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Wei Huang
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Journal Articles

Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer

Yu Rebecca Miao, Kaushik N. Thakkar, Jin Qian, Mihalis S. Kariolis, Wei Huang, Saravanan Nandagopal, Teddy Tat Chi Yang, Anh N. Diep, Gerald Maxwell Cherf, Yu Xu, Eui Jung Moon, Yiren Xiao, Haizea Alemany, Tiane Li, Wenhua Yu, Bo Wei, Erinn B. Rankin, Amato J. Giaccia
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (15): 4435–4448.
https://doi.org/10.1158/1078-0432.CCR-20-0482
Published: 01 August 2021
View article titled, Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract B45: High-throughput label-free isolation and expansion of circulating tumor cells (CTCs) from non-small cell lung cancer (NSCLC) patients for personalized treatments

Mina Zeinali, Wei Huang, Maggie Lee, Arthi Nadhan, Anvya Mathur, Casey Hedman, Eric Lin, Ramdane Harouaka, Max S. Wicha, Lili Zhao, Nallasivam Palanisamy, Mathias Hafner, Rishindra Reddy, Gregory P. Kalemkerian, Bryan J. Schneider, Khaled A. Hassan, Nithya Ramnath, Sunitha Nagrath
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (11_Supplement): B45.
https://doi.org/10.1158/1557-3265.LiqBiop20-B45
Published: 01 June 2020
View article titled, Abstract B45: High-throughput label-free isolation and expansion of circulating tumor cells (CTCs) from non-small cell lung cancer (NSCLC) patients for personalized treatments
Journal Articles

NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma

Xin Xu, Wei Huang, Andras Heczey, Daofeng Liu, Linjie Guo, Michael Wood, Jingling Jin, Amy N. Courtney, Bin Liu, Erica J. Di Pierro, John Hicks, Gabriel A. Barragan, Ho Ngai, Yuhui Chen, Barbara Savoldo, Gianpietro Dotti, Leonid S. Metelitsa
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (23): 7126–7138.
https://doi.org/10.1158/1078-0432.CCR-19-0421
Published: 02 December 2019
View article titled, NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced <em>In Vivo</em> Persistence and Antitumor Activity against Neuroblastoma
Open the PDF for NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced <em>In Vivo</em> Persistence and Antitumor Activity against Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer

Yi Xiao, Ding Ma, Shen Zhao, Chen Suo, Jinxiu Shi, Meng-Zhu Xue, Miao Ruan, Hai Wang, Jingjing Zhao, Qin Li, Peng Wang, Leming Shi, Wen-Tao Yang, Wei Huang, Xin Hu, Ke-Da Yu, Shenglin Huang, François Bertucci, Yi-Zhou Jiang, Zhi-Ming Shao
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (16): 5002–5014.
https://doi.org/10.1158/1078-0432.CCR-18-3524
Published: 15 August 2019
View article titled, Multi-Omics Profiling Reveals Distinct Microenvironment Characterization and Suggests Immune Escape Mechanisms of Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia

Wen-Tao Wang, Cai Han, Yu-Meng Sun, Zhen-Hua Chen, Ke Fang, Wei Huang, Lin-Yu Sun, Zhan-Cheng Zeng, Xue-Qun Luo, Yue-Qin Chen
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (9): 2795–2808.
https://doi.org/10.1158/1078-0432.CCR-18-1474
Published: 01 May 2019
View article titled, Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia
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Includes: Supplementary data
Journal Articles

Abstract A21: High-throughput isolation of circulating tumor cells (CTCs) from non-small cell lung cancer (NSCLC) patients for personalized treatments

Mina Zeinali, Arthi Nadhan, Anvya Mathur, Maggie Lee, Wei Huang, Mathias Hafner, Nithya Ramnath, Sunitha Nagrath
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (17_Supplement): A21.
https://doi.org/10.1158/1557-3265.AACRIASLC18-A21
Published: 01 September 2018
View article titled, Abstract A21: High-throughput isolation of circulating tumor cells (CTCs) from non-small cell lung cancer (NSCLC) patients for personalized treatments
Journal Articles

Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics

Joyce F. Liu, Sangeetha Palakurthi, Qing Zeng, Shan Zhou, Elena Ivanova, Wei Huang, Ioannis K. Zervantonakis, Laura M. Selfors, Yiping Shen, Colin C. Pritchard, Mei Zheng, Vilmos Adleff, Eniko Papp, Huiying Piao, Marian Novak, Susan Fotheringham, Gerburg M. Wulf, Jessie English, Paul T. Kirschmeier, Victor E. Velculescu, Cloud Paweletz, Gordon B. Mills, David M. Livingston, Joan S. Brugge, Ursula A. Matulonis, Ronny Drapkin
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (5): 1263–1273.
https://doi.org/10.1158/1078-0432.CCR-16-1237
Published: 28 February 2017
View article titled, Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics
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Includes: Supplementary data
Journal Articles

Quantitative Imaging in Cancer Clinical Trials

Thomas E. Yankeelov, David A. Mankoff, Lawrence H. Schwartz, Frank S. Lieberman, John M. Buatti, James M. Mountz, Bradley J. Erickson, Fiona M.M. Fennessy, Wei Huang, Jayashree Kalpathy-Cramer, Richard L. Wahl, Hannah M. Linden, Paul E. Kinahan, Binsheng Zhao, Nola M. Hylton, Robert J. Gillies, Laurence Clarke, Robert Nordstrom, Daniel L. Rubin
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (2): 284–290.
https://doi.org/10.1158/1078-0432.CCR-14-3336
Published: 14 January 2016
View article titled, Quantitative Imaging in Cancer Clinical Trials
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Journal Articles

