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Journal Articles

CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression

Jordan L. Kohlmeyer, Joshua J. Lingo, Courtney A. Kaemmer, Amanda Scherer, Akshaya Warrier, Ellen Voigt, Juan A. Raygoza Garay, Gavin R. McGivney, Qierra R. Brockman, Amy Tang, Ana Calizo, Kai Pollard, Xiaochun Zhang, Angela C. Hirbe, Christine A. Pratilas, Mariah Leidinger, Patrick Breheny, Michael S. Chimenti, Jessica C. Sieren, Varun Monga, Munir R. Tanas, David K. Meyerholz, Benjamin W. Darbro, Rebecca D. Dodd, Dawn E. Quelle
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (17): 3484–3497.
https://doi.org/10.1158/1078-0432.CCR-23-0749
Published: 01 September 2023
View article titled, CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression
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Includes: Supplementary data
Journal Articles

MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors

Dana C. Borcherding, Neha V. Amin, Kevin He, Xiaochun Zhang, Yang Lyu, Carina Dehner, Himanshi Bhatia, Angad Gothra, Layla Daud, Peter Ruminski, Christine A. Pratilas, Kai Pollard, Taylor Sundby, Brigitte C. Widemann, Angela C. Hirbe
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (8): 1592–1604.
https://doi.org/10.1158/1078-0432.CCR-22-3722
Published: 14 April 2023
View article titled, MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors
Open the PDF for MEK Inhibition Synergizes with TYK2 Inhibitors in NF1-Associated Malignant Peripheral Nerve Sheath Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract B006: Development of a NF1-MPNST-PDX liquid biopsy model using whole-genome sequencing and quantitative PCR of mouse-derived cell-free DNA

Paul A. Jones, Wenjia Feng, Xiaochun Zhang, Peter K. Harris, Taylor Sundby, Jeffrey J. Szymanski, Divya Srihari, Faridi Qaium, Jack F. Shern, Aadel A. Chaudhuri, Angela C. Hirbe
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18_Supplement): B006.
https://doi.org/10.1158/1557-3265.SARCOMAS22-B006
Published: 15 September 2022
View article titled, Abstract B006: Development of a NF1-MPNST-PDX liquid biopsy model using whole-genome sequencing and quantitative PCR of mouse-derived cell-free DNA
Journal Articles

Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma

Angela C. Hirbe, Sonika Dahiya, Christopher A. Miller, Tiandao Li, Robert S. Fulton, Xiaochun Zhang, Sandra McDonald, Katherine DeSchryver, Eric J. Duncavage, Jessica Walrath, Karlyne M. Reilly, Haley J. Abel, Melike Pekmezci, Arie Perry, Timothy J. Ley, David H. Gutmann
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (18): 4201–4211.
https://doi.org/10.1158/1078-0432.CCR-14-3049
Published: 14 September 2015
View article titled, Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma
Open the PDF for Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform Neurofibroma in another window
Includes: Supplementary data
Journal Articles

Treatment of Radioresistant Stem-Like Esophageal Cancer Cells by an Apoptotic Gene-Armed, Telomerase-Specific Oncolytic Adenovirus

Xiaochun Zhang, Ritsuko Komaki, Li Wang, Bingliang Fang, Joe Y. Chang
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2813–2823.
https://doi.org/10.1158/1078-0432.CCR-07-1528
Published: 01 May 2008
View article titled, Treatment of Radioresistant Stem-Like Esophageal Cancer Cells by an Apoptotic Gene-Armed, Telomerase-Specific Oncolytic Adenovirus
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Journal Articles

Radiotherapy Sensitization by Tumor-Specific TRAIL Gene Targeting Improves Survival of Mice Bearing Human Non–Small Cell Lung Cancer

Xiaochun Zhang, Rex Min Cheung, Ritsuko Komaki, Bingliang Fang, Joe Y. Chang
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (18): 6657–6668.
https://doi.org/10.1158/1078-0432.CCR-04-2699
Published: 15 September 2005
View article titled, Radiotherapy Sensitization by Tumor-Specific <em>TRAIL</em> Gene Targeting Improves Survival of Mice Bearing Human Non–Small Cell Lung Cancer
Open the PDF for Radiotherapy Sensitization by Tumor-Specific <em>TRAIL</em> Gene Targeting Improves Survival of Mice Bearing Human Non–Small Cell Lung Cancer in another window