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Journal Articles

Abstract A056: Performance of multi-biomarker class reflex testing in a prospectively-collected cohort

Vladimir Gainullin, Jin Bae, Violeta Beleva Guthrie, Fanglei Zhuang, Chen Ji, Christopher Tyson, Mark Evans, Kevin Arvai, Melissa Gray, Madhav Kumar, Mael Manesse, Xi Chen, Philip Uren, Gustavo C. Cerqueira, Amin Mazloom, Jorge Garces, Tomasz M. Beer, Frank Diehl
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): A056.
https://doi.org/10.1158/1557-3265.LIQBIOP24-A056
Published: 13 November 2024
View article titled, Abstract A056: Performance of multi-biomarker class reflex testing in a prospectively-collected cohort
Journal Articles

Germline USP36 Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non–Small Cell Lung Cancer

Shaoxing Guan, Xi Chen, Yuru Wei, Fei Wang, Wen Xie, Youhao Chen, Heng Liang, Xia Zhu, Yunpeng Yang, Wenfeng Fang, Yan Huang, Hongyun Zhao, Xiaoxu Zhang, Shu Liu, Wei Zhuang, Min Huang, Xueding Wang, Li Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (7): 1382–1396.
https://doi.org/10.1158/1078-0432.CCR-23-2357
Published: 01 April 2024
View article titled, Germline <em>USP36</em> Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non–Small Cell Lung Cancer
Open the PDF for Germline <em>USP36</em> Mutation Confers Resistance to EGFR-TKIs by Upregulating MLLT3 Expression in Patients with Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

FOXM1 Variant Contributes to Gefitinib Resistance via Activating Wnt/β-Catenin Signal Pathway in Patients with Non–Small Cell Lung Cancer

Shaoxing Guan, Xi Chen, Youhao Chen, Wen Xie, Heng Liang, Xia Zhu, Yunpeng Yang, Wenfeng Fang, Yan Huang, Hongyun Zhao, Wei Zhuang, Shu Liu, Min Huang, Xueding Wang, Li Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3770–3784.
https://doi.org/10.1158/1078-0432.CCR-22-0791
Published: 01 September 2022
View article titled, <em>FOXM1</em> Variant Contributes to Gefitinib Resistance via Activating Wnt/β-Catenin Signal Pathway in Patients with Non–Small Cell Lung Cancer
Open the PDF for <em>FOXM1</em> Variant Contributes to Gefitinib Resistance via Activating Wnt/β-Catenin Signal Pathway in Patients with Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Camrelizumab in Combination with Apatinib in Patients with Advanced Hepatocellular Carcinoma (RESCUE): A Nonrandomized, Open-label, Phase II Trial

Jianming Xu, Jie Shen, Shanzhi Gu, Yun Zhang, Lihua Wu, Jian Wu, Guoliang Shao, Yanqiao Zhang, Li Xu, Tao Yin, Jingfeng Liu, Zhenggang Ren, Jianping Xiong, Xianhai Mao, Ling Zhang, Jiayin Yang, Lequn Li, Xiaoming Chen, Zhiming Wang, Kangsheng Gu, Xi Chen, Zhanyu Pan, Kuansheng Ma, Xinmin Zhou, Zujiang Yu, Enxiao Li, Guowen Yin, Xiao Zhang, Shuni Wang, Quanren Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (4): 1003–1011.
https://doi.org/10.1158/1078-0432.CCR-20-2571
Published: 15 February 2021
View article titled, Camrelizumab in Combination with Apatinib in Patients with Advanced Hepatocellular Carcinoma (RESCUE): A Nonrandomized, Open-label, Phase II Trial
Open the PDF for Camrelizumab in Combination with Apatinib in Patients with Advanced Hepatocellular Carcinoma (RESCUE): A Nonrandomized, Open-label, Phase II Trial in another window
Includes: Supplementary data
Journal Articles

Primary Preclinical and Clinical Evaluation of 68Ga-DOTA-TMVP1 as a Novel VEGFR-3 PET Imaging Radiotracer in Gynecological Cancer

Fei Li, Zhenzhong Zhang, Jiong Cai, Xi Chen, Ying Zhou, Xiangyi Ma, Qingjian Dong, Fang Li, Ling Xi
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (6): 1318–1326.
https://doi.org/10.1158/1078-0432.CCR-19-1845
Published: 13 March 2020
View article titled, Primary Preclinical and Clinical Evaluation of <sup>68</sup>Ga-DOTA-TMVP1 as a Novel VEGFR-3 PET Imaging Radiotracer in Gynecological Cancer
Open the PDF for Primary Preclinical and Clinical Evaluation of <sup>68</sup>Ga-DOTA-TMVP1 as a Novel VEGFR-3 PET Imaging Radiotracer in Gynecological Cancer in another window
Includes: Supplementary data
Journal Articles

Genetic Polymorphisms Predisposing the Interleukin 6–Induced APOBEC3B-UNG Imbalance Increase HCC Risk via Promoting the Generation of APOBEC-Signature HBV Mutations

