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Waun Ki Hong
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Journal Articles

VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy

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Erick Riquelme, Milind Suraokar, Carmen Behrens, Heather Y. Lin, Luc Girard, Monique B. Nilsson, George Simon, Jing Wang, Kevin R. Coombes, J. Jack Lee, Waun Ki Hong, John Heymach, John D. Minna, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (14): 3849–3861.
https://doi.org/10.1158/1078-0432.CCR-13-1916
Published: 14 July 2014
View articletitled, VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy
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Includes: Supplementary data
Journal Articles

Predictors of Survival in Never-Smokers with Non–Small Cell Lung Cancer: A Large-Scale, Two-Phase Genetic Study

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Xia Pu, Yuanqing Ye, Margaret R. Spitz, Liang Wang, Jian Gu, Scott M. Lippman, Michelle A.T. Hildebrandt, Waun Ki Hong, John D. Minna, Jack A. Roth, Ping Yang, Xifeng Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (21): 5983–5991.
https://doi.org/10.1158/1078-0432.CCR-12-0774
Published: 06 November 2012
View articletitled, Predictors of Survival in Never-Smokers with Non–Small Cell Lung Cancer: A Large-Scale, Two-Phase Genetic Study
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Includes: Supplementary data
Journal Articles

Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor/Recurrence Risk and Response to Retinoid Chemoprevention

Free
Michelle A.T. Hildebrandt, Scott M. Lippman, Carol J. Etzel, Edward Kim, J. Jack Lee, Fadlo R. Khuri, Margaret R. Spitz, Reuben Lotan, Waun Ki Hong, Xifeng Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (13): 3705–3713.
https://doi.org/10.1158/1078-0432.CCR-11-3271
Published: 01 July 2012
View articletitled, Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor/Recurrence Risk and Response to Retinoid Chemoprevention
Open the PDF for Genetic Variants in the PI3K/PTEN/AKT/mTOR Pathway Predict Head and Neck Cancer Patient Second Primary Tumor/Recurrence Risk and Response to Retinoid Chemoprevention in another window
Includes: Supplementary data
Journal Articles

Abstract IA20: Targeted lung cancer chemoprevention through reverse migration

Free
Waun Ki Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): IA20.
https://doi.org/10.1158/1078-0432.12AACRIASLC-IA20
Published: 01 February 2012
View articletitled, Abstract IA20: Targeted lung cancer chemoprevention through reverse migration
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Journal Articles

Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis

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Ximing Tang, Humam Kadara, Carmen Behrens, Diane D Liu, Yun Xiao, David Rice, Adi F. Gazdar, Junya Fujimoto, Cesar Moran, Marileila Varella-Garcia, J Jack Lee, Waun Ki Hong, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (8): 2434–2443.
https://doi.org/10.1158/1078-0432.CCR-10-1412
Published: 14 April 2011
View articletitled, Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis
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Includes: Supplementary data
Journal Articles

Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer

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Jae Yong Cho, Jae Yun Lim, Jae Ho Cheong, Yun-Yong Park, Se-Lyun Yoon, Soo Mi Kim, Sang-Bae Kim, Hoguen Kim, Soon Won Hong, Young Nyun Park, Sung Hoon Noh, Eun Sung Park, In-Sun Chu, Waun Ki Hong, Jaffer A. Ajani, Ju-Seog Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1850–1857.
https://doi.org/10.1158/1078-0432.CCR-10-2180
Published: 31 March 2011
View articletitled, Gene Expression Signature–Based Prognostic Risk Score in Gastric Cancer
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Includes: Supplementary data
Journal Articles

A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma Prognosis

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Humam Kadara, Carmen Behrens, Ping Yuan, Luisa Solis, Diane Liu, Xuemin Gu, John D. Minna, J. Jack Lee, Edward Kim, Waun-Ki Hong, Ignacio I. Wistuba, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (6): 1490–1501.
https://doi.org/10.1158/1078-0432.CCR-10-2703
Published: 15 March 2011
View articletitled, A Five-Gene and Corresponding Protein Signature for Stage-I Lung Adenocarcinoma Prognosis
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Includes: Supplementary data
Journal Articles

Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

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Li-E Wang, Zhibin Hu, Erich M. Sturgis, Margaret R. Spitz, Sara S. Strom, Christopher I. Amos, Zhaozheng Guo, Yawei Qiao, Ann Marie Gillenwater, Jeffrey N. Myers, Gary L. Clayman, Randal S. Weber, Adel K. El-Naggar, Li Mao, Scott M. Lippman, Waun Ki Hong, Qingyi Wei
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 764–774.
https://doi.org/10.1158/1078-0432.CCR-09-2156
Published: 14 January 2010
View articletitled, Reduced DNA Repair Capacity for Removing Tobacco Carcinogen–Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics
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Journal Articles

Expression of Interleukin-1 Receptor–Associated Kinase-1 in Non–Small Cell Lung Carcinoma and Preneoplastic Lesions

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Carmen Behrens, Lei Feng, Humam Kadara, Hyun-Jung Kim, J. Jack Lee, Reza Mehran, Waun Ki Hong, Reuben Lotan, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (1): 34–44.
https://doi.org/10.1158/1078-0432.CCR-09-0650
Published: 04 January 2010
View articletitled, Expression of Interleukin-1 Receptor–Associated Kinase-1 in Non–Small Cell Lung Carcinoma and Preneoplastic Lesions
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Includes: Supplementary data
Journal Articles

ΔNp63 Overexpression, Alone and in Combination with Other Biomarkers, Predicts the Development of Oral Cancer in Patients with Leukoplakia

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Pierre Saintigny, Adel K. El-Naggar, Vali Papadimitrakopoulou, Hening Ren, You-Hong Fan, Lei Feng, J. Jack Lee, Edward S. Kim, Waun Ki Hong, Scott M. Lippman, Li Mao
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (19): 6284–6291.
https://doi.org/10.1158/1078-0432.CCR-09-0498
Published: 30 September 2009
View articletitled, ΔNp63 Overexpression, Alone and in Combination with Other Biomarkers, Predicts the Development of Oral Cancer in Patients with Leukoplakia
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Journal Articles

HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors

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Menghong Sun, Carmen Behrens, Lei Feng, Natalie Ozburn, Ximing Tang, Guosheng Yin, Ritsuko Komaki, Marileila Varella-Garcia, Waun Ki Hong, Kenneth D. Aldape, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (15): 4829–4837.
https://doi.org/10.1158/1078-0432.CCR-08-2921
Published: 29 July 2009
View articletitled, HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors
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Includes: Supplementary data
Journal Articles

Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer

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Carmen Behrens, Heather Y. Lin, J. Jack Lee, Maria Gabriela Raso, Waun Ki Hong, Ignacio I. Wistuba, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19): 6014–6022.
https://doi.org/10.1158/1078-0432.CCR-08-0167
Published: 30 September 2008
View articletitled, Immunohistochemical Expression of Basic Fibroblast Growth Factor and Fibroblast Growth Factor Receptors 1 and 2 in the Pathogenesis of Lung Cancer
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Journal Articles

Implication of the Insulin-like Growth Factor-IR Pathway in the Resistance of Non–small Cell Lung Cancer Cells to Treatment with Gefitinib

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Floriana Morgillo, Woo-Young Kim, Edward S. Kim, Fortunato Ciardiello, Waun Ki Hong, Ho-Young Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (9): 2795–2803.
https://doi.org/10.1158/1078-0432.CCR-06-2077
Published: 01 May 2007
View articletitled, Implication of the Insulin-like Growth Factor-IR Pathway in the Resistance of Non–small Cell Lung Cancer Cells to Treatment with Gefitinib
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Journal Articles

Joint Effect of Mutagen Sensitivity and Insulin-Like Growth Factors in Predicting the Risk of Developing Secondary Primary Tumors and Tumor Recurrence in Patients with Head and Neck Cancer

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Xifeng Wu, Jian Gu, Qiong Dong, Maosheng Huang, Kim-Anh Do, Waun Ki Hong, Margaret R. Spitz
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (23): 7194–7201.
https://doi.org/10.1158/1078-0432.CCR-06-0671
Published: 04 December 2006
View articletitled, Joint Effect of Mutagen Sensitivity and Insulin-Like Growth Factors in Predicting the Risk of Developing Secondary Primary Tumors and Tumor Recurrence in Patients with Head and Neck Cancer
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Journal Articles

