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William Plunkett
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Journal Articles

Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers

Katrien Van Roosbroeck, Francesca Fanini, Tetsuro Setoyama, Cristina Ivan, Cristian Rodriguez-Aguayo, Enrique Fuentes-Mattei, Lianchun Xiao, Ivan Vannini, Roxana S. Redis, Lucilla D'Abundo, Xinna Zhang, Milena S. Nicoloso, Simona Rossi, Vianey Gonzalez-Villasana, Rajesha Rupaimoole, Manuela Ferracin, Fortunato Morabito, Antonino Neri, Peter P. Ruvolo, Vivian R. Ruvolo, Chad V. Pecot, Dino Amadori, Lynne Abruzzo, Steliana Calin, Xuemei Wang, M. James You, Alessandra Ferrajoli, Robert Orlowski, William Plunkett, Tara M. Lichtenberg, Ramana V. Davuluri, Ioana Berindan-Neagoe, Massimo Negrini, Ignacio I. Wistuba, Hagop M. Kantarjian, Anil K. Sood, Gabriel Lopez-Berestein, Michael J. Keating, Muller Fabbri, George A. Calin
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (11): 2891–2904.
https://doi.org/10.1158/1078-0432.CCR-16-1025
Published: 31 May 2017
View article titled, Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers
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Includes: Supplementary data
Journal Articles

HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia

Tsung-Huei Lai, Brett Ewald, Alma Zecevic, Chaomei Liu, Melanie Sulda, Dimitrios Papaioannou, Ramiro Garzon, James S. Blachly, William Plunkett, Deepa Sampath
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (14): 3537–3549.
https://doi.org/10.1158/1078-0432.CCR-15-1063
Published: 14 July 2016
View article titled, HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia
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Includes: Supplementary data
Journal Articles

Omacetaxine: A Protein Translation Inhibitor for Treatment of Chronic Myelogenous Leukemia

Varsha Gandhi, William Plunkett, Jorge E. Cortes
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (7): 1735–1740.
https://doi.org/10.1158/1078-0432.CCR-13-1283
Published: 31 March 2014
View article titled, Omacetaxine: A Protein Translation Inhibitor for Treatment of Chronic Myelogenous Leukemia
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Journal Articles

Killing of Chronic Lymphocytic Leukemia by the Combination of Fludarabine and Oxaliplatin Is Dependent on the Activity of XPF Endonuclease

Alma Zecevic, Deepa Sampath, Brett Ewald, Rong Chen, William Wierda, William Plunkett
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4731–4741.
https://doi.org/10.1158/1078-0432.CCR-10-2561
Published: 17 July 2011
View article titled, Killing of Chronic Lymphocytic Leukemia by the Combination of Fludarabine and Oxaliplatin Is Dependent on the Activity of XPF Endonuclease
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Includes: Supplementary data
Journal Articles

Targeting DNA Repair in Chronic Lymphocytic Leukemia Cells with a Novel Acyclic Nucleotide Analogue, GS-9219

Cheng-Yu Tsai, Adrian S. Ray, Daniel B. Tumas, Michael J. Keating, Hans Reiser, William Plunkett
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (11): 3760–3769.
https://doi.org/10.1158/1078-0432.CCR-08-2848
Published: 01 June 2009
View article titled, Targeting DNA Repair in Chronic Lymphocytic Leukemia Cells with a Novel Acyclic Nucleotide Analogue, GS-9219
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Includes: Supplementary data
Journal Articles

GS-9219—A Novel Acyclic Nucleotide Analogue with Potent Antineoplastic Activity in Dogs with Spontaneous Non–Hodgkin's Lymphoma

Hans Reiser, Jianying Wang, Lee Chong, William J. Watkins, Adrian S. Ray, Riri Shibata, Gabriel Birkus, Tomas Cihlar, Sylvia Wu, Bei Li, Xiaohong Liu, Ilana N. Henne, Grushenka H.I. Wolfgang, Manoj Desai, Gerald R. Rhodes, Arnold Fridland, William A. Lee, William Plunkett, David Vail, Douglas H. Thamm, Robert Jeraj, Daniel B. Tumas
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2824–2832.
https://doi.org/10.1158/1078-0432.CCR-07-2061
Published: 01 May 2008
View article titled, GS-9219—A Novel Acyclic Nucleotide Analogue with Potent Antineoplastic Activity in Dogs with Spontaneous Non–Hodgkin's Lymphoma
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Journal Articles

Clinical and Pharmacokinetic Study of Clofarabine in Chronic Lymphocytic Leukemia: Strategy for Treatment

Varsha Gandhi, William Plunkett, Peter L. Bonate, Min Du, Billie Nowak, Susan Lerner, Michael J. Keating
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (13): 4011–4017.
https://doi.org/10.1158/1078-0432.CCR-05-2664
Published: 03 July 2006
View article titled, Clinical and Pharmacokinetic Study of Clofarabine in Chronic Lymphocytic Leukemia: Strategy for Treatment
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Journal Articles

Pharmacokinetics and Pharmacodynamics of Plasma Clofarabine and Cellular Clofarabine Triphosphate in Patients with Acute Leukemias

Varsha Gandhi, Hagop Kantarjian, Stefan Faderl, Peter Bonate, Min Du, Mary Ayres, Mary Beth Rios, Michael J. Keating, William Plunkett
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (17): 6335–6342.
Published: 24 December 2003
View article titled, Pharmacokinetics and Pharmacodynamics of Plasma Clofarabine and Cellular Clofarabine Triphosphate in Patients with Acute Leukemias
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Journal Articles

Activation of a p53-mediated Apoptotic Pathway in Quiescent Lymphocytes after the Inhibition of DNA Repair by Fludarabine

V. Ashutosh Rao, William Plunkett
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (8): 3204–3212.
Published: 11 August 2003
View article titled, Activation of a p53-mediated Apoptotic Pathway in Quiescent Lymphocytes after the Inhibition of DNA Repair by Fludarabine
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Journal Articles

DNA Repair Initiated in Chronic Lymphocytic Leukemia Lymphocytes by 4-Hydroperoxycyclophosphamide Is Inhibited by Fludarabine and Clofarabine

Takahiro Yamauchi, Billie J. Nowak, Michael J. Keating, William Plunkett
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (11): 3580–3589.
Published: 01 November 2001
View article titled, DNA Repair Initiated in Chronic Lymphocytic Leukemia Lymphocytes by 4-Hydroperoxycyclophosphamide Is Inhibited by Fludarabine and Clofarabine
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Journal Articles

Expression of ERCC1 Antisense RNA Abrogates Gemcitabine-mediated Cytotoxic Synergism with Cisplatin in Human Colon Tumor Cells Defective in Mismatch Repair but Proficient in Nucleotide Excision Repair

Li-Ying Yang, Lan Li, Hong Jiang, Yu Shen, William Plunkett
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (3): 773–781.
Published: 01 March 2000
View article titled, Expression of <em>ERCC1</em> Antisense RNA Abrogates Gemcitabine-mediated Cytotoxic Synergism with Cisplatin in Human Colon Tumor Cells Defective in Mismatch Repair but Proficient in Nucleotide Excision Repair
Open the PDF for Expression of <em>ERCC1</em> Antisense RNA Abrogates Gemcitabine-mediated Cytotoxic Synergism with Cisplatin in Human Colon Tumor Cells Defective in Mismatch Repair but Proficient in Nucleotide Excision Repair in another window