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Journal Articles

A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX ± Bevacizumab versus FOLFOX ± Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study)

Feng Wang, Ming-Ming He, Jian Xiao, Yan-Qiao Zhang, Xiang-Lin Yuan, Wei-Jia Fang, Yan Zhang, Wei Wang, Xiao-Hua Hu, Zhi-Gang Ma, Yi-Chen Yao, Zhi-Xiang Zhuang, Fu-Xiang Zhou, Jie-Er Ying, Ying Yuan, Qing-Feng Zou, Zeng-Qing Guo, Xiang-Yuan Wu, Ying Jin, Zong-Jiong Mai, Zhi-Qiang Wang, Hong Qiu, Ying Guo, Si-Mei Shi, Shuang-Zhen Chen, Hui-Yan Luo, Dong-Sheng Zhang, Feng-Hua Wang, Yu-Hong Li, Rui-Hua Xu
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4232–4239.
https://doi.org/10.1158/1078-0432.CCR-22-0655
Published: 03 October 2022
View article titled, A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX ± Bevacizumab versus FOLFOX ± Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study)
Open the PDF for A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX ± Bevacizumab versus FOLFOX ± Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study) in another window
Includes: Supplementary data
Journal Articles

Abstract IA23: Molecular landscapes of hepatocellular carcinoma and cholangiocarcinoma

Xin Wei Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17_Supplement): IA23.
https://doi.org/10.1158/1557-3265.LIVERCA22-IA23
Published: 01 September 2022
View article titled, Abstract IA23: Molecular landscapes of hepatocellular carcinoma and cholangiocarcinoma
Journal Articles

Abstract PR06: Identifying regulatory transcription factors in primary liver cancer cell lineage commitment using single cell ATAC sequencing

Amanda J Craig, Lichun Ma, Sophia Heinrich, Michael Kelly, Tim Greten, Xin Wei Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17_Supplement): PR06.
https://doi.org/10.1158/1557-3265.LIVERCA22-PR06
Published: 01 September 2022
View article titled, Abstract PR06: Identifying regulatory transcription factors in primary liver cancer cell lineage commitment using single cell ATAC sequencing
Journal Articles

Stress Keratin 17 Expression in Head and Neck Cancer Contributes to Immune Evasion and Resistance to Immune-Checkpoint Blockade

Wei Wang, Taja Lozar, Athena E. Golfinos, Denis Lee, Ellery Gronski, Ella Ward-Shaw, Mitchell Hayes, Justine Y. Bruce, Randall J. Kimple, Rong Hu, Paul M. Harari, Jin Xu, Aysenur Keske, Paul M. Sondel, Megan B. Fitzpatrick, Huy Q. Dinh, Paul F. Lambert
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2953–2968.
https://doi.org/10.1158/1078-0432.CCR-21-3039
Published: 01 July 2022
View article titled, Stress Keratin 17 Expression in Head and Neck Cancer Contributes to Immune Evasion and Resistance to Immune-Checkpoint Blockade
Open the PDF for Stress Keratin 17 Expression in Head and Neck Cancer Contributes to Immune Evasion and Resistance to Immune-Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer

Giulia Siravegna, Connor J. O'Boyle, Shohreh Varmeh, Natalia Queenan, Alexa Michel, Jarrod Stein, Julia Thierauf, Peter M. Sadow, William C. Faquin, Simon K. Perry, Adam Z. Bard, Wei Wang, Daniel G. Deschler, Kevin S. Emerick, Mark A. Varvares, Jong C. Park, John R. Clark, Annie W. Chan, Vanessa Carlota Andreu Arasa, Osamu Sakai, Jochen Lennerz, Ryan B. Corcoran, Lori J. Wirth, Derrick T. Lin, A. John Iafrate, Jeremy D. Richmon, Daniel L. Faden
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 719–727.
https://doi.org/10.1158/1078-0432.CCR-21-3151
Published: 15 February 2022
View article titled, Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer
Open the PDF for Cell-Free HPV DNA Provides an Accurate and Rapid Diagnosis of HPV-Associated Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

OCaMIR—A Noninvasive, Diagnostic Signature for Early-Stage Ovarian Cancer: A Multi-cohort Retrospective and Prospective Study

