1-11 of 11
Wells Messersmith
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma

Miles Piper, Benjamin Van Court, Adam Mueller, Shuichi Watanabe, Thomas Bickett, Shilpa Bhatia, Laurel B. Darragh, Max Mayeda, Diemmy Nguyen, Jacob Gadwa, Michael Knitz, Sophia Corbo, Rustain Morgan, Jung-Jae Lee, Alexander Dent, Karyn Goodman, Wells Messersmith, Richard Schulick, Marco Del Chiaro, Yuwen Zhu, Ross M. Kedl, Laurel Lenz, Sana D. Karam
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 1013–1026.
https://doi.org/10.1158/1078-0432.CCR-21-2767
Published: 03 March 2022
View article titled, Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma
Open the PDF for Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer

Efrat Dotan, Dana B. Cardin, Heinz-Josef Lenz, Wells Messersmith, Bert O'Neil, Steven J. Cohen, Crystal S. Denlinger, Safi Shahda, Igor Astsaturov, Ann M. Kapoun, Rainer K. Brachmann, Shailaja Uttamsingh, Robert J. Stagg, Colin Weekes
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (20): 5348–5357.
https://doi.org/10.1158/1078-0432.CCR-20-0489
Published: 15 October 2020
View article titled, Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer
Open the PDF for Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer in another window
Journal Articles

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

Antonio Jimeno, Michael Gordon, Rashmi Chugh, Wells Messersmith, David Mendelson, Jakob Dupont, Robert Stagg, Ann M. Kapoun, Lu Xu, Shailaja Uttamsingh, Rainer K. Brachmann, David C. Smith
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24): 7490–7497.
https://doi.org/10.1158/1078-0432.CCR-17-2157
Published: 14 December 2017
View article titled, A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors
Open the PDF for A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors in another window
Journal Articles

Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody–Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies

Khaldoun Almhanna, Thea Kalebic, Cristina Cruz, Jason E. Faris, David P. Ryan, JungAh Jung, Tim Wyant, Adedigbo A. Fasanmade, Wells Messersmith, Jordi Rodon
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (20): 5049–5057.
https://doi.org/10.1158/1078-0432.CCR-15-2474
Published: 13 October 2016
View article titled, Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody–Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies
Open the PDF for Phase I Study of the Investigational Anti-Guanylyl Cyclase Antibody–Drug Conjugate TAK-264 (MLN0264) in Adult Patients with Advanced Gastrointestinal Malignancies in another window
Journal Articles

Abstract IA20: Challenges, opportunities, and lessons learned in the bench-to-bedside translation of xenopatient studies

S. Gail Eckhardt, Todd Pitts, Aik Choon Tan, Stacey Bagby, John Arcaroli, Anna Capasso, Kit Wong, Peter Klauck, Wells Messersmith, S Lindsey Davis, Christopher Lieu, Stephen Leong, Jennifer Diamond, John Tentler
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (16_Supplement): IA20.
https://doi.org/10.1158/1557-3265.PDX16-IA20
Published: 15 August 2016
View article titled, Abstract IA20: Challenges, opportunities, and lessons learned in the bench-to-bedside translation of xenopatient studies
Journal Articles

Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors

Dejan Juric, Rodrigo Dienstmann, Andres Cervantes, Manuel Hidalgo, Wells Messersmith, George R. Blumenschein, Jr, Josep Tabernero, Desamparados Roda, Antonio Calles, Antonio Jimeno, Xiaodong Wang, Sandra Sanabria Bohórquez, Cecilia Leddy, Catherine Littman, Amy V. Kapp, David S. Shames, Elicia Penuel, Lukas C. Amler, Andrea Pirzkall, José Baselga
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (11): 2462–2470.
https://doi.org/10.1158/1078-0432.CCR-14-2412
Published: 31 May 2015
View article titled, Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors
Open the PDF for Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors in another window
Journal Articles

Individualizing therapy using direct xenografting of pancreas cancers: a multi-modality approach

Antonio Jimeno, Belen Rubio-Viqueira, Xiang Feng Zhang, Audrey Chan, Saeed Khan, Kris Galvin, Wells Messersmith, Soner Altiok, Peter Kulesza, Anirban Maitra, Manuel Hidalgo
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19_Supplement): B2.
Published: 15 August 2014
View article titled, Individualizing therapy using direct xenografting of pancreas cancers: a multi-modality approach
Journal Articles

Early prediction of antiepidermal growth factor receptor therapy with 18[F]FDG-PET: A preclinical and clinical correlation.

Wen Ma, Antonio Jimeno, Peter Kulesza, Audrey Chan, Xiang Feng Zhang, Jenna Wheelhouse, Heather Jacene, Wells Messersmith, Chris Endres, Maura Gillison, Martin Pomper, Arlene Forastiere, Manuel Hidalgo
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): B35.
Published: 15 August 2014
View article titled, Early prediction of antiepidermal growth factor receptor therapy with 18[F]FDG-PET: A preclinical and clinical correlation.
Journal Articles

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor,in Patients with Advanced Solid Tumors

Jennifer R. Diamond, Bruno R. Bastos, Ryan J. Hansen, Daniel L. Gustafson, S. Gail Eckhardt, Eunice L. Kwak, Shuchi S. Pandya, Graham C. Fletcher, Todd M. Pitts, Gillian N. Kulikowski, Mark Morrow, Jamie Arnott, Mark R. Bray, Carolyn Sidor, Wells Messersmith, Geoffrey I. Shapiro
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 849–860.
https://doi.org/10.1158/1078-0432.CCR-10-2144
Published: 15 February 2011
View article titled, Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor,in Patients with Advanced Solid Tumors
Open the PDF for Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor,in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

A Phase I Study of EKB-569 in Combination with Capecitabine in Patients with Advanced Colorectal Cancer

Dan Laheru, Gary Croghan, Ronald Bukowski, Michelle Rudek, Wells Messersmith, Charles Erlichman, Robert Pelley, Antonio Jimeno, Ross Donehower, Joseph Boni, Richat Abbas, Patricia Martins, Charles Zacharchuk, Manuel Hidalgo
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (17): 5602–5609.
https://doi.org/10.1158/1078-0432.CCR-08-0433
Published: 02 September 2008
View article titled, A Phase I Study of EKB-569 in Combination with Capecitabine in Patients with Advanced Colorectal Cancer
Open the PDF for A Phase I Study of EKB-569 in Combination with Capecitabine in Patients with Advanced Colorectal Cancer in another window
Journal Articles

An In vivo Platform for Translational Drug Development in Pancreatic Cancer

Belen Rubio-Viqueira, Antonio Jimeno, George Cusatis, Xianfeng Zhang, Christine Iacobuzio-Donahue, Collins Karikari, Chanjusn Shi, Kathleen Danenberg, Peter V. Danenberg, Hidekazu Kuramochi, Koji Tanaka, Sharat Singh, Hossein Salimi-Moosavi, Nadia Bouraoud, Maria L. Amador, Soner Altiok, Piotr Kulesza, Charles Yeo, Wells Messersmith, James Eshleman, Ralph H. Hruban, Anirban Maitra, Manuel Hidalgo
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (15): 4652–4661.
https://doi.org/10.1158/1078-0432.CCR-06-0113
Published: 09 August 2006
View article titled, An <em>In vivo</em> Platform for Translational Drug Development in Pancreatic Cancer
Open the PDF for An <em>In vivo</em> Platform for Translational Drug Development in Pancreatic Cancer in another window
Includes: Supplementary data