebo-Controlled, Phase III Trial of Sunitinib in Patients with Gastrointestinal Stromal Tumor following Imatinib Failure
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Includes: Supplementary data
Journal Articles

Analyzing the Pivotal Trial That Compared Sunitinib and IFN-α in Renal Cell Carcinoma, Using a Method That Assesses Tumor Regression and Growth

Wilfred D. Stein, Julia Wilkerson, Sindy T. Kim, Xin Huang, Robert J. Motzer, Antonio Tito Fojo, Susan E. Bates
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (8): 2374–2381.
https://doi.org/10.1158/1078-0432.CCR-11-2275
Published: 16 April 2012
View article titled, Analyzing the Pivotal Trial That Compared Sunitinib and IFN-α in Renal Cell Carcinoma, Using a Method That Assesses Tumor Regression and Growth
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Includes: Supplementary data
Journal Articles

Electrocardiographic Characterization of the QTc Interval in Patients with Advanced Solid Tumors: Pharmacokinetic- Pharmacodynamic Evaluation of Sunitinib

Carlo L. Bello, Marilyn Mulay, Xin Huang, Shem Patyna, Melissa Dinolfo, Steven Levine, Andrew Van Vugt, Melvin Toh, Charles Baum, Lee Rosen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 7045–7052.
https://doi.org/10.1158/1078-0432.CCR-09-1521
Published: 11 November 2009
View article titled, Electrocardiographic Characterization of the QTc Interval in Patients with Advanced Solid Tumors: Pharmacokinetic- Pharmacodynamic Evaluation of Sunitinib
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Journal Articles

Molecular Target Modulation, Imaging, and Clinical Evaluation of Gastrointestinal Stromal Tumor Patients Treated with Sunitinib Malate after Imatinib Failure

George D. Demetri, Michael C. Heinrich, Jonathan A. Fletcher, Christopher D.M. Fletcher, Annick D. Van den Abbeele, Christopher L. Corless, Cristina R. Antonescu, Suzanne George, Jeffrey A. Morgan, Ming Hui Chen, Carlo L. Bello, Xin Huang, Darrel P. Cohen, Charles M. Baum, Robert G. Maki
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5902–5909.
https://doi.org/10.1158/1078-0432.CCR-09-0482
Published: 14 September 2009
View article titled, Molecular Target Modulation, Imaging, and Clinical Evaluation of Gastrointestinal Stromal Tumor Patients Treated with Sunitinib Malate after Imatinib Failure
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Includes: Supplementary data
Journal Articles

Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure

Samuel E. DePrimo, Xin Huang, Martin E. Blackstein, Christopher R. Garrett, Charles S. Harmon, Patrick Schöffski, Manisha H. Shah, Jaap Verweij, Charles M. Baum, George D. Demetri
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5869–5877.
https://doi.org/10.1158/1078-0432.CCR-08-2480
Published: 14 September 2009
View article titled, Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure
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Includes: Supplementary data
Journal Articles

Phase I Clinical and Pharmacodynamic Evaluation of Oral CI-1033 in Patients with Refractory Cancer

Ralph G. Zinner, John Nemunaitis, Irene Eiseman, Hyung Ju C. Shin, Stephen C. Olson, James Christensen, Xin Huang, Peter F. Lenehan, Nicholas J. Donato, Dong M. Shin
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (10): 3006–3014.
https://doi.org/10.1158/1078-0432.CCR-06-1958
Published: 15 May 2007
View article titled, Phase I Clinical and Pharmacodynamic Evaluation of Oral CI-1033 in Patients with Refractory Cancer
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Journal Articles

Hepatocyte Growth Factor Promotes Cancer Cell Migration and Angiogenic Factors Expression: A Prognostic Marker of Human Esophageal Squamous Cell Carcinomas

Yi Ren, Brian Cao, Simon Law, Yi Xie, Ping Yin Lee, Leo Cheung, Yongxong Chen, Xin Huang, Hiu Man Chan, Ping Zhao, John Luk, George Vande Woude, John Wong
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (17): 6190–6197.
https://doi.org/10.1158/1078-0432.CCR-04-2553
Published: 06 September 2005
View article titled, Hepatocyte Growth Factor Promotes Cancer Cell Migration and Angiogenic Factors Expression: A Prognostic Marker of Human Esophageal Squamous Cell Carcinomas
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Journal Articles

Prediction of Lymph Node Metastasis by Analysis of Gene Expression Profiles in Primary Lung Adenocarcinomas

Liqiang Xi, James Lyons-Weiler, Michael C. Coello, Xin Huang, William E. Gooding, James D. Luketich, Tony E. Godfrey
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (11): 4128–4135.
https://doi.org/10.1158/1078-0432.CCR-04-2525
Published: 01 June 2005
View article titled, Prediction of Lymph Node Metastasis by Analysis of Gene Expression Profiles in Primary Lung Adenocarcinomas
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