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Journal Articles

Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer

Open Access
Kalpit Shah, Matthew H. Secrest, Wei Zhou, Shu Wang, Dan Canter, Yuxiang Zhang, Dexter Jin, Ethan Sokol, Malgorzata Nowicka, Armande Ang Houle, Ciara Metcalfe, Steven Gendreau, Carsten Schröder, Matthew Wongchenko, Gerhardt Attard
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF15.
https://doi.org/10.1158/1078-0432.CCR-24-1812
Published: 23 May 2025
View articletitled, Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer
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Includes: Supplementary data
Journal Articles

Pyrotinib Treatment in Patients With HER2-positive Metastatic Breast Cancer and Brain Metastasis: Exploratory Final Analysis of Real-World, Multicenter Data

Open Access
Munawar Anwar, Qitong Chen, Dengjie Ouyang, Shouman Wang, Ning Xie, Quchang Ouyang, Peizhi Fan, Liyuan Qian, Gannong Chen, Enxiang Zhou, Lei Guo, Xiaowen Gu, Boning Ding, Xiaohong Yang, Liping Liu, Chao Deng, Zhi Xiao, Jing Li, Yunqi Wang, Shan Zeng, Jinhui Hu, Wei Zhou, Bo Qiu, Zhongming Wang, Jie Weng, Mingwen Liu, Yi Li, Tiegang Tang, Jianguo Wang, Hui Zhang, Bin Dai, Wuping Tang, Tao Wu, Maoliang Xiao, Xiantao Li, Hailong Liu, Lai Li, Wenjun Yi
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (16): 4634–4641.
https://doi.org/10.1158/1078-0432.CCR-21-0474
Published: 15 August 2021
View articletitled, Pyrotinib Treatment in Patients With HER2-positive Metastatic Breast Cancer and Brain Metastasis: Exploratory Final Analysis of Real-World, Multicenter Data
Open the PDF for Pyrotinib Treatment in Patients With HER2-positive Metastatic Breast Cancer and Brain Metastasis: Exploratory Final Analysis of Real-World, Multicenter Data in another window
Includes: Supplementary data
Journal Articles

ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer

Free
Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M.H. Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S. Liu, Annie N.Y. Cheung, Hextan Y.S. Ngan, David W. Chan, Wei Zheng, Wenge Zhu
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (19): 5947–5960.
https://doi.org/10.1158/1078-0432.CCR-18-4145
Published: 01 October 2019
View articletitled, ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

PRMT5-mediated H4R3sme2 Confers Cell Differentiation in Pediatric B-cell Precursor Acute Lymphoblastic Leukemia

Free
Mei Mei, Ruidong Zhang, Zhong-Wei Zhou, Zhengzhou Ying, Jincheng Wang, Han Zhang, Huyong Zheng, Shilai Bao
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (8): 2633–2643.
https://doi.org/10.1158/1078-0432.CCR-18-2342
Published: 15 April 2019
View articletitled, PRMT5-mediated H4R3sme2 Confers Cell Differentiation in Pediatric B-cell Precursor Acute Lymphoblastic Leukemia
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Includes: Supplementary data
Journal Articles

COX-2/PGE2 Axis Regulates HIF2α Activity to Promote Hepatocellular Carcinoma Hypoxic Response and Reduce the Sensitivity of Sorafenib Treatment

Free
Xiao-Feng Dong, Tian-Qi Liu, Xu-Ting Zhi, Jie Zou, Jing-Tao Zhong, Tao Li, Xiang-Lan Mo, Wei Zhou, Wen-Wen Guo, Xia Liu, Yuan-Yuan Chen, Meng-Yang Li, Xiao-Gang Zhong, Ya-Min Han, Zhong-Hao Wang, Zhao-Ru Dong
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (13): 3204–3216.
https://doi.org/10.1158/1078-0432.CCR-17-2725
Published: 01 July 2018
View articletitled, COX-2/PGE2 Axis Regulates HIF2α Activity to Promote Hepatocellular Carcinoma Hypoxic Response and Reduce the Sensitivity of Sorafenib Treatment
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Includes: Supplementary data
Journal Articles

Significant and rapid stimulation of cytotoxic T-lymphocyte (CTL) responses against Her-2/neu positive ovarian cancer

Free
Yuefei Yu, Wei Zhou, Petra Pilgrim, Everardo Cobos, Maurizio Chiriva-Internati
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (15_Supplement): A21.
Published: 15 August 2014
View articletitled, Significant and rapid stimulation of cytotoxic T-lymphocyte (CTL) responses against Her-2/neu positive ovarian cancer
Journal Articles

