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Xiayu Rao
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Journal Articles

COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Antje Lindemann, Ameeta A. Patel, Natalie L. Silver, Lin Tang, Zhiyi Liu, Li Wang, Noriaki Tanaka, Xiayu Rao, Hideaki Takahashi, Nakachi K. Maduka, Mei Zhao, Tseng-Cheng Chen, WeiWei Liu, Meng Gao, Jing Wang, Steven J. Frank, Walter N. Hittelman, Gordon B. Mills, Jeffrey N. Myers, Abdullah A. Osman
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (18): 5650–5662.
https://doi.org/10.1158/1078-0432.CCR-19-0096
Published: 13 September 2019
View article titled, COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms
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Includes: Multimedia, Supplementary data
Journal Articles

Combined Inhibition of STAT3 and DNA Repair in Palbociclib-Resistant ER-Positive Breast Cancer

Nicole M. Kettner, Smruthi Vijayaraghavan, Merih Guray Durak, Tuyen Bui, Mehrnoosh Kohansal, Min Jin Ha, Bin Liu, Xiayu Rao, Jing Wang, Min Yi, Jason P.W. Carey, Xian Chen, T. Kris Eckols, Akshara S. Raghavendra, Nuhad K. Ibrahim, Meghan Sri Karuturi, Stephanie S. Watowich, Aysegul Sahin, David J. Tweardy, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 3996–4013.
https://doi.org/10.1158/1078-0432.CCR-18-3274
Published: 01 July 2019
View article titled, Combined Inhibition of STAT3 and DNA Repair in Palbociclib-Resistant ER-Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

PDK1 Mediates NOTCH1-Mutated Head and Neck Squamous Carcinoma Vulnerability to Therapeutic PI3K/mTOR Inhibition

Vaishnavi Sambandam, Mitchell J. Frederick, Li Shen, Pan Tong, Xiayu Rao, Shaohua Peng, Ratnakar Singh, Tuhina Mazumdar, Chenfei Huang, Qiuli Li, Curtis R. Pickering, Jeffery N. Myers, Jing Wang, Faye M. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (11): 3329–3340.
https://doi.org/10.1158/1078-0432.CCR-18-3276
Published: 03 June 2019
View article titled, PDK1 Mediates <em>NOTCH1</em>-Mutated Head and Neck Squamous Carcinoma Vulnerability to Therapeutic PI3K/mTOR Inhibition
Open the PDF for PDK1 Mediates <em>NOTCH1</em>-Mutated Head and Neck Squamous Carcinoma Vulnerability to Therapeutic PI3K/mTOR Inhibition in another window
Includes: Supplementary data
Journal Articles

High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma

Vlad C. Sandulache, Chieko Michikawa, Pranav Kataria, Frederico O. Gleber-Netto, Diana Bell, Sanchit Trivedi, Xiayu Rao, Jing Wang, Mei Zhao, Samar Jasser, Jeffrey N. Myers, Curtis R. Pickering
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (7): 1727–1733.
https://doi.org/10.1158/1078-0432.CCR-17-0721
Published: 02 April 2018
View article titled, High-Risk <em>TP53</em> Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation

Noriaki Tanaka, Ameeta A. Patel, Lin Tang, Natalie L. Silver, Antje Lindemann, Hideaki Takahashi, Roman Jaksik, Xiayu Rao, Nene N. Kalu, Tseng-Cheng Chen, Jiping Wang, Mitchell J. Frederick, Faye Johnson, Frederico O. Gleber-Netto, Siqing Fu, Marek Kimmel, Jing Wang, Walter N. Hittelman, Curtis R. Pickering, Jeffrey N. Myers, Abdullah A. Osman
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (21): 6541–6554.
https://doi.org/10.1158/1078-0432.CCR-17-0947
Published: 31 October 2017
View article titled, Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk <em>TP53</em> Mutation
Open the PDF for Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk <em>TP53</em> Mutation in another window
Includes: Multimedia, Supplementary data