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William E. Gooding
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Journal Articles

Phase I Trial of Cetuximab, Radiotherapy, and Ipilimumab in Locally Advanced Head and Neck Cancer

Robert L. Ferris, Jessica Moskovitz, Sheryl Kunning, Ayana T. Ruffin, Carly Reeder, James Ohr, William E. Gooding, Seungwon Kim, Brian J. Karlovits, Dario A.A. Vignali, Umamaheswar Duvvuri, Jonas T. Johnson, Daniel Petro, Dwight E. Heron, David A. Clump, Tullia C. Bruno, Julie E. Bauman
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (7): 1335–1344.
https://doi.org/10.1158/1078-0432.CCR-21-0426
Published: 01 April 2022
View article titled, Phase I Trial of Cetuximab, Radiotherapy, and Ipilimumab in Locally Advanced Head and Neck Cancer
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Journal Articles

Clinical Significance of PD-L1+ Exosomes in Plasma of Head and Neck Cancer Patients

Marie-Nicole Theodoraki, Saigopalakrishna S. Yerneni, Thomas K. Hoffmann, William E. Gooding, Theresa L. Whiteside
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (4): 896–905.
https://doi.org/10.1158/1078-0432.CCR-17-2664
Published: 14 February 2018
View article titled, Clinical Significance of PD-L1<sup>+</sup> Exosomes in Plasma of Head and Neck Cancer Patients
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Includes: Supplementary data
Journal Articles

Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies

Netanya I. Pollock, Lin Wang, Gerald Wallweber, William E. Gooding, Weidong Huang, Ahmed Chenna, John Winslow, Malabika Sen, Kara A. DeGrave, Hua Li, Yan Zeng, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4597–4606.
https://doi.org/10.1158/1078-0432.CCR-14-3338
Published: 14 October 2015
View article titled, Increased Expression of HER2, HER3, and HER2:HER3 Heterodimers in HPV-Positive HNSCC Using a Novel Proximity-Based Assay: Implications for Targeted Therapies
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Includes: Supplementary data
Journal Articles

Erlotinib, Erlotinib–Sulindac versus Placebo: A Randomized, Double-Blind, Placebo-Controlled Window Trial in Operable Head and Neck Cancer

Neil D. Gross, Julie E. Bauman, William E. Gooding, William Denq, Sufi M. Thomas, Lin Wang, Simion Chiosea, Brian L. Hood, Melanie S. Flint, Mai Sun, Thomas P. Conrads, Robert L. Ferris, Jonas T. Johnson, Seungwon Kim, Athanassios Argiris, Lori Wirth, Marina N. Nikiforova, Jill M. Siegfried, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (12): 3289–3298.
https://doi.org/10.1158/1078-0432.CCR-13-3360
Published: 12 June 2014
View article titled, Erlotinib, Erlotinib–Sulindac versus Placebo: A Randomized, Double-Blind, Placebo-Controlled Window Trial in Operable Head and Neck Cancer
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Includes: Supplementary data
Journal Articles

Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen–Specific T-cell Immunity in Head and Neck Cancer Patients

Raghvendra M. Srivastava, Steve C. Lee, Pedro A. Andrade Filho, Christopher A. Lord, Hyun-Bae Jie, H. Carter Davidson, Andrés López-Albaitero, Sandra P. Gibson, William E. Gooding, Soldano Ferrone, Robert L. Ferris
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (7): 1858–1872.
https://doi.org/10.1158/1078-0432.CCR-12-2426
Published: 02 April 2013
View article titled, Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen–Specific T-cell Immunity in Head and Neck Cancer Patients
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Includes: Supplementary data
Journal Articles

Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer

Malabika Sen, Sonali Joyce, Mary Panahandeh, Changyou Li, Sufi M. Thomas, Jessica Maxwell, Lin Wang, William E. Gooding, Daniel E. Johnson, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (18): 4986–4996.
https://doi.org/10.1158/1078-0432.CCR-12-0792
Published: 16 September 2012
View article titled, Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer
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Includes: Supplementary data
Journal Articles