Raju Kandimalla, Wei Wang, Fan Yu, Nianxin Zhou, Feng Gao, Monique Spillman, Lucie Moukova, Ondrej Slaby, Bodour Salhia, Shengtao Zhou, Xin Wang, Ajay Goel
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (15): 4277–4286.
https://doi.org/10.1158/1078-0432.CCR-21-0267
Published: 01 August 2021
View article titled, OCaMIR—A Noninvasive, Diagnostic Signature for Early-Stage Ovarian Cancer: A Multi-cohort Retrospective and Prospective Study
Open the PDF for OCaMIR—A Noninvasive, Diagnostic Signature for Early-Stage Ovarian Cancer: A Multi-cohort Retrospective and Prospective Study in another window
Includes: Supplementary data
Journal Articles

A Novel Autocrine CXCL14/ACKR2 Axis: The Achilles' Heel of Cancer Metastasis?

Qian Zhang, Nianxin Zhou, Wei Wang, Shengtao Zhou
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (12): 3476–3478.
https://doi.org/10.1158/1078-0432.CCR-19-0853
Published: 14 June 2019
View article titled, A Novel Autocrine CXCL14/ACKR2 Axis: The Achilles' Heel of Cancer Metastasis?
Open the PDF for A Novel Autocrine CXCL14/ACKR2 Axis: The Achilles' Heel of Cancer Metastasis? in another window
Journal Articles

Surufatinib in Advanced Well-Differentiated Neuroendocrine Tumors: A Multicenter, Single-Arm, Open-Label, Phase Ib/II Trial

Jianming Xu, Jie Li, Chunmei Bai, Nong Xu, Zhiwei Zhou, Zhiping Li, Caicun Zhou, Ru Jia, Ming Lu, Yuejuan Cheng, Chenyu Mao, Wei Wang, Ke Cheng, Chunxia Su, Ye Hua, Chuan Qi, Jing Li, Wei Wang, Ke Li, Qiaoling Sun, Yongxin Ren, Weiguo Su
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (12): 3486–3494.
https://doi.org/10.1158/1078-0432.CCR-18-2994
Published: 14 June 2019
View article titled, Surufatinib in Advanced Well-Differentiated Neuroendocrine Tumors: A Multicenter, Single-Arm, Open-Label, Phase Ib/II Trial
Open the PDF for Surufatinib in Advanced Well-Differentiated Neuroendocrine Tumors: A Multicenter, Single-Arm, Open-Label, Phase Ib/II Trial in another window
Includes: Supplementary data
Journal Articles

Abstract PR13: MET copy number gain is associated with gefitinib resistance in leptomeningeal carcinomatosis of EGFR-mutant lung cancer

Shigeki Nanjo, Sachiko Arai, Wei Wang, Akito Hata, Nobuyuki Katakami, Seiji Yano
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (17_Supplement): PR13.
https://doi.org/10.1158/1557-3265.AACRIASLC18-PR13
Published: 01 September 2018
View article titled, Abstract PR13: MET copy number gain is associated with gefitinib resistance in leptomeningeal carcinomatosis of EGFR-mutant lung cancer
Journal Articles

Neuroblastoma Patients' KIR and KIR-Ligand Genotypes Influence Clinical Outcome for Dinutuximab-based Immunotherapy: A Report from the Children's Oncology Group

Amy K. Erbe, Wei Wang, Lakeesha Carmichael, KyungMann Kim, Eneida A. Mendonça, Yiqiang Song, Dustin Hess, Patrick K. Reville, Wendy B. London, Arlene Naranjo, Jacquelyn A. Hank, Mitchell B. Diccianni, Ralph A. Reisfeld, Stephen D. Gillies, Katherine K. Matthay, Susan L. Cohn, Michael D. Hogarty, John M. Maris, Julie R. Park, M. Fevzi Ozkaynak, Andrew L. Gilman, Alice L. Yu, Paul M. Sondel
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (1): 189–196.
https://doi.org/10.1158/1078-0432.CCR-17-1767
Published: 02 January 2018
View article titled, Neuroblastoma Patients' KIR and KIR-Ligand Genotypes Influence Clinical Outcome for Dinutuximab-based Immunotherapy: A Report from the Children's Oncology Group
Open the PDF for Neuroblastoma Patients' KIR and KIR-Ligand Genotypes Influence Clinical Outcome for Dinutuximab-based Immunotherapy: A Report from the Children's Oncology Group in another window
Includes: Supplementary data
Journal Articles

FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma

Amy K. Erbe, Wei Wang, Jacob Goldberg, Mikayla Gallenberger, KyungMann Kim, Lakeesha Carmichael, Dustin Hess, Eneida A. Mendonca, Yiqiang Song, Jacquelyn A. Hank, Su-Chun Cheng, Sabina Signoretti, Michael Atkins, Alexander Carlson, James W. Mier, David J. Panka, David F. McDermott, Paul M. Sondel
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (9): 2159–2168.
https://doi.org/10.1158/1078-0432.CCR-16-1874
Published: 30 April 2017
View article titled, FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma
Open the PDF for FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Efficacy of Anti-RON Antibody Zt/g4–Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeutics for Targeted Colorectal Cancer Therapy

Liang Feng, Hang-Ping Yao, Wei Wang, Yong-Qing Zhou, Jianwei Zhou, Ruiwen Zhang, Ming-Hai Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (23): 6045–6058.
https://doi.org/10.1158/1078-0432.CCR-14-0898
Published: 30 November 2014
View article titled, Efficacy of Anti-RON Antibody Zt/g4–Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeutics for Targeted Colorectal Cancer Therapy
Open the PDF for Efficacy of Anti-RON Antibody Zt/g4–Drug Maytansinoid Conjugation (Anti-RON ADC) as a Novel Therapeutics for Targeted Colorectal Cancer Therapy in another window
Includes: Supplementary data
Journal Articles

CHM-1, a novel synthetic quinolone with potent and selective antitumor activity against human hepatocellular carcinoma

Shih-Wei Wang, Shiow-Lin Pan, Jih-Hwa Guh, Sheng-Chu Kuo, Kuo-Hsiung Lee, Che-Ming Teng
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): A37.
Published: 15 August 2014
View article titled, CHM-1, a novel synthetic quinolone with potent and selective antitumor activity against human hepatocellular carcinoma
Journal Articles

Moscatilin, a novel tumor vascular-targeting agent, induced cell cycle arrest and apoptosis in human umbilical vein endothelial cells

An-Chi Tsai, Shiow-Lin Pan, Shih-Wei Wang, Jih-Hwa Guh, Hui-Lung Sun, Yi-Nan Liu, Cho-Hwa Liao, Chien-Chih Chen, Che-Ming Teng
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22_Supplement): B44.
Published: 15 August 2014
View article titled, Moscatilin, a novel tumor vascular-targeting agent, induced cell cycle arrest and apoptosis in human umbilical vein endothelial cells
Journal Articles

IL-17A Stimulates the Progression of Giant Cell Tumors of Bone

Meng Xu, Zhi-Gang Song, Cheng-Xiong Xu, Guang-Hua Rong, Ke-Xing Fan, Ji-Ying Chen, Wei Zhang, Jin-Peng Jia, Gang Han, Wei Wang, Wei Chai, Wen-Tao Liang, Wen-Zhi Bi, Yan Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (17): 4697–4705.
https://doi.org/10.1158/1078-0432.CCR-13-0251
Published: 02 September 2013
View article titled, IL-17A Stimulates the Progression of Giant Cell Tumors of Bone
Open the PDF for IL-17A Stimulates the Progression of Giant Cell Tumors of Bone in another window
Includes: Supplementary data
Journal Articles

Evaluation of Midkine as a Diagnostic Serum Biomarker in Hepatocellular Carcinoma

Wen-Wei Zhu, Jia-Jian Guo, Lei Guo, Hu-Liang Jia, Ming Zhu, Ju-Bo Zhang, Christopher A. Loffredo, Marshonna Forgues, Hua Huang, Xu-Jian Xing, Ning Ren, Qiong-Zhu Dong, Hai-Jun Zhou, Zheng-Gang Ren, Nai-Qing Zhao, Xin Wei Wang, Zhao-You Tang, Lun-Xiu Qin, Qing-Hai Ye
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (14): 3944–3954.
https://doi.org/10.1158/1078-0432.CCR-12-3363
Published: 15 July 2013
View article titled, Evaluation of Midkine as a Diagnostic Serum Biomarker in Hepatocellular Carcinoma
Open the PDF for Evaluation of Midkine as a Diagnostic Serum Biomarker in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Sorafenib or Placebo with Either Gemcitabine or Capecitabine in Patients with HER-2–Negative Advanced Breast Cancer That Progressed during or after Bevacizumab

