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William Gooding
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Journal Articles

Phase I Trial Combining Chemokine-Targeting with Loco-Regional Chemoimmunotherapy for Recurrent, Platinum-Sensitive Ovarian Cancer Shows Induction of CXCR3 Ligands and Markers of Type 1 Immunity

Brian Orr, Haider Mahdi, Yusi Fang, Mary Strange, Ibrahim Uygun, Mainpal Rana, Lixin Zhang, Adria Suarez Mora, Alexandra Pusateri, Esther Elishaev, Chaeryon Kang, George Tseng, William Gooding, Robert P. Edwards, Pawel Kalinski, Anda M. Vlad
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (10): 2038–2049.
https://doi.org/10.1158/1078-0432.CCR-21-3659
Published: 13 May 2022
View article titled, Phase I Trial Combining Chemokine-Targeting with Loco-Regional Chemoimmunotherapy for Recurrent, Platinum-Sensitive Ovarian Cancer Shows Induction of CXCR3 Ligands and Markers of Type 1 Immunity
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Includes: Supplementary data
Journal Articles

Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer

Patrick J. Schuler, Malgorzata Harasymczuk, Carmen Visus, Albert DeLeo, Sumita Trivedi, Yu Lei, Athanassios Argiris, William Gooding, Lisa H. Butterfield, Theresa L. Whiteside, Robert L. Ferris
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (9): 2433–2444.
https://doi.org/10.1158/1078-0432.CCR-13-2617
Published: 30 April 2014
View article titled, Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer
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Includes: Supplementary data
Journal Articles

The Immune Signature of CD8+CCR7+ T Cells in the Peripheral Circulation Associates with Disease Recurrence in Patients with HNSCC

Malgorzata Czystowska, William Gooding, Miroslaw J. Szczepanski, Andres Lopez-Abaitero, Robert L. Ferris, Jonas T. Johnson, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (4): 889–899.
https://doi.org/10.1158/1078-0432.CCR-12-2191
Published: 14 February 2013
View article titled, The Immune Signature of CD8<sup>+</sup>CCR7<sup>+</sup> T Cells in the Peripheral Circulation Associates with Disease Recurrence in Patients with HNSCC
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Includes: Supplementary data
Journal Articles

XPF Expression Correlates with Clinical Outcome in Squamous Cell Carcinoma of the Head and Neck

Alec Vaezi, XiaoZhe Wang, Shama Buch, William Gooding, Lin Wang, Raja R. Seethala, David T. Weaver, Alan D. D'Andrea, Athanassios Argiris, Marjorie Romkes, Laura J. Niedernhofer, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (16): 5513–5522.
https://doi.org/10.1158/1078-0432.CCR-11-0086
Published: 14 August 2011
View article titled, XPF Expression Correlates with Clinical Outcome in Squamous Cell Carcinoma of the Head and Neck
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Includes: Supplementary data
Journal Articles

Intraoperative qRT-PCR for Detection of Lymph Node Metastasis in Head and Neck Cancer

Robert L. Ferris, Liqiang Xi, Raja R. Seethala, Jon Chan, Shaun Desai, Benjamin Hoch, William Gooding, Tony E. Godfrey
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1858–1866.
https://doi.org/10.1158/1078-0432.CCR-10-3110
Published: 31 March 2011
View article titled, Intraoperative qRT-PCR for Detection of Lymph Node Metastasis in Head and Neck Cancer
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Includes: Supplementary data
Journal Articles

Phase II Study of Everolimus (RAD001) in Previously Treated Small Cell Lung Cancer

Ahmad Tarhini, Athanasios Kotsakis, William Gooding, Yongli Shuai, Daniel Petro, David Friedland, Chandra P. Belani, Sanja Dacic, Athanassios Argiris
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (23): 5900–5907.
https://doi.org/10.1158/1078-0432.CCR-10-0802
Published: 06 December 2010
View article titled, Phase II Study of Everolimus (RAD001) in Previously Treated Small Cell Lung Cancer
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Journal Articles

The Frequency and Suppressor Function of CD4+CD25highFoxp3+ T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck

Laura Strauss, Christoph Bergmann, William Gooding, Jonas T. Johnson, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (21): 6301–6311.
https://doi.org/10.1158/1078-0432.CCR-07-1403
Published: 01 November 2007
View article titled, The Frequency and Suppressor Function of CD4<sup>+</sup>CD25<sup>high</sup>Foxp3<sup>+</sup> T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck
Open the PDF for The Frequency and Suppressor Function of CD4<sup>+</sup>CD25<sup>high</sup>Foxp3<sup>+</sup> T Cells in the Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck in another window
Journal Articles

A Unique Subset of CD4+CD25highFoxp3+ T Cells Secreting Interleukin-10 and Transforming Growth Factor-β1 Mediates Suppression in the Tumor Microenvironment

Laura Strauss, Christoph Bergmann, Miroslaw Szczepanski, William Gooding, Jonas T. Johnson, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4345–4354.
https://doi.org/10.1158/1078-0432.CCR-07-0472
Published: 01 August 2007
View article titled, A Unique Subset of CD4<sup>+</sup>CD25<sup>high</sup>Foxp3<sup>+</sup> T Cells Secreting Interleukin-10 and Transforming Growth Factor-β1 Mediates Suppression in the Tumor Microenvironment
Open the PDF for A Unique Subset of CD4<sup>+</sup>CD25<sup>high</sup>Foxp3<sup>+</sup> T Cells Secreting Interleukin-10 and Transforming Growth Factor-β1 Mediates Suppression in the Tumor Microenvironment in another window
Journal Articles

Alterations in the T-Cell Receptor Variable β Gene–Restricted Profile of CD8+ T Lymphocytes in the Peripheral Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck

Andreas E. Albers, Carmen Visus, Takashi Tsukishiro, Robert L. Ferris, William Gooding, Theresa L. Whiteside, Albert B. De Leo
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (8): 2394–2403.
https://doi.org/10.1158/1078-0432.CCR-05-1818
Published: 25 April 2006
View article titled, Alterations in the T-Cell Receptor Variable β Gene–Restricted Profile of CD8<sup>+</sup> T Lymphocytes in the Peripheral Circulation of Patients with Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Defects in the Human Leukocyte Antigen Class I Antigen Processing Machinery in Head and Neck Squamous Cell Carcinoma: Association with Clinical Outcome

Markus Meissner, Torsten E. Reichert, Martin Kunkel, William Gooding, Theresa L. Whiteside, Soldano Ferrone, Barbara Seliger
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (7): 2552–2560.
https://doi.org/10.1158/1078-0432.CCR-04-2146
Published: 06 April 2005
View article titled, Defects in the Human Leukocyte Antigen Class I Antigen Processing Machinery in Head and Neck Squamous Cell Carcinoma: Association with Clinical Outcome
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Journal Articles

Effect of Human Papillomavirus-16 Infection on CD8+ T-Cell Recognition of a Wild-Type Sequence p53264–272 Peptide in Patients with Squamous Cell Carcinoma of the Head and Neck

Nicky Sirianni, Patrick K. Ha, Mattias Oelke, Joseph Califano, William Gooding, William Westra, Theresa L. Whiteside, Wayne M. Koch, Jonathan P. Schneck, Albert DeLeo, Robert L. Ferris
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (20): 6929–6937.
https://doi.org/10.1158/1078-0432.CCR-04-0672
Published: 22 October 2004
View article titled, Effect of Human Papillomavirus-16 Infection on CD8+ T-Cell Recognition of a Wild-Type Sequence p53<sub>264–272</sub> Peptide in Patients with Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Decreased Absolute Counts of T Lymphocyte Subsets and Their Relation to Disease in Squamous Cell Carcinoma of the Head and Neck

Iris Kuss, Bridget Hathaway, Robert L. Ferris, William Gooding, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (11): 3755–3762.
https://doi.org/10.1158/1078-0432.CCR-04-0054
Published: 01 June 2004
View article titled, Decreased Absolute Counts of T Lymphocyte Subsets and Their Relation to Disease in Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Enzyme-linked Immunospot, Cytokine Flow Cytometry, and Tetramers in the Detection of T-Cell Responses to a Dendritic Cell-based Multipeptide Vaccine in Patients with Melanoma

Theresa L. Whiteside, Yongxiang Zhao, Takashi Tsukishiro, Elaine M. Elder, William Gooding, Joseph Baar
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 641–649.
Published: 01 February 2003
View article titled, Enzyme-linked Immunospot, Cytokine Flow Cytometry, and Tetramers in the Detection of T-Cell Responses to a Dendritic Cell-based Multipeptide Vaccine in Patients with Melanoma
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Journal Articles

Signaling Abnormalities, Apoptosis, and Reduced Proliferation of Circulating and Tumor-infiltrating Lymphocytes in Patients with Oral Carcinoma

Torsten E. Reichert, Laura Strauss, Eva M. Wagner, William Gooding, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (10): 3137–3145.
Published: 01 October 2002
View article titled, Signaling Abnormalities, Apoptosis, and Reduced Proliferation of Circulating and Tumor-infiltrating Lymphocytes in Patients with Oral Carcinoma
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Journal Articles

Spontaneous Apoptosis of Circulating T Lymphocytes in Patients with Head and Neck Cancer and Its Clinical Importance

Thomas K. Hoffmann, Grzegorz Dworacki, Takashi Tsukihiro, Norbert Meidenbauer, William Gooding, Jonas T. Johnson, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (8): 2553–2562.
Published: 01 August 2002
View article titled, Spontaneous Apoptosis of Circulating T Lymphocytes in Patients with Head and Neck Cancer and Its Clinical Importance
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Journal Articles

Decreased ζ Chain Expression and Apoptosis in CD3+ Peripheral Blood T Lymphocytes of Patients with Melanoma

Grzegorz Dworacki, Norbert Meidenbauer, Iris Kuss, Thomas K. Hoffmann, William Gooding, Michael Lotze, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (3): 947s–957s.
Published: 01 March 2001
View article titled, Decreased ζ Chain Expression and Apoptosis in CD3<sup>+</sup> Peripheral Blood T Lymphocytes of Patients with Melanoma
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Journal Articles

Spontaneous Apoptosis of CD8+ T Lymphocytes in Peripheral Blood of Patients with Advanced Melanoma

Takao Saito, Grzegorz Dworacki, William Gooding, Michael T. Lotze, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (4): 1351–1364.
Published: 01 April 2000
View article titled, Spontaneous Apoptosis of CD8<sup>+</sup> T Lymphocytes in Peripheral Blood of Patients with Advanced Melanoma
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Journal Articles

Spontaneous ex Vivo Apoptosis of Peripheral Blood Mononuclear Cells in Patients with Head and Neck Cancer

Takao Saito, Iris Kuss, Grzegorz Dworacki, William Gooding, Jonas T. Johnson, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (6): 1263–1273.
Published: 01 June 1999
View article titled, Spontaneous <em>ex Vivo</em> Apoptosis of Peripheral Blood Mononuclear Cells in Patients with Head and Neck Cancer
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