Wenbin Liu, Jianfeng Wu, Fan Yang, Longteng Ma, Chong Ni, Xiaomei Hou, Ling Wang, Aijing Xu, Jiahui Song, Yang Deng, Linfeng Xian, Zixiong Li, Shuo Wang, Xi Chen, Jianhua Yin, Xue Han, Chengzhong Li, Jun Zhao, Guangwen Cao
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5525–5536.
https://doi.org/10.1158/1078-0432.CCR-18-3083
Published: 13 September 2019
View article titled, Genetic Polymorphisms Predisposing the Interleukin 6–Induced APOBEC3B-UNG Imbalance Increase HCC Risk via Promoting the Generation of APOBEC-Signature HBV Mutations
Open the PDF for Genetic Polymorphisms Predisposing the Interleukin 6–Induced APOBEC3B-UNG Imbalance Increase HCC Risk via Promoting the Generation of APOBEC-Signature HBV Mutations in another window
Includes: Supplementary data
Journal Articles

SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance

Isaac Wasserman, Lik Hang Lee, Shuji Ogino, Michael R. Marco, Chao Wu, Xi Chen, Jashodeep Datta, Eran Sadot, Bryan Szeglin, Jose G. Guillem, Philip B. Paty, Martin R. Weiser, Garrett M. Nash, Leonard Saltz, Afsar Barlas, Katia Manova-Todorova, Srijaya Prakash Babu Uppada, Arthur E. Elghouayel, Peter Ntiamoah, Jonathan N. Glickman, Tsuyoshi Hamada, Keisuke Kosumi, Kentaro Inamura, Andrew T. Chan, Reiko Nishihara, Andrea Cercek, Karuna Ganesh, Nancy E. Kemeny, Punita Dhawan, Rona Yaeger, Charles L. Sawyers, Julio Garcia-Aguilar, Marios Giannakis, Jinru Shia, J. Joshua Smith
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1948–1956.
https://doi.org/10.1158/1078-0432.CCR-18-1726
Published: 15 March 2019
View article titled, SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance
Open the PDF for SMAD4 Loss in Colorectal Cancer Patients Correlates with Recurrence, Loss of Immune Infiltrate, and Chemoresistance in another window
Includes: Supplementary data
Journal Articles

Abstract B54: Targeting constitutively active RAS signaling in high-grade serous ovarian carcinoma (HGSOC) with ADT-006, a novel small molecule that blocks RAS-effector interactions

Luciana Madeira da Silva, Tyler E. Mattox, Adam B. Keeton, Bing Zhu, Kristy L. Berry, Alla Musiyenko, Elaine Gavin, Kevin Lee, Veronica Ramirez-Alcantara, Yulia Y. Maxuitenko, Xi Chen, Jacob Valiyaveettil, Michael R. Boyd, Jennifer Scalici, Rodney Rocconi, Gary A. Piazza
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (1_Supplement): B54.
https://doi.org/10.1158/1557-3265.TCM17-B54
Published: 02 January 2018
View article titled, Abstract B54: Targeting constitutively active RAS signaling in high-grade serous ovarian carcinoma (HGSOC) with ADT-006, a novel small molecule that blocks RAS-effector interactions
Journal Articles

Abstract B10: Acquired resistance to afatinib plus cetuximab in EGFR-mutant lung adenocarcinoma may be mediated by EGFR overexpression and overcome by the mutant-specific EGFR inhibitor, AZD9291.

Catherine B. Meador, Hailing Jin, Elisa de Stanchina, Valentina Pirazzoli, Marc Ladanyi, Lu Wang, Xi Chen, Rosana Eisenberg, Darren Cross, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (2_Supplement): B10.
https://doi.org/10.1158/1078-0432.14AACRIASLC-B10
Published: 16 January 2014
View article titled, Abstract B10: Acquired resistance to afatinib plus cetuximab in EGFR-mutant lung adenocarcinoma may be mediated by EGFR overexpression and overcome by the mutant-specific EGFR inhibitor, AZD9291.
Journal Articles

Identification of Prognosis-Relevant Subgroups in Patients with Chemoresistant Triple-Negative Breast Cancer

Ke-Da Yu, Rui Zhu, Ming Zhan, Angel A. Rodriguez, Wei Yang, Stephen Wong, Andreas Makris, Brian D. Lehmann, Xi Chen, Ingrid Mayer, Jennifer A. Pietenpol, Zhi-Ming Shao, W. Fraser Symmans, Jenny C. Chang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (10): 2723–2733.
https://doi.org/10.1158/1078-0432.CCR-12-2986
Published: 12 May 2013
View article titled, Identification of Prognosis-Relevant Subgroups in Patients with Chemoresistant Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Characteristics of Lung Cancers Harboring NRAS Mutations

Kadoaki Ohashi, Lecia V. Sequist, Maria E. Arcila, Christine M. Lovly, Xi Chen, Charles M. Rudin, Teresa Moran, David Ross Camidge, Cindy L. Vnencak-Jones, Lynne Berry, Yumei Pan, Hidefumi Sasaki, Jeffrey A. Engelman, Edward B. Garon, Steven M. Dubinett, Wilbur A. Franklin, Gregory J. Riely, Martin L. Sos, Mark G. Kris, Dora Dias-Santagata, Marc Ladanyi, Paul A. Bunn, Jr, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (9): 2584–2591.
https://doi.org/10.1158/1078-0432.CCR-12-3173
Published: 30 April 2013
View article titled, Characteristics of Lung Cancers Harboring <em>NRAS</em> Mutations
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Includes: Supplementary data