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

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Gary J. Kelloff, Scott M. Lippman, Andrew J. Dannenberg, Caroline C. Sigman, Homer L. Pearce, Brian J. Reid, Eva Szabo, V. Craig Jordan, Margaret R. Spitz, Gordon B. Mills, Vali A. Papadimitrakopoulou, Reuben Lotan, Bharat B. Aggarwal, Robert S. Bresalier, Jeri Kim, Banu Arun, Karen H. Lu, Melanie E. Thomas, Helen E. Rhodes, Molly A. Brewer, Michele Follen, Dong M. Shin, Howard L. Parnes, Jill M. Siegfried, Alison A. Evans, William J. Blot, Wong-Ho Chow, Patricia L. Blount, Carlo C. Maley, Kenneth K. Wang, Stephen Lam, J. Jack Lee, Steven M. Dubinett, Paul F. Engstrom, Frank L. Meyskens, Jr., Joyce O'Shaughnessy, Ernest T. Hawk, Bernard Levin, William G. Nelson, Waun Ki Hong, for the AACR Task Force on Cancer Prevention
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (12): 3661–3697.
https://doi.org/10.1158/1078-0432.CCR-06-1104
Published: 15 June 2006
View articletitled, Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward
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Journal Articles

Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia

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Scott M. Lippman, J. Jack Lee, Jack W. Martin, Adel K. El-Naggar, Xiaochun Xu, Dong M. Shin, Margaret Thomas, Li Mao, Herbert A. Fritsche, Jr., Xian Zhou, Vassiliki Papadimitrakopoulou, Fadlo R. Khuri, Hai Tran, Gary L. Clayman, Walter N. Hittelman, Waun Ki Hong, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (10): 3109–3114.
https://doi.org/10.1158/1078-0432.CCR-05-2636
Published: 17 May 2006
View articletitled, Fenretinide Activity in Retinoid-Resistant Oral Leukoplakia
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Journal Articles

Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer

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Ho-Young Lee, Seung-Hyun Oh, Young-Ah Suh, Jin Hyen Baek, Vali Papadimitrakopoulou, Suyun Huang, Waun Ki Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (16): 6065–6074.
https://doi.org/10.1158/1078-0432.CCR-05-0009
Published: 22 August 2005
View articletitled, Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer
Open the PDF for Response of Non–Small Cell Lung Cancer Cells to the Inhibitors of Phosphatidylinositol 3-Kinase/Akt- and MAPK Kinase 4/c-Jun NH2-Terminal Kinase Pathways: An Effective Therapeutic Strategy for Lung Cancer in another window
Journal Articles

Thymidylate Synthase 5′- and 3′-Untranslated Region Polymorphisms Associated with Risk and Progression of Squamous Cell Carcinoma of the Head and Neck

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Zhengdong Zhang, Qiuling Shi, Erich M. Sturgis, Margaret R. Spitz, Waun Ki Hong, Qingyi Wei
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (23): 7903–7910.
https://doi.org/10.1158/1078-0432.CCR-04-0923
Published: 07 December 2004
View articletitled, Thymidylate Synthase 5′- and 3′-Untranslated Region Polymorphisms Associated with Risk and Progression of Squamous Cell Carcinoma of the Head and Neck
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Journal Articles

Value of p16 INK4a and RASSF1A Promoter Hypermethylation in Prognosis of Patients with Resectable Non–Small Cell Lung Cancer

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Jie Wang, J. Jack Lee, Luo Wang, Diane D. Liu, Charles Lu, You-Hong Fan, Waun Ki Hong, Li Mao
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (18): 6119–6125.
https://doi.org/10.1158/1078-0432.CCR-04-0652
Published: 24 September 2004
View articletitled, Value of p16 INK4a and RASSF1A Promoter Hypermethylation in Prognosis of Patients with Resectable Non–Small Cell Lung Cancer
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Journal Articles

Serum Levels of Insulin Growth Factor (IGF-I) and IGF-Binding Protein Predict Risk of Second Primary Tumors in Patients with Head and Neck Cancer

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Xifeng Wu, Hua Zhao, Kim-Anh Do, Marcella M. Johnson, Qiong Dong, Waun Ki Hong, Margaret R. Spitz
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (12): 3988–3995.
https://doi.org/10.1158/1078-0432.CCR-03-0762
Published: 24 June 2004
View articletitled, Serum Levels of Insulin Growth Factor (IGF-I) and IGF-Binding Protein Predict Risk of Second Primary Tumors in Patients with Head and Neck Cancer
Open the PDF for Serum Levels of Insulin Growth Factor (IGF-I) and IGF-Binding Protein Predict Risk of Second Primary Tumors in Patients with Head and Neck Cancer in another window