Abstract B8: Targeting p21-activated kinases in human lung cancer

Free
Christy C. Ong, Adrian M. Jubb, Peter M. Haverty, Wei Zhou, Adrian L. Harris, Marcia Belvin, Lori S. Friedman, Hartmut Koeppen, Klaus P. Hoeflich
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): B8.
https://doi.org/10.1158/1078-0432.12AACRIASLC-B8
Published: 01 February 2012
View articletitled, Abstract B8: Targeting p21-activated kinases in human lung cancer
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Journal Articles

Abstract A11: STRADα regulates cell polarity and invasion through PAK1 signaling in LKB1 null cells

Free
Carrie M. Eggers, Erik R. Kline, Diansheng Zhong, Wei Zhou, Adam I. Marcus
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): A11.
https://doi.org/10.1158/1078-0432.12AACRIASLC-A11
Published: 01 February 2012
View articletitled, Abstract A11: STRADα regulates cell polarity and invasion through PAK1 signaling in LKB1 null cells
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Journal Articles

In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models

Free
Klaus P. Hoeflich, Carol O'Brien, Zachary Boyd, Guy Cavet, Steve Guerrero, Kenneth Jung, Tom Januario, Heidi Savage, Elizabeth Punnoose, Tom Truong, Wei Zhou, Leanne Berry, Lesley Murray, Lukas Amler, Marcia Belvin, Lori S. Friedman, Mark R. Lackner
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4649–4664.
https://doi.org/10.1158/1078-0432.CCR-09-0317
Published: 15 July 2009
View articletitled, In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models
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Includes: Supplementary data
Journal Articles

Suppression of HER2/HER3-Mediated Growth of Breast Cancer Cells with Combinations of GDC-0941 PI3K Inhibitor, Trastuzumab, and Pertuzumab

Free
Evelyn Yao, Wei Zhou, Si Tuen Lee-Hoeflich, Tom Truong, Peter M. Haverty, Jeffrey Eastham-Anderson, Nicholas Lewin-Koh, Bert Gunter, Marcia Belvin, Lesley J. Murray, Lori S. Friedman, Mark X. Sliwkowski, Klaus P. Hoeflich
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (12): 4147–4156.
https://doi.org/10.1158/1078-0432.CCR-08-2814
Published: 15 June 2009
View articletitled, Suppression of HER2/HER3-Mediated Growth of Breast Cancer Cells with Combinations of GDC-0941 PI3K Inhibitor, Trastuzumab, and Pertuzumab
Open the PDF for Suppression of HER2/HER3-Mediated Growth of Breast Cancer Cells with Combinations of GDC-0941 PI3K Inhibitor, Trastuzumab, and Pertuzumab in another window
Includes: Supplementary data
Journal Articles

p53 Arg72Pro and MDM2 T309G Polymorphisms, Histology, and Esophageal Cancer Prognosis

Free
David W. Cescon, Penelope A. Bradbury, Kofi Asomaning, Jessica Hopkins, Rihong Zhai, Wei Zhou, Zhaoxi Wang, Matthew Kulke, Li Su, Clement Ma, Wei Xu, Ariela L. Marshall, Rebecca Suk Heist, John C. Wain, Thomas J. Lynch, Jr., David C. Christiani, Geoffrey Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (9): 3103–3109.
https://doi.org/10.1158/1078-0432.CCR-08-3120
Published: 30 April 2009
View articletitled, p53 Arg72Pro and MDM2 T309G Polymorphisms, Histology, and Esophageal Cancer Prognosis
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Journal Articles

MDM2 Promoter Polymorphism and Pancreatic Cancer Risk and Prognosis

Free
Kofi Asomaning, Amy E. Reid, Wei Zhou, Rebecca S. Heist, Rihong Zhai, Li Su, Eunice L. Kwak, Lawrence Blaszkowsky, Andrew X. Zhu, David P. Ryan, David C. Christiani, Geoffrey Liu
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (12): 4010–4015.
https://doi.org/10.1158/1078-0432.CCR-07-4187
Published: 16 June 2008
View articletitled, MDM2 Promoter Polymorphism and Pancreatic Cancer Risk and Prognosis
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Journal Articles

Vascular Endothelial Growth Factor Genotypes, Haplotypes, Gender, and the Risk of Non–Small Cell Lung Cancer

