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William H. Westra
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Journal Articles

Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma Surveillance

Free
André Lopes Carvalho, Rui Henrique, Carmen Jeronimo, Chetan S. Nayak, Ashok N. Reddy, Mohammad O. Hoque, Steven Chang, Mariana Brait, Wei-Wen Jiang, Michael M. Kim, Quia Claybourne, David Goldenberg, Zubair Khan, Tanbir Khan, William H. Westra, David Sidransky, Wayne Koch, Joseph A. Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4782–4789.
https://doi.org/10.1158/1078-0432.CCR-11-0324
Published: 17 July 2011
View articletitled, Detection of Promoter Hypermethylation in Salivary Rinses as a Biomarker for Head and Neck Squamous Cell Carcinoma Surveillance
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Includes: Supplementary data
Journal Articles

An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA

Free
Shahnaz Begum, Mariana Brait, Santanu Dasgupta, Kimberly L. Ostrow, Marianna Zahurak, André L. Carvalho, Joseph A. Califano, Steven N. Goodman, William H. Westra, Mohammad Obaidul Hoque, David Sidransky
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4494–4503.
https://doi.org/10.1158/1078-0432.CCR-10-3436
Published: 05 July 2011
View articletitled, An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA
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Includes: Supplementary data
Journal Articles

Integrated, Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma

Free
Chunbo Shao, Wenyue Sun, Marietta Tan, Chad A. Glazer, Sheetal Bhan, Xiaoli Zhong, Carole Fakhry, Rajni Sharma, William H. Westra, Mohammad O. Hoque, Christopher A. Moskaluk, David Sidransky, Joseph A. Califano, Patrick K. Ha
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4320–4330.
https://doi.org/10.1158/1078-0432.CCR-10-2992
Published: 05 July 2011
View articletitled, Integrated, Genome-Wide Screening for Hypomethylated Oncogenes in Salivary Gland Adenoid Cystic Carcinoma
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Journal Articles

Bcl2 and Human Papilloma Virus 16 as Predictors of Outcome following Concurrent Chemoradiation for Advanced Oropharyngeal Cancer

Free
Anthony C. Nichols, Dianne M. Finkelstein, William C. Faquin, William H. Westra, Edmund A. Mroz, Peter Kneuertz, Shahnaz Begum, William A. Michaud, Paul M. Busse, John R. Clark, James W. Rocco
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7): 2138–2146.
https://doi.org/10.1158/1078-0432.CCR-09-3185
Published: 31 March 2010
View articletitled, Bcl2 and Human Papilloma Virus 16 as Predictors of Outcome following Concurrent Chemoradiation for Advanced Oropharyngeal Cancer
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Includes: Supplementary data
Journal Articles

Accurate Classification of Non–Small Cell Lung Carcinoma Using a Novel MicroRNA-Based Approach

Free
Justin A. Bishop, Hila Benjamin, Hila Cholakh, Ayelet Chajut, Douglas P. Clark, William H. Westra
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 610–619.
https://doi.org/10.1158/1078-0432.CCR-09-2638
Published: 14 January 2010
View articletitled, Accurate Classification of Non–Small Cell Lung Carcinoma Using a Novel MicroRNA-Based Approach
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Journal Articles

Bcl-2 Blocks Cisplatin-Induced Apoptosis and Predicts Poor Outcome Following Chemoradiation Treatment in Advanced Oropharyngeal Squamous Cell Carcinoma

Free
William A. Michaud, Anthony C. Nichols, Edmund A. Mroz, William C. Faquin, John R. Clark, Shahnaz Begum, William H. Westra, Hiroshi Wada, Paul M. Busse, Leif W. Ellisen, James W. Rocco
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (5): 1645–1654.
https://doi.org/10.1158/1078-0432.CCR-08-2581
Published: 27 February 2009
View articletitled, Bcl-2 Blocks Cisplatin-Induced Apoptosis and Predicts Poor Outcome Following Chemoradiation Treatment in Advanced Oropharyngeal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma

Free
Yuri Agrawal, Wayne M. Koch, Weihong Xiao, William H. Westra, Anna L. Trivett, David E. Symer, Maura L. Gillison
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (21): 7143–7150.
https://doi.org/10.1158/1078-0432.CCR-08-0498
Published: 03 November 2008
View articletitled, Oral Human Papillomavirus Infection Before and After Treatment for Human Papillomavirus 16–Positive and Human Papillomavirus 16–Negative Head and Neck Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Identification of Genes Differentially Expressed in Benign versus Malignant Thyroid Tumors

Free
Nijaguna B. Prasad, Helina Somervell, Ralph P. Tufano, Alan P.B. Dackiw, Michael R. Marohn, Joseph A. Califano, Yongchun Wang, William H. Westra, Douglas P. Clark, Christopher B. Umbricht, Steven K. Libutti, Martha A. Zeiger
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (11): 3327–3337.
https://doi.org/10.1158/1078-0432.CCR-07-4495
Published: 02 June 2008
View articletitled, Identification of Genes Differentially Expressed in Benign versus Malignant Thyroid Tumors
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Includes: Supplementary data
Journal Articles

Promoter Hypermethylation of Hallmark Cancer Genes in Atypical Adenomatous Hyperplasia of the Lung

Free
Julien D.F. Licchesi, William H. Westra, Craig M. Hooker, James G. Herman
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2570–2578.
https://doi.org/10.1158/1078-0432.CCR-07-2033
Published: 01 May 2008
View articletitled, Promoter Hypermethylation of Hallmark Cancer Genes in Atypical Adenomatous Hyperplasia of the Lung
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Includes: Supplementary data
Journal Articles

Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck

Free
William H. Westra, Janis M. Taube, M.L. Poeta, Shanaz Begum, David Sidransky, Wayne M. Koch
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (2): 366–369.
https://doi.org/10.1158/1078-0432.CCR-07-1402
Published: 25 January 2008
View articletitled, Inverse Relationship between Human Papillomavirus-16 Infection and Disruptive p53 Gene Mutations in Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Evaluation of Promoter Hypermethylation Detection in Body Fluids as a Screening/Diagnosis Tool for Head and Neck Squamous Cell Carcinoma

Free
André Lopes Carvalho, Carmen Jeronimo, Michael M. Kim, Rui Henrique, Zhe Zhang, Mohammad O. Hoque, Steve Chang, Mariana Brait, Chetan S. Nayak, Wei-Wen Jiang, Quia Claybourne, Yutaka Tokumaru, Juna Lee, David Goldenberg, Elizabeth Garrett-Mayer, Steven Goodman, Chul-so Moon, Wayne Koch, William H. Westra, David Sidransky, Joseph A. Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (1): 97–107.
https://doi.org/10.1158/1078-0432.CCR-07-0722
Published: 02 January 2008
View articletitled, Evaluation of Promoter Hypermethylation Detection in Body Fluids as a Screening/Diagnosis Tool for Head and Neck Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Mitochondrial Mutations Are a Late Event in the Progression of Head and Neck Squamous Cell Cancer

Free
Suhail K. Mithani, Janis M. Taube, Shaoyu Zhou, Ian M. Smith, Wayne M. Koch, William H. Westra, Joseph A. Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4331–4335.
https://doi.org/10.1158/1078-0432.CCR-06-2613
Published: 01 August 2007
View articletitled, Mitochondrial Mutations Are a Late Event in the Progression of Head and Neck Squamous Cell Cancer
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Journal Articles

Detection of Human Papillomavirus-16 in Fine-Needle Aspirates to Determine Tumor Origin in Patients with Metastatic Squamous Cell Carcinoma of the Head and Neck

