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Willem W. Overwijk
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Journal Articles

Fucosylation Enhances the Efficacy of Adoptively Transferred Antigen-Specific Cytotoxic T Lymphocytes

Free
Gheath Alatrash, Na Qiao, Mao Zhang, Madhushree Zope, Alexander A. Perakis, Pariya Sukhumalchandra, Anne V. Philips, Haven R. Garber, Celine Kerros, Lisa S. St. John, Maria R. Khouri, Hiep Khong, Karen Clise-Dwyer, Leonard P. Miller, Steve Wolpe, Willem W. Overwijk, Jeffrey J. Molldrem, Qing Ma, Elizabeth J. Shpall, Elizabeth A. Mittendorf
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (8): 2610–2620.
https://doi.org/10.1158/1078-0432.CCR-18-1527
Published: 15 April 2019
View articletitled, Fucosylation Enhances the Efficacy of Adoptively Transferred Antigen-Specific Cytotoxic T Lymphocytes
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Includes: Supplementary data
Journal Articles

Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter

Free
Krit Ritthipichai, Cara L. Haymaker, Melisa Martinez, Andrew Aschenbrenner, Xiaohui Yi, Minying Zhang, Charuta Kale, Luis M. Vence, Jason Roszik, Yared Hailemichael, Willem W. Overwijk, Navin Varadarajan, Roza Nurieva, Laszlo G. Radvanyi, Patrick Hwu, Chantale Bernatchez
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (20): 6151–6164.
https://doi.org/10.1158/1078-0432.CCR-16-1217
Published: 12 October 2017
View articletitled, Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter
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Includes: Multimedia, Supplementary data
Journal Articles

BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma

Free
Dennie T. Frederick, Adriano Piris, Alexandria P. Cogdill, Zachary A. Cooper, Cecilia Lezcano, Cristina R. Ferrone, Devarati Mitra, Andrea Boni, Lindsay P. Newton, Chengwen Liu, Weiyi Peng, Ryan J. Sullivan, Donald P. Lawrence, F. Stephen Hodi, Willem W. Overwijk, Gregory Lizée, George F. Murphy, Patrick Hwu, Keith T. Flaherty, David E. Fisher, Jennifer A. Wargo
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (5): 1225–1231.
https://doi.org/10.1158/1078-0432.CCR-12-1630
Published: 03 March 2013
View articletitled, BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
Open the PDF for BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma in another window
Includes: Supplementary data
Journal Articles

BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice

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Chengwen Liu, Weiyi Peng, Chunyu Xu, Yanyan Lou, Minying Zhang, Jennifer A. Wargo, Jie Qing Chen, Haiyan S. Li, Stephanie S. Watowich, Yan Yang, Dennie Tompers Frederick, Zachary A. Cooper, Rina M. Mbofung, Mayra Whittington, Keith T. Flaherty, Scott E. Woodman, Michael A. Davies, Laszlo G. Radvanyi, Willem W. Overwijk, Gregory Lizée, Patrick Hwu
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (2): 393–403.
https://doi.org/10.1158/1078-0432.CCR-12-1626
Published: 16 January 2013
View articletitled, BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice
Open the PDF for BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice in another window
Includes: Supplementary data
Journal Articles

Impact of Clinical and Pathologic Features on Tumor-Infiltrating Lymphocyte Expansion from Surgically Excised Melanoma Metastases for Adoptive T-cell Therapy

Free
Richard W. Joseph, Vijay R. Peddareddigari, Ping Liu, Priscilla W. Miller, Willem W. Overwijk, Nebiyou B. Bekele, Merrick I. Ross, Jeffrey E. Lee, Jeffrey E. Gershenwald, Anthony Lucci, Victor G. Prieto, John D. McMannis, Nicholas Papadopoulos, Kevin Kim, Jade Homsi, Agop Bedikian, Wen-Jen Hwu, Patrick Hwu, Laszlo G. Radvanyi
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (14): 4882–4891.
https://doi.org/10.1158/1078-0432.CCR-10-2769
Published: 17 July 2011
View articletitled, Impact of Clinical and Pathologic Features on Tumor-Infiltrating Lymphocyte Expansion from Surgically Excised Melanoma Metastases for Adoptive T-cell Therapy
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Journal Articles

Transduction of Tumor-Specific T Cells with CXCR2 Chemokine Receptor Improves Migration to Tumor and Antitumor Immune Responses

Free
Weiyi Peng, Yang Ye, Brian A. Rabinovich, Chengwen Liu, Yanyan Lou, Minying Zhang, Mayra Whittington, Yan Yang, Willem W. Overwijk, Gregory Lizée, Patrick Hwu
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (22): 5458–5468.
https://doi.org/10.1158/1078-0432.CCR-10-0712
Published: 14 November 2010
View articletitled, Transduction of Tumor-Specific T Cells with CXCR2 Chemokine Receptor Improves Migration to Tumor and Antitumor Immune Responses
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Journal Articles

Inhibition of p-STAT3 Enhances IFN-α Efficacy against Metastatic Melanoma in a Murine Model

Free
Ling-Yuan Kong, Alexander Gelbard, Jun Wei, Chantal Reina-Ortiz, Yongtao Wang, Eric C. Yang, Yared Hailemichael, Izabela Fokt, Arumugam Jayakumar, Wei Qiao, Gregory N. Fuller, Willem W. Overwijk, Waldemar Priebe, Amy B. Heimberger
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (9): 2550–2561.
https://doi.org/10.1158/1078-0432.CCR-10-0279
Published: 28 April 2010
View articletitled, Inhibition of p-STAT3 Enhances IFN-α Efficacy against Metastatic Melanoma in a Murine Model
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Journal Articles

Targeted Inhibition of Inducible Nitric Oxide Synthase Inhibits Growth of Human Melanoma In vivo and Synergizes with Chemotherapy

Free
Andrew G. Sikora, Alexander Gelbard, Michael A. Davies, Daisuke Sano, Suhendan Ekmekcioglu, John Kwon, Yared Hailemichael, Padmini Jayaraman, Jeffrey N. Myers, Elizabeth A. Grimm, Willem W. Overwijk
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (6): 1834–1844.
https://doi.org/10.1158/1078-0432.CCR-09-3123
Published: 14 March 2010
View articletitled, Targeted Inhibition of Inducible Nitric Oxide Synthase Inhibits Growth of Human Melanoma In vivo and Synergizes with Chemotherapy
Open the PDF for Targeted Inhibition of Inducible Nitric Oxide Synthase Inhibits Growth of Human Melanoma In vivo and Synergizes with Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Improving Antitumor Immune Responses by Circumventing Immunoregulatory Cells and Mechanisms

Free
Gregory Lizée, Laszlo G. Radvanyi, Willem W. Overwijk, Patrick Hwu
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (16): 4794–4803.
https://doi.org/10.1158/1078-0432.CCR-06-0944
Published: 16 August 2006
View articletitled, Improving Antitumor Immune Responses by Circumventing Immunoregulatory Cells and Mechanisms
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Journal Articles

Immunosuppression in Melanoma Immunotherapy: Potential Opportunities for Intervention

Free
Gregory Lizée, Laszlo G. Radvanyi, Willem W. Overwijk, Patrick Hwu
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (7): 2359s–2365s.
https://doi.org/10.1158/1078-0432.CCR-05-2537
Published: 11 April 2006
View articletitled, Immunosuppression in Melanoma Immunotherapy: Potential Opportunities for Intervention
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