Lee S. Schwartzberg, Kurt W. Tauer, Robert C. Hermann, Grace Makari-Judson, Claudine Isaacs, J. Thaddeus Beck, Virginia Kaklamani, Edward J. Stepanski, Hope S. Rugo, Wei Wang, Katherine Bell-McGuinn, Jeffrey J. Kirshner, Peter Eisenberg, Richard Emanuelson, Mark Keaton, Ellis Levine, Diana C. Medgyesy, Rubina Qamar, Alexander Starr, Sunhee Kwon Ro, Nathalie A. Lokker, Clifford A. Hudis
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (10): 2745–2754.
https://doi.org/10.1158/1078-0432.CCR-12-3177
Published: 12 May 2013
View article titled, Sorafenib or Placebo with Either Gemcitabine or Capecitabine in Patients with HER-2–Negative Advanced Breast Cancer That Progressed during or after Bevacizumab
Open the PDF for Sorafenib or Placebo with Either Gemcitabine or Capecitabine in Patients with HER-2–Negative Advanced Breast Cancer That Progressed during or after Bevacizumab in another window
Includes: Supplementary data
Journal Articles

An International Collaboration to Harmonize the Quantitative Plasma Epstein-Barr Virus DNA Assay for Future Biomarker-Guided Trials in Nasopharyngeal Carcinoma

Quynh-Thu Le, Qiang Zhang, Hongbin Cao, Ann-Joy Cheng, Benjamin A. Pinsky, Ruey-Long Hong, Joseph T. Chang, Chun-Wei Wang, Kuo-Chien Tsao, YM Dennis Lo, Nancy Lee, K. Kian Ang, Anthony T.C. Chan, K.C. Allen Chan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (8): 2208–2215.
https://doi.org/10.1158/1078-0432.CCR-12-3702
Published: 15 April 2013
View article titled, An International Collaboration to Harmonize the Quantitative Plasma Epstein-Barr Virus DNA Assay for Future Biomarker-Guided Trials in Nasopharyngeal Carcinoma
Open the PDF for An International Collaboration to Harmonize the Quantitative Plasma Epstein-Barr Virus DNA Assay for Future Biomarker-Guided Trials in Nasopharyngeal Carcinoma in another window
Includes: Supplementary data
Journal Articles

Arylsulfonamide KCN1 Inhibits In Vivo Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1α Interaction with Cofactors p300/CBP

Shaoman Yin, Stefan Kaluz, Narra S. Devi, Adnan A. Jabbar, Rita G. de Noronha, Jiyoung Mun, Zhaobin Zhang, Purushotham R. Boreddy, Wei Wang, Zhibo Wang, Thomas Abbruscato, Zhengjia Chen, Jeffrey J. Olson, Ruiwen Zhang, Mark M. Goodman, K.C. Nicolaou, Erwin G. Van Meir
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (24): 6623–6633.
https://doi.org/10.1158/1078-0432.CCR-12-0861
Published: 16 December 2012
View article titled, Arylsulfonamide KCN1 Inhibits <em>In Vivo</em> Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1α Interaction with Cofactors p300/CBP
Open the PDF for Arylsulfonamide KCN1 Inhibits <em>In Vivo</em> Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1α Interaction with Cofactors p300/CBP in another window
Includes: Supplementary data
Journal Articles

HDAC Inhibitors Augmented Cell Migration and Metastasis through Induction of PKCs Leading to Identification of Low Toxicity Modalities for Combination Cancer Therapy

Kuen-Tyng Lin, Yi-Wei Wang, Chiung-Tong Chen, Chun-Ming Ho, Wen-Hui Su, Yuh-Shan Jou
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4691–4701.
https://doi.org/10.1158/1078-0432.CCR-12-0633
Published: 30 August 2012
View article titled, HDAC Inhibitors Augmented Cell Migration and Metastasis through Induction of PKCs Leading to Identification of Low Toxicity Modalities for Combination Cancer Therapy
Open the PDF for HDAC Inhibitors Augmented Cell Migration and Metastasis through Induction of PKCs Leading to Identification of Low Toxicity Modalities for Combination Cancer Therapy in another window
Includes: Supplementary data