Dual Blockade of EGFR and c-Met Abrogates Redundant Signaling and Proliferation in Head and Neck Carcinoma Cells

Hai Xu, Laura P. Stabile, Christopher T. Gubish, William E. Gooding, Jennifer R. Grandis, Jill M. Siegfried
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4425–4438.
https://doi.org/10.1158/1078-0432.CCR-10-3339
Published: 05 July 2011
View article titled, Dual Blockade of EGFR and c-Met Abrogates Redundant Signaling and Proliferation in Head and Neck Carcinoma Cells
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Includes: Supplementary data
Journal Articles

Early G1 Cyclin-Dependent Kinases as Prognostic Markers and Potential Therapeutic Targets in Esophageal Adenocarcinoma

Amin Ismail, Santhoshi Bandla, Marie Reveiller, Liana Toia, Zhongren Zhou, William E. Gooding, Irina Kalatskaya, Lincoln Stein, Mary D'Souza, Virginia R. Litle, Jeffrey H. Peters, Arjun Pennathur, James D. Luketich, Tony E. Godfrey
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4513–4522.
https://doi.org/10.1158/1078-0432.CCR-11-0244
Published: 05 July 2011
View article titled, Early G<sub>1</sub> Cyclin-Dependent Kinases as Prognostic Markers and Potential Therapeutic Targets in Esophageal Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

Priya Koppikar, Seung-Ho Choi, Ann Marie Egloff, Quan Cai, Shinsuke Suzuki, Maria Freilino, Hiroshi Nozawa, Sufi M. Thomas, William E. Gooding, Jill M. Siegfried, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (13): 4284–4291.
https://doi.org/10.1158/1078-0432.CCR-07-5226
Published: 01 July 2008
View article titled, Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma
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Journal Articles

Immunohistochemical Analysis of Phosphotyrosine Signal Transducer and Activator of Transcription 3 and Epidermal Growth Factor Receptor Autocrine Signaling Pathways in Head and Neck Cancers and Metastatic Lymph Nodes

Raja R. Seethala, William E. Gooding, Phoebe N. Handler, Bobby Collins, Qing Zhang, Jill M. Siegfried, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (5): 1303–1309.
https://doi.org/10.1158/1078-0432.CCR-07-1543
Published: 03 March 2008
View article titled, Immunohistochemical Analysis of Phosphotyrosine Signal Transducer and Activator of Transcription 3 and Epidermal Growth Factor Receptor Autocrine Signaling Pathways in Head and Neck Cancers and Metastatic Lymph Nodes
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Journal Articles

Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting

John C. Sok, Francesca M. Coppelli, Sufi M. Thomas, Miriam N. Lango, Sichuan Xi, Jennifer L. Hunt, Maria L. Freilino, Michael W. Graner, Carol J. Wikstrand, Darell D. Bigner, William E. Gooding, Frank B. Furnari, Jennifer R. Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (17): 5064–5073.
https://doi.org/10.1158/1078-0432.CCR-06-0913
Published: 01 September 2006
View article titled, Mutant Epidermal Growth Factor Receptor (EGFRvIII) Contributes to Head and Neck Cancer Growth and Resistance to EGFR Targeting
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Journal Articles

A Combination of Molecular Markers Accurately Detects Lymph Node Metastasis in Non–Small Cell Lung Cancer Patients

Liqiang Xi, Michael C. Coello, Virginia R. Litle, Siva Raja, William E. Gooding, Samuel A. Yousem, Talal El-Hefnawy, Rodney J. Landreneau, James D. Luketich, Tony E. Godfrey
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (8): 2484–2491.
https://doi.org/10.1158/1078-0432.CCR-05-2037
Published: 25 April 2006
View article titled, A Combination of Molecular Markers Accurately Detects Lymph Node Metastasis in Non–Small Cell Lung Cancer Patients
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Includes: Supplementary data
Journal Articles

Prediction of Lymph Node Metastasis by Analysis of Gene Expression Profiles in Primary Lung Adenocarcinomas