Free
Rihong Zhai, Geoffrey Liu, Wei Zhou, Li Su, Rebecca Suk Heist, Thomas J. Lynch, John C. Wain, Kofi Asomaning, Xihong Lin, David C. Christiani
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (2): 612–617.
https://doi.org/10.1158/1078-0432.CCR-07-1655
Published: 25 January 2008
View articletitled, Vascular Endothelial Growth Factor Genotypes, Haplotypes, Gender, and the Risk of Non–Small Cell Lung Cancer
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Journal Articles

Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter Hypermethylation

Free
Wen Yue, Sanja Dacic, Quanhong Sun, Rodney Landreneau, Mingzhou Guo, Wei Zhou, Jill M. Siegfried, Jian Yu, Lin Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (15): 4336–4344.
https://doi.org/10.1158/1078-0432.CCR-07-0015
Published: 01 August 2007
View articletitled, Frequent Inactivation of RAMP2, EFEMP1 and Dutt1 in Lung Cancer by Promoter Hypermethylation
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Includes: Supplementary data
Journal Articles

Second Hand Smoke Exposure and Survival in Early-Stage Non–Small-Cell Lung Cancer Patients

Free
Wei Zhou, Rebecca S. Heist, Geoffrey Liu, Kofi Asomaning, David P. Miller, Donna S. Neuberg, John C. Wain, Thomas J. Lynch, David C. Christiani
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (23): 7187–7193.
https://doi.org/10.1158/1078-0432.CCR-06-1460
Published: 04 December 2006
View articletitled, Second Hand Smoke Exposure and Survival in Early-Stage Non–Small-Cell Lung Cancer Patients
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Journal Articles

Matrix Metalloproteinase Polymorphisms and Survival in Stage I Non–Small Cell Lung Cancer

Free
Rebecca Suk Heist, Ariela L. Marshall, Geoffrey Liu, Wei Zhou, Li Su, Donna Neuberg, Thomas J. Lynch, John Wain, David C. Christiani
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (18): 5448–5453.
https://doi.org/10.1158/1078-0432.CCR-06-0262
Published: 25 September 2006
View articletitled, Matrix Metalloproteinase Polymorphisms and Survival in Stage I Non–Small Cell Lung Cancer
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Journal Articles

Effects of Nonselective Cyclooxygenase Inhibition with Low-Dose Ibuprofen on Tumor Growth, Angiogenesis, Metastasis, and Survival in a Mouse Model of Colorectal Cancer

Free
Min Yao, Wei Zhou, Simren Sangha, Andrew Albert, Albert J. Chang, Thomas C. Liu, M. Michael Wolfe
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (4): 1618–1628.
https://doi.org/10.1158/1078-0432.CCR-04-1696
Published: 02 March 2005
View articletitled, Effects of Nonselective Cyclooxygenase Inhibition with Low-Dose Ibuprofen on Tumor Growth, Angiogenesis, Metastasis, and Survival in a Mouse Model of Colorectal Cancer
Open the PDF for Effects of Nonselective Cyclooxygenase Inhibition with Low-Dose Ibuprofen on Tumor Growth, Angiogenesis, Metastasis, and Survival in a Mouse Model of Colorectal Cancer in another window
Journal Articles

Polymorphisms in ERCC1 and Grade 3 or 4 Toxicity in Non–Small Cell Lung Cancer Patients

Free
Rebecca Suk, Sarada Gurubhagavatula, Sohee Park, Wei Zhou, Li Su, Thomas J. Lynch, John C. Wain, Donna Neuberg, Geoffrey Liu, David C. Christiani
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (4): 1534–1538.
https://doi.org/10.1158/1078-0432.CCR-04-1953
Published: 02 March 2005
View articletitled, Polymorphisms in ERCC1 and Grade 3 or 4 Toxicity in Non–Small Cell Lung Cancer Patients
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Journal Articles

Excision Repair Cross-Complementation Group 1 Polymorphism Predicts Overall Survival in Advanced Non-Small Cell Lung Cancer Patients Treated With Platinum-Based Chemotherapy

Free
Wei Zhou, Sarada Gurubhagavatula, Geoffrey Liu, Sohee Park, Donna S. Neuberg, John C. Wain, Thomas J. Lynch, Li Su, David C. Christiani
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (15): 4939–4943.
https://doi.org/10.1158/1078-0432.CCR-04-0247
Published: 05 August 2004
View articletitled, Excision Repair Cross-Complementation Group 1 Polymorphism Predicts Overall Survival in Advanced Non-Small Cell Lung Cancer Patients Treated With Platinum-Based Chemotherapy
Open the PDF for Excision Repair Cross-Complementation Group 1 Polymorphism Predicts Overall Survival in Advanced Non-Small Cell Lung Cancer Patients Treated With Platinum-Based Chemotherapy in another window