Free
Shahnaz Begum, Maura L. Gillison, Theresa L. Nicol, William H. Westra
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (4): 1186–1191.
https://doi.org/10.1158/1078-0432.CCR-06-1690
Published: 22 February 2007
View articletitled, Detection of Human Papillomavirus-16 in Fine-Needle Aspirates to Determine Tumor Origin in Patients with Metastatic Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Fluorescence Visualization in Oral Neoplasia: Shedding Light on an Old Problem

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William H. Westra, David Sidransky
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (22): 6594–6597.
https://doi.org/10.1158/1078-0432.CCR-06-2253
Published: 22 November 2006
View articletitled, Fluorescence Visualization in Oral Neoplasia: Shedding Light on an Old Problem
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Journal Articles

Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients

Free
Wei-Wen Jiang, Eli Rosenbaum, Elizabeth Mambo, Marianna Zahurak, Brett Masayesva, Andre Lopes Carvalho, Shaoyu Zhou, William H. Westra, Anthony J. Alberg, David Sidransky, Wayne Koch, Joseph A. Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (5): 1564–1569.
https://doi.org/10.1158/1078-0432.CCR-05-1471
Published: 06 March 2006
View articletitled, Decreased Mitochondrial DNA Content in Posttreatment Salivary Rinses from Head and Neck Cancer Patients
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Journal Articles

Tissue Distribution of Human Papillomavirus 16 DNA Integration in Patients with Tonsillar Carcinoma

Free
Shahnaz Begum, Dengfeng Cao, Maura Gillison, Marianna Zahurak, William H. Westra
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (16): 5694–5699.
https://doi.org/10.1158/1078-0432.CCR-05-0587
Published: 22 August 2005
View articletitled, Tissue Distribution of Human Papillomavirus 16 DNA Integration in Patients with Tonsillar Carcinoma
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Journal Articles

Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer

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Wei-Wen Jiang, Brett Masayesva, Marianna Zahurak, Andre Lopes Carvalho, Eli Rosenbaum, Elizabeth Mambo, Shaoyu Zhou, Khalid Minhas, Nicole Benoit, William H. Westra, Anthony Alberg, David Sidransky, Wayne Koch, Joseph Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (7): 2486–2491.
https://doi.org/10.1158/1078-0432.CCR-04-2147
Published: 06 April 2005
View articletitled, Increased Mitochondrial DNA Content in Saliva Associated with Head and Neck Cancer
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Journal Articles

Toward Early Oral Cancer Detection using Gene Expression Profiling of Saliva: A Thoroughfare or Dead End?

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William H. Westra, Joseph Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (24): 8130–8131.
https://doi.org/10.1158/1078-0432.CCR-04-1906
Published: 28 December 2004
View articletitled, Toward Early Oral Cancer Detection using Gene Expression Profiling of Saliva: A Thoroughfare or Dead End?
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Journal Articles

Mitochondrial DNA Quantity Increases with Histopathologic Grade in Premalignant and Malignant Head and Neck Lesions

Free
Michael M. Kim, John D. Clinger, Brett G. Masayesva, Patrick K. Ha, Marianna L. Zahurak, William H. Westra, Joseph A. Califano
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (24): 8512–8515.
https://doi.org/10.1158/1078-0432.CCR-04-0734
Published: 28 December 2004
View articletitled, Mitochondrial DNA Quantity Increases with Histopathologic Grade in Premalignant and Malignant Head and Neck Lesions
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Journal Articles

Human Telomerase Reverse Transcriptase Gene Expression and the Surgical Management of Suspicious Thyroid Tumors

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Christopher B. Umbricht, George T. Conrad, Douglas P. Clark, William H. Westra, Dañelle C. Smith, Marianna Zahurak, Motoyasu Saji, Robert C. Smallridge, Steven Goodman, Martha A. Zeiger
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (17): 5762–5768.
https://doi.org/10.1158/1078-0432.CCR-03-0389
Published: 08 September 2004
View articletitled, Human Telomerase Reverse Transcriptase Gene Expression and the Surgical Management of Suspicious Thyroid Tumors
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