Phase I Trial of Preoperative Chemoradiation plus Sorafenib for High-Risk Extremity Soft Tissue Sarcomas with Dynamic Contrast-Enhanced MRI Correlates

Janelle M. Meyer, Kelly S. Perlewitz, James B. Hayden, Yee-Cheen Doung, Arthur Y. Hung, John T. Vetto, Rodney F. Pommier, Atiya Mansoor, Brooke R. Beckett, Alina Tudorica, Motomi Mori, Megan L. Holtorf, Aneela Afzal, William J. Woodward, Eve T. Rodler, Robin L. Jones, Wei Huang, Christopher W. Ryan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (24): 6902–6911.
https://doi.org/10.1158/1078-0432.CCR-13-1594
Published: 16 December 2013
View article titled, Phase I Trial of Preoperative Chemoradiation plus Sorafenib for High-Risk Extremity Soft Tissue Sarcomas with Dynamic Contrast-Enhanced MRI Correlates
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Journal Articles

Homozygous Deletion of MTAP Gene as a Poor Prognosticator in Gastrointestinal Stromal Tumors

Hsuan-Ying Huang, Shau-Hsuan Li, Shih-Chen Yu, Fong-Fu Chou, Ching-Cherng Tzeng, Tsung-Hui Hu, Yih-Huei Uen, Yu-Fang Tian, Yu-Hui Wang, Fu-Min Fang, Wen-Wei Huang, Yu-Ching Wei, Jing-Mei Wu, Chien-Feng Li
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 6963–6972.
https://doi.org/10.1158/1078-0432.CCR-09-1511
Published: 11 November 2009
View article titled, Homozygous Deletion of <em>MTAP</em> Gene as a Poor Prognosticator in Gastrointestinal Stromal Tumors
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Includes: Supplementary data
Journal Articles

Heat Shock Protein 90 Overexpression Independently Predicts Inferior Disease-Free Survival with Differential Expression of the α and β Isoforms in Gastrointestinal Stromal Tumors

Chien-Feng Li, Wen-Wei Huang, Jing-Mei Wu, Shih-Chen Yu, Tsung-Hui Hu, Yih-Huei Uen, Yu-Fang Tian, Ching-Nan Lin, David Lu, Fu-Min Fang, Hsuan-Ying Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7822–7831.
https://doi.org/10.1158/1078-0432.CCR-08-1369
Published: 01 December 2008
View article titled, Heat Shock Protein 90 Overexpression Independently Predicts Inferior Disease-Free Survival with Differential Expression of the α and β Isoforms in Gastrointestinal Stromal Tumors
Open the PDF for Heat Shock Protein 90 Overexpression Independently Predicts Inferior Disease-Free Survival with Differential Expression of the α and β Isoforms in Gastrointestinal Stromal Tumors in another window
Includes: Supplementary data
Journal Articles

Immunohistochemical and Biogenetic Features of Diffuse-Type Tenosynovial Giant Cell Tumors: The Potential Roles of Cyclin A, P53, and Deletion of 15q in Sarcomatous Transformation

Hsuan-Ying Huang, Robert B. West, Ching-Cherng Tzeng, Matt van de Rijn, Jun-Wen Wang, Shih-Cheng Chou, Wen-Wei Huang, Hock-Liew Eng, Ching-Nan Lin, Shih-Chen Yu, Jing-Mei Wu, Chiu-Chin Lu, Chien-Feng Li
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19): 6023–6032.
https://doi.org/10.1158/1078-0432.CCR-08-0252
Published: 30 September 2008
View article titled, Immunohistochemical and Biogenetic Features of Diffuse-Type Tenosynovial Giant Cell Tumors: The Potential Roles of Cyclin A, P53, and Deletion of 15q in Sarcomatous Transformation
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Journal Articles

Tagging Single Nucleotide Polymorphisms in Phosphoinositide-3-Kinase–Related Protein Kinase Genes Involved in DNA Damage “Checkpoints” and Lung Cancer Susceptibility

Zhibin Hu, Hongliang Liu, Haifeng Wang, Ruifen Miao, Weiwei Sun, Guangfu Jin, Ying Wang, Hongxia Ma, Li Jin, Qingyi Wei, Daru Lu, Wei Huang, Hongbing Shen
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2887–2891.
https://doi.org/10.1158/1078-0432.CCR-07-1822
Published: 01 May 2008
View article titled, Tagging Single Nucleotide Polymorphisms in Phosphoinositide-3-Kinase–Related Protein Kinase Genes Involved in DNA Damage “Checkpoints” and Lung Cancer Susceptibility
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Journal Articles

Hypomethylated P4 Promoter Induces Expression of the Insulin-Like Growth Factor-II Gene in Hepatocellular Carcinoma in a Chinese Population

Shao Hui Tang, Dong Hua Yang, Wei Huang, Hong Ke Zhou, Xiao Hua Lu, Gang Ye
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (14): 4171–4177.
https://doi.org/10.1158/1078-0432.CCR-05-2261
Published: 20 July 2006
View article titled, Hypomethylated P4 Promoter Induces Expression of the <em>Insulin-Like Growth Factor-II</em> Gene in Hepatocellular Carcinoma in a Chinese Population
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