Liqiang Xi, James Lyons-Weiler, Michael C. Coello, Xin Huang, William E. Gooding, James D. Luketich, Tony E. Godfrey
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (11): 4128–4135.
https://doi.org/10.1158/1078-0432.CCR-04-2525
Published: 01 June 2005
View article titled, Prediction of Lymph Node Metastasis by Analysis of Gene Expression Profiles in Primary Lung Adenocarcinomas
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Journal Articles

Molecular Staging of Lymph Nodes from Patients with Esophageal Adenocarcinoma

Liqiang Xi, James D. Luketich, Siva Raja, William E. Gooding, Virginia R. Litle, Michael C. Coello, Sydney D. Finkelstein, Melissa L. Chestney, Rodney J. Landreneau, Steven J. Hughes, Tony E. Godfrey
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (3): 1099–1109.
https://doi.org/10.1158/1078-0432.1099.11.3
Published: 11 February 2005
View article titled, Molecular Staging of Lymph Nodes from Patients with Esophageal Adenocarcinoma
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Journal Articles

Abrogation of Head and Neck Squamous Cell Carcinoma Growth by Epidermal Growth Factor Receptor Ligand Fused to Pseudomonas Exotoxin Transforming Growth Factor α-PE38

Sufi M. Thomas, Qing Zeng, Michael W. Epperly, William E. Gooding, Ira Pastan, Qing Cheng Wang, Joel Greenberger, Jennifer Rubin Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (20): 7079–7087.
https://doi.org/10.1158/1078-0432.CCR-04-0587
Published: 22 October 2004
View article titled, Abrogation of Head and Neck Squamous Cell Carcinoma Growth by Epidermal Growth Factor Receptor Ligand Fused to <em>Pseudomonas</em> Exotoxin Transforming Growth Factor α-PE38
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Journal Articles

Antitumor Effects of Epidermal Growth Factor Receptor Antisense Oligonucleotides in Combination with Docetaxel in Squamous Cell Carcinoma of the Head and Neck

Hideo Niwa, Abbey L. Wentzel, Mengfeng Li, William E. Gooding, Vivian Wai Yan Lui, Jennifer Rubin Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (13): 5028–5035.
Published: 27 October 2003
View article titled, Antitumor Effects of Epidermal Growth Factor Receptor Antisense Oligonucleotides in Combination with Docetaxel in Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Prognostic Value of Quantitative Reverse Transcription-Polymerase Chain Reaction in Lymph Node-negative Esophageal Cancer Patients

Tony E. Godfrey, Siva Raja, Sydney D. Finkelstein, William E. Gooding, Lori A. Kelly, James D. Luketich
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (12): 4041–4048.
Published: 01 December 2001
View article titled, Prognostic Value of Quantitative Reverse Transcription-Polymerase Chain Reaction in Lymph Node-negative Esophageal Cancer Patients
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Journal Articles

Human Leukocyte Antigen Class I Allelic and Haplotype Loss in Squamous Cell Carcinoma of the Head and Neck: Clinical and Immunogenetic Consequences

Jennifer Rubin Grandis, Dewayne M. Falkner, Mona F. Melhem, William E. Gooding, Stephanie D. Drenning, Penelope A. Morel
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (7): 2794–2802.
Published: 01 July 2000
View article titled, Human Leukocyte Antigen Class I Allelic and Haplotype Loss in Squamous Cell Carcinoma of the Head and Neck: Clinical and Immunogenetic Consequences
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Journal Articles

Determination of Intermediate Biomarker Expression Levels by Quantitative Reverse Transcription-Polymerase Chain Reaction in Oral Mucosa of Cancer Patients Treated with Liarozole

Qing Zeng, David C. Smith, Todd J. Suscovich, William E. Gooding, Donald L. Trump, Jennifer Rubin Grandis
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (6): 2245–2251.
Published: 01 June 2000
View article titled, Determination of Intermediate Biomarker Expression Levels by Quantitative Reverse Transcription-Polymerase Chain Reaction in Oral Mucosa of Cancer Patients Treated